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764 suspected (536 clinical and 220 non-clinical) cases / 6 confirmed cases ; 187 (+2) suspected ZIKV positive pregnancies, 19 (+1) suspected neurological cases (including 1 case of GBS ) and 359 (+10) ZIKV associated cases of microcephaly/ CNS (cognitive)...Today, 11:36 AM
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Chin Med J (Engl). 2018 Nov 20;131(22):2765-2766. doi: 10.4103/0366-6999.245268.
Severe Lymphopenia and Related T-cell Immunity in an Avian Influenza A (H7N9)-Infected Patient.
Zhang NN1, Zhang Y2, Xia JG2, Li M2, Huang X2, Zhang RY2, Zhan QY1.
Author informati
...Today, 04:06 AM -
Indian J Med Res. 2018 Sep;148(3):329-333. doi: 10.4103/ijmr.IJMR_890_17.
Respiratory viruses in returning Hajj & Umrah pilgrims with acute respiratory illness in 2014-2015.
Koul PA1, Mir H1, Saha S2, Chadha MS3, Potdar V3, Widdowson MA2, Lal RB2, Krishnan A4.
Author information
Abstract
...Today, 04:05 AM -
Emerg Microbes Infect. 2018 Nov 14;7(1):179. doi: 10.1038/s41426-018-0182-2.
Broad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017.
Chen C1, Liu Z1, Liu L1, Xiao Y1, Wang J2, Jin Q3,4.
Author information
Abstr
...Today, 04:04 AM -
G Ital Cardiol (Rome). 2018 Nov;19(11):620-627. doi: 10.1714/3012.30109.
[Influenza infection and risk of myocardial infarction: the protective effect of influenza vaccination. One more reason to vaccinate].
[Article in Italian]
Coutsoumbas GV1, Di Pasquale G1.
Author in
...Today, 04:03 AM -
Int J Nanomedicine. 2018 Oct 24;13:6699-6715. doi: 10.2147/IJN.S178809. eCollection 2018.
Liposomal nanoparticle-based conserved peptide influenza vaccine and monosodium urate crystal adjuvant elicit protective immune response in pigs.
Dhakal S1,2, Cheng X3, Salcido J3, Renu S1,2, Bondra K1,2, Lakshmanappa YS1,2, Misch C1,2, Ghimire S1,2, Feliciano-Ruiz N1,2, Hogshead B1,2, Krakowka S4, Carson K3, McDonough J3, Lee CW1,2, Renukaradhya GJ1,2.
Author information
Abstract
Background:
Influenza (flu) is a constant threat to humans and animals, and vaccination is one of the most effective ways to mitigate the disease. Due to incomplete protection induced by current flu vaccines, development of novel flu vaccine candidates is warranted to achieve greater efficacy against constantly evolving flu viruses.
Methods:
In the present study, we used liposome nanoparticle (<200 nm diameter)-based subunit flu vaccine containing ten encapsulated highly conserved B and T cell epitope peptides to induce protective immune response against a zoonotic swine influenza A virus (SwIAV) H1N1 challenge infection in a pig model. Furthermore, we used monosodium urate (MSU) crystals as an adjuvant and co-administered the vaccine formulation as an intranasal mist to flu-free nursery pigs, twice at 3-week intervals.
Results:
Liposome peptides flu vaccine delivered with MSU adjuvant improved the hemagglutination inhibition antibody titer and mucosal IgA response against the SwIAV challenge and also against two other highly genetically variant IAVs. Liposomal vaccines also enhanced the frequency of peptides and virus-specific T-helper/memory cells and IFN-γ response. The improved specific cellular and mucosal humoral immune responses in adjuvanted liposomal peptides flu vaccine partially protected pigs from flu-induced fever and pneumonic lesions, and reduced the nasal virus shedding and viral load in the lungs.
Conclusion:
Overall, our study shows great promise for using liposome...Today, 04:02 AM -
Front Microbiol. 2018 Oct 30;9:2570. doi: 10.3389/fmicb.2018.02570. eCollection 2018.
Topical Application of a Vitamin A Derivative and Its Combination With Non-ablative Fractional Laser Potentiates Cutaneous Influenza Vaccination.
Li P1,2,3, Wang J2,4, Cao M1, Deng Q3, Jiang S1,5, Wu MX2,6, Lu L1. ...Today, 04:01 AM -
Case Rep Crit Care. 2018 Oct 22;2018:6973197. doi: 10.1155/2018/6973197. eCollection 2018.
Veno-Arterial Extracorporeal Membrane Oxygenation for Septic Cardiomyopathy due to Legionella Pneumonia after Influenza Virus Infection.
