Viral mechanisms

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Pathogenicity & virulence status

1,348

1,150

Kleine-Levin syndrome elicited by encephalopathy with reversible splenial lesion

by tetano

August 15th, 2017, 11:57 PM

Sub-Forums:

Immune response (23/57)	Host binding ability (173/223)	Viral shedding (98/107)
Cytopathogenic effects with balance of replication & host contro (106/110)	Immunosurveillance escape via antigenic variation from immune response (14/14)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Molecular modeling studies demonstrate key mutations that could affect the ligand recognition by influenza AH1N1 neuraminidase

by tetano

October 28th, 2015, 03:00 AM

Sub-Forums:

HA � RBS (8/9)	HA - cleavage (3/62)	NA (6/6)
PB2 (11/34)	M gene (1/1)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Basic amino acids in the N-terminal half of the PB2 subunit of influenza virus RNA polymerase are involved in both transcription and replication

by tetano

May 24th, 2017, 12:24 AM

NS1 Information

148

162

Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site During Circulation in Humans

by tetano

Yesterday, 12:43 AM

Mark Channels Read

Topics	Statistics	Last Post
Epistatic Interactions within the Influenza A Virus Polymerase Complex Mediate Mutagen Resistance and Replication Fidelity Started by tetano, Yesterday, 12:42 AM	0 responses 4 views 0 likes	by tetano Yesterday, 12:42 AM
Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form Started by tetano, August 14th, 2017, 01:04 AM	0 responses 3 views 0 likes	by tetano August 14th, 2017, 01:04 AM
Palmitoylation contributes to membrane curvature in Influenza A virus assembly and hemagglutinin-mediated membrane fusion Started by tetano, August 14th, 2017, 12:50 AM	0 responses 1 view 0 likes	by tetano August 14th, 2017, 12:50 AM
Influenza virus recruits host protein kinase C to control assembly and activity of its replication machinery Started by tetano, August 1st, 2017, 11:34 PM	0 responses 2 views 0 likes	by tetano August 1st, 2017, 11:34 PM
Unexpected complexity in the interference activity of a cloned influenza defective interfering RNA Started by tetano, July 28th, 2017, 11:56 PM	0 responses 7 views 0 likes	by tetano July 28th, 2017, 11:56 PM
Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association Started by tetano, July 28th, 2017, 11:51 PM	0 responses 4 views 0 likes	by tetano July 28th, 2017, 11:51 PM
Mammalian Diaphanous-related formin-1 restricts early phases of influenza A/NWS/33 virus (H1N1) infection in LLC-MK2 cells by affecting cytoskeleton dynamics Started by tetano, July 28th, 