Viral mechanisms

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Pathogenicity & virulence status

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Last Post: Cureus . Influenza B-Associated Acute Necrotizing Encephalopathy in a Previously Healthy Child: A Case Report of Fulminant Neurological Deterioration

2,683

2,940

Cureus . Influenza B-Associated Acute Necrotizing Encephalopathy in a Previously Healthy Child: A Case Report of Fulminant Neurological Deterioration

by tetano

Today, 01:51 AM

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Immune response (26/60)	Host binding ability (226/279)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (139/143)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 73 Posts: 171

Last Post: Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

171

Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

by tetano

December 13, 2025, 03:04 AM

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HA RBS (9/10)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 265 Posts: 279

Last Post: J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

265

279

J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

by tetano

March 27, 2026, 03:52 AM

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J Gen Virol . Y-Box-Binding Protein 3 (YBX3) Restricts Influenza A Virus by Interacting With Viral Ribonucleoprotein Complex and Imparing Its Function by tetano Started by tetano, June 20, 2020, 12:56 AM	0 responses 28 views 0 likes	Last Post by tetano June 20, 2020, 12:56 AM
Cell . Hybrid Gene Origination Creates Human-Virus Chimeric Proteins During Infection by tetano Started by tetano, June 20, 2020, 12:38 AM	0 responses 33 views 0 likes	Last Post by tetano June 20, 2020, 12:38 AM
Heliyon . Molecular Characterization and Three-Dimensional Structures of Avian H8, H11, H14, H15 and Swine H4 Influenza Virus Hemagglutinins by tetano Started by tetano, June 13, 2020, 01:33 AM	0 responses 29 views 0 likes	Last Post by tetano June 13, 2020, 01:33 AM
J Infect Quantifying the Importance of the Key Sites on Haemagglutinin in Determining the Selection Advantage of Influenza Virus: Using A/H3N2 as an Example by tetano Started by tetano, June 8, 2020, 04:09 AM	0 responses 32 views 0 likes	Last Post by tetano June 8, 2020, 04:09 AM
J Biomol Struct Dyn Cold and Distant: Structural Features of the Nucleoprotein Complex of a Cold-Adapted Influenza A Virus Strain by tetano Started by tetano, June 6, 2020, 02:44 AM	0 responses 26 views 0 likes	Last Post by tetano June 6, 2020, 02:44 AM
Sci Adv Structural Monitoring of a Transient Intermediate in the Hemagglutinin Fusion Machinery on Influenza Virions by tetano Started by tetano, June 6, 2020, 02:25 AM	0 responses 26 views 0 likes	Last Post by tetano June 6, 2020, 02:25 AM
Proc Natl Acad Sci U S A Membrane-tethered Mucin-Like Polypeptides Sterically Inhibit Binding and Slow Fusion Kinetics of Influenza A Virus by tetano Started by tetano, May 30, 2020, 01:03 AM	0 responses 31 views 0 likes	Last Post by tetano May 30, 2020, 01:03 AM
Nature Structural Transitions in Influenza Haemagglutinin at Membrane Fusion pH by tetano Started by tetano, May 30, 2020, 12:49 AM	0 responses 34 views 0 likes	Last Post by tetano May 30, 2020, 12:49 AM
PLoS One The Influenza Replication Blocking Inhibitor LASAG Does Not Sensitize Human Epithelial Cells for Bacterial Infections by tetano Started by tetano, May 20, 2020, 03:36 AM	0 responses 21 views 0 likes	Last Post by tetano May 20, 2020, 03:36 AM
A human cell polarity protein Lgl2 regulates influenza A virus nucleoprotein exportation from nucleus in MDCK cells by tetano Started by tetano, May 13, 2020, 03:00 AM	0 responses 21 views 0 likes	Last Post by tetano May 13, 2020, 03:00 AM

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