Asaki M1, Masuda T1, Miki Y1.
Author information
...Today, 04:00 AM -
Front Vet Sci. 2018 Oct 30;5:263. doi: 10.3389/fvets.2018.00263. eCollection 2018.
Detecting and Predicting Emerging Disease in Poultry With the Implementation of New Technologies and Big Data: A Focus on Avian Influenza Virus.
Astill J1, Fraser E2, Dara R3, Sharif S1.
Author information
...Today, 03:57 AM -
J Infect Dis. 2018 Nov 14. doi: 10.1093/infdis/jiy547. [Epub ahead of print]
Phase 2b Study of Pimodivir (JNJ-63623872) as Monotherapy or in Combination With Oseltamivir for Treatment of Acute Uncomplicated Seasonal Influenza A: TOPAZ Trial.
Finberg RW1, Lanno R2, Anderson D3, Fleischhackl R4, van Duijnhoven...Today, 03:56 AM -
Influenza Other Respir Viruses. 2018 Nov 14. doi: 10.1111/irv.12620. [Epub ahead of print]
Influenza epidemics observed in primary care from 1984 to 2017 in France: a decrease of epidemic size over time.
Souty C1, Amoros P1, Falchi A2, Capai L1,2, Bonmarin I3, van der Werf S4,5,6,7, Masse S1,2, Turbelin C1, Rossignol L1, Vilcu...Today, 03:55 AM -
J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Sep 21;1104:40-48. doi: 10.1016/j.jchromb.2018.09.020. [Epub ahead of print]
Application of stable isotope dimethyl labeling for MRM based absolute antigen quantification of influenza vaccine.
Huang SY1, Lin MH2, Chen YH2, Lai CC2, Lee MS2, Hu...Today, 03:54 AM -
Cardiology. 2018 Nov 14;141(2):98-106. doi: 10.1159/000493572. [Epub ahead of print]
Beneficial Effects of Vaccination on Cardiovascular Events: Myocardial Infarction, Stroke, Heart Failure.
Fountoulaki K1, Tsiodras S2, Polyzogopoulou E3, Olympios C4, Parissis J5.
Author information
...Today, 03:54 AM -
Viruses. 2018 Nov 13;10(11). pii: E627. doi: 10.3390/v10110627.
Causes and Consequences of Spatial Within-Host Viral Spread.
Gallagher ME1, Brooke CB2,3, Ke R4, Koelle K5.
Author information
Abstract
The spread of viral pathogens both between and within hosts is inherently...Today, 03:53 AM -
BMC Health Serv Res. 2018 Nov 14;18(1):853. doi: 10.1186/s12913-018-3659-8.
Motivators and barriers to vaccination of health professionals against seasonal influenza in primary healthcare.
Petek D1, Kamnik-Jug K2.
Author information
Abstract
BACKGROUND:
Over the last decade, the vaccination...Today, 03:51 AM -
Virol J. 2018 Nov 14;15(1):175. doi: 10.1186/s12985-018-1085-5.
Analysis of influenza B virus lineages and the HA1 domain of its hemagglutinin gene in Guangzhou, southern China, during 2016.
Ye F1, Chen XJ2, Guan WD2, Pan SH2, Yang ZF2, Chen RC2.
Author information
Abstract
BACKGR
...Today, 03:51 AM -
mSphere. 2018 Nov 14;3(6). pii: e00549-18. doi: 10.1128/mSphereDirect.00549-18.
Nucleolar Relocalization of RBM14 by Influenza A Virus NS1 Protein.
Beyleveld G1,2, Chin DJ3, Moreno Del Olmo E1, Carter J3, Najera I3,4, Cillóniz C3, Shaw ML5.
Author information
Abstr
...Today, 03:50 AM -
J Virol. 2018 Nov 14. pii: JVI.00946-18. doi: 10.1128/JVI.00946-18. [Epub ahead of print]
Elicitation of protective antibodies against 20 years of future H3N2 co-ciruculating influenza virus variants in ferrets preimmune to historical H3N2 influenza viruses.
Allen JD1, Jang H1, DiNapoli...Today, 03:49 AM -
Indian J Med Microbiol. 2018 Jul-Sep;36(3):401-407. doi: 10.4103/ijmm.IJMM_18_66.
Microbiological and chest X-ray studies on influenza B virus-associated pneumonia.
Wang X1, Tian Y1.
Author information
Abstract
Introduction:
The signs and symptoms of influenza B are commonly ignored. Therefore, very few clinical reports are available. This study is an attempt to evaluate the clinical features and characteristics of influenza B virus-associated pneumonia patients.
