Viral mechanisms

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Pathogenicity & virulence status

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Last Post: Aging Cell . Virus-Induced Cellular Senescence Causes Pulmonary Sequelae Post-Influenza Infection

2,593

2,849

Aging Cell . Virus-Induced Cellular Senescence Causes Pulmonary Sequelae Post-Influenza Infection

by tetano

June 25, 2025, 04:01 AM

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Immune response (26/60)	Host binding ability (223/276)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (138/142)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 72 Posts: 170

Last Post: Elife . The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

170

Elife . The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

by tetano

May 29, 2024, 03:56 AM

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HA RBS (8/9)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 257 Posts: 271

Last Post: ACS Infect Dis . Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities

257

271

ACS Infect Dis . Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities

by tetano

March 16, 2025, 01:22 AM

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Vet Res . Host cellular protein RAB33B facilitates influenza viral replication and modulates M2 trafficking by enhancing autophagy by tetano Started by tetano, July 5, 2025, 03:00 AM	0 responses 13 views 0 likes	Last Post by tetano July 5, 2025, 03:00 AM
Sci Adv . Mitochondrial dysfunction enhances influenza pathogenesis by up-regulating de novo sialic acid biosynthesis by tetano Started by tetano, July 5, 2025, 02:35 AM	0 responses 10 views 0 likes	Last Post by tetano July 5, 2025, 02:35 AM
J Infect . Host lncRNA assists the nuclear import of influenza A virus protein PB2 in a species-specific manner by tetano Started by tetano, June 28, 2025, 05:23 AM	0 responses 18 views 0 likes	Last Post by tetano June 28, 2025, 05:23 AM
Microbiol Mol Biol Rev . Implications of morphological variation in influenza viruses by tetano Started by tetano, June 25, 2025, 04:06 AM	0 responses 12 views 0 likes	Last Post by tetano June 25, 2025, 04:06 AM
J Am Chem Soc . Structural Transition from Closed to Open for the Influenza A M2 Proton Channel as Observed by Proton-Detected Solid-State NMR by tetano Started by tetano, June 25, 2025, 04:06 AM	0 responses 12 views 0 likes	Last Post by tetano June 25, 2025, 04:06 AM
Biochemistry . Side Chain Structures of the Proton-Selective Histidine and Gating Tryptophan in Influenza BM2 Reveal Both Conservation and Variation of the Proton Conduction Mechanism by tetano Started by tetano, June 25, 2025, 03:40 AM	0 responses 8 views 0 likes	Last Post by tetano June 25, 2025, 03:40 AM
Virus Res . Characterization of Antigenically Dominant Regions in the Hemagglutinin Protein of B/Victoria-Lineage Influenza B Virus Using Monoclonal Antibody Escape Mutants by tetano Started by tetano, June 18, 2025, 02:09 AM	0 responses 11 views 0 likes	Last Post by tetano June 18, 2025, 02:09 AM
EMBO Rep . Regulated localization of transposable element RNA during influenza A virus infection by tetano Started by tetano, June 18, 2025, 02:08 AM	0 responses 10 views 0 likes	Last Post by tetano June 18, 2025, 02:08 AM
J Virol . IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency by tetano Started by tetano, June 14, 2025, 02:09 AM	0 responses 10 views 0 likes	Last Post by tetano June 14, 2025, 02:09 AM
Sci Adv . Influenza A virus subverts the LC3-pericentrin dynein adaptor complex for host cytoplasm entry by tetano Started by tetano, June 14, 2025, 02:07 AM	0 responses 9 views 0 likes	Last Post by tetano June 14, 2025, 02:07 AM

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