Objective:
The aim of this study is to investigate the microbiological and characteristics of influenza B virus-associated pneumonia patients.
Methodology:
Patients with <16 years old with a clinical diagnosis of influenza B virus infection and who had chest radiography within 2 days were enrolled. A total of 49 patients were categorised as the pneumonia group by clinical symptoms and chest X-ray (CXR) findings, whereas 107 patients were categorised as the non-pneumonia group based on the laboratory data and normal CXR findings.
Results:
The study observed that the age of the patients in the pneumonia group was significantly younger than the non-pneumonia group. The white blood cell (WBC) count of the pneumonia group was also higher. However, the haemoglobin (Hgb) level was lower in the pneumonia group. The C-reactive protein (CRP) level of the pneumonia group was also significantly high. The CXR findings revealed that 28.57% of patients had alveolar consolidation, 32.65% had interstitial infiltration and 40.82% had ground glass opacity.
Conclusions:
High clinical suspicion is required to detect pneumonia in influenza B virus patients. Based on the CXR findings, the study also suggests that patients with pleural effusion and positive bacterial culture need more attention for the severity of clinical outcome. Moreover, critical care should be given to paediatric patients having higher WBC count,...Today, 03:48 AM -
Front Microbiol. 2018 Oct 31;9:2596. doi: 10.3389/fmicb.2018.02596. eCollection 2018.
Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing.
Barbezange C1,2,3,4, Jones L2,3,4,5, Blanc H1,3, Isakov O6, Celniker G6, Enouf V2,3,4, Shomron N6, Vignuzzi M1,3, van...Today, 03:47 AM -
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unis Med. 2018 Jun;96(6):348-352. Influenza A/H1N1 pdm 09 in children's Hospital Bechir Hamza of Tunis.
Tinsa F, Barakizou H, Belhadj I, Fitouri Z, Borgi A, Samoud A, Ben Becher S, Ben Jabbalah N, Bouyahia O, Boussetta K.
Abstract
BACKGROUND:
Influenza A (H1N1) is a contagious acute...Today, 03:46 AM -
Psychol Health. 2018 Nov 15:1-19. doi: 10.1080/08870446.2018.1515436. [Epub ahead of print]
Trajectories of public psycho-behavioural responses relating to influenza A(H7N9) over the winter of 2014-15 in Hong Kong.
Liao Q1, Wu P2, Wing Tak Lam W1, Cowling BJ2, Fielding R1.
Author information
...Today, 03:45 AM -
Immunol Invest. 2018 Nov 15:1-12. doi: 10.1080/08820139.2018.1544640. [Epub ahead of print]
Immune Correlates of Protection Induced by Virus-Like Particles Containing 2009 H1N1 Pandemic Influenza HA, NA or M1 Proteins.
Moon EK1, Kang HJ2, Chu KB2, Lee SH2, Lee DH2, Soh Y3, Quan FS1,4. ...Today, 03:44 AM -
J Med Virol. 2018 Nov 15. doi: 10.1002/jmv.25358. [Epub ahead of print]
Umifenovir Susceptibility Monitoring and Characterization of Influenza Viruses Isolated during ARBITR Clinical Study.
Leneva IA1, Falynskova IN1, Makhmudova NR1, Poromov AA1,2, Yatsyshina SB3, Maleev VV3.
Author i
...Today, 03:44 AM -
PLoS One. 2018 Nov 15;13(11):e0206987. doi: 10.1371/journal.pone.0206987. eCollection 2018.
Influenza B viruses circulated during last 5 years in Mongolia.
Tsedenbal N1, Tsend-Ayush A2, Badarch D1, Jav S2, Pagbajab N1,3.
Author information
Abstract
Influenza...Today, 03:42 AM -
PLoS One. 2018 Nov 15;13(11):e0207431. doi: 10.1371/journal.pone.0207431. eCollection 2018.
A neuraminidase activity-based microneutralization assay for evaluating antibody responses to influenza H5 and H7 vaccines.
Zhao H1, Xu K1, Jiang Z1, Shao M1, Liu S1, Li X2,3, Wang J1, Li C1. ...Today, 03:42 AM -
Source: http://www.cidrap.umn.edu/news-persp...an-nov-16-2018
News Scan for Nov 16, 2018
More ground beef Salmonella cases; Salmonella turkey recall; New polio illnesses; More low-path H5N2 in Minnesota; Poultry biosecurity
Filed Under:
Salmonella; Foodborne Disease; Polio; Avian Influenza (Bird Flu); Agriculture Biosecurity
126 more people sickened with Salmonella after eating tainted beef
A...Yesterday, 05:02 PM -
Source: http://www.cidrap.umn.edu/news-persp...an-nov-16-2018
Stewardship / Resistance Scan for Nov 16, 2018
Improper prescribing in the ER; Hospital stewardship in China; Antibiotic use in Poland; Swiss AMR-related illness, deaths
Filed Under:
Antimicrobial Stewardship
Australian data show a third of emergency room antibiotics not needed
...Yesterday, 05:00 PM -
Source: http://www.cidrap.umn.edu/news-persp...ebola-hot-spot
Armed rebels kill UN peacekeepers in Ebola hot spot Filed Under: Ebola; VHF Lisa Schnirring | News Editor | CIDRAP News | Nov 16, 2018 A joint operation yesterday against armed rebels near the Democratic Republic of the Congo (DRC) Ebola hot spot in Beni killed seven United Na...Yesterday, 04:59 PM -
The first patient with autochthonous dengue in Catalonia is a young man from Barcelona
The first patient with autochthonous dengue in Catalonia is a young man residing in the north of the Barcelonès region, which is progressing favorably and was diagnosed on November 9, after suffering...Yesterday, 03:41 PM -
Confirmed 491 cases and 28 deaths due to influenza In the current season of influenza, 491 cases and 28 deaths have been confirmed, and the AH1N1 virus is the one that has prevailed so far, according to the weekly report of the General Directorate of Epidemiology (DGE) of the Ministry o...Yesterday, 03:17 PM
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Source: https://www.guampdn.com/story/news/2...ry/2022577002/ Chickenpox outbreak at Maria A. Ulloa Elementary School Jasmine Stole Weiss, Pacific Daily News Published 5:02 p.m. ChT Nov. 16, 2018 Seven Maria A. Ulloa Elementary School st...Yesterday, 02:52 PM
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Eggs: Spot prices are rising steadily
2018-11-15 14:10:00 Source: Huatai Futures
Spot tracking: Zhihua data shows that the national egg prices continue to rise slightly, trade monitoring shows that the receipt of goods is generally difficult, the goods are generally slow,...Yesterday, 06:01 AM -
Source: https://www.stuff.co.nz/timaru-heral...coccal-disease Timaru child admitted to hospital with meningococcal disease Rachael Comer17:28, Nov 15 2018 A 13-year-old Timaru girl is in Christchurch Hospital with meningococcal disease. South...November 15th, 2018, 09:47 PM
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Source: http://www.cidrap.umn.edu/news-persp...an-nov-15-2018
News Scan for Nov 15, 2018
More DRC Ebola cases; Promising new flu antiviral; Salmonella and restaurant grades
Filed Under:
Ebola; VHF; Influenza, General; Salmonella; Foodborne Disease
Three more Ebola cases, 1 death recorded in DRC
The Democratic Republic of the Congo's (DRC's)...November 15th, 2018, 06:14 PM -
Source: http://www.cidrap.umn.edu/news-persp...an-nov-15-2018
[B]Stewardship / Resistance Scan for Nov 15, 2018
Antibiotic use in Scotland; Drug-resistant malaria in India[/V]
Filed Under:
Antimicrobial Stewardship; Malaria
Scottish officials report human antibiotic use down slightly
Health Protection...November 15th, 2018, 06:09 PM -
Source: http://www.cidrap.umn.edu/news-persp...ial-use-europe
Surveys show wide range of antimicrobial use in Europe Filed Under: Antimicrobial Stewardship Lisa Schnirring | News Editor | CIDRAP News | Nov 15, 2018 A pair of studies today that provide a snapshot of antimicrobial consumption in European hospitals and nursing homes show that use varies widely by country, and that healthcare-associ...November 15th, 2018, 06:08 PM -
Source: https://www.wearegreenbay.com/news/l...ool/1599669360 Student Diagnosed with Tuberculosis at an Appleton High School By: Joshua Rose Posted: Nov 15, 2018 11:40 AM CST Updated: Nov 15, 2018 11:52 AM CST APPLETON, Wis. (WFRV) - An Appleton h...November 15th, 2018, 05:19 PM
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Source: http://www.nbc12.com/2018/11/15/dmv-...-tuberculosis/ DMV worker tests positive for tuberculosis By NBC12 Newsroom | November 15, 2018 at 3:02 PM EST - Updated November 15 at 3:02 PM RICHMOND, VA (WWBT) - An employee at the DMV office on Broad Street tested positive for...November 15th, 2018, 05:14 PM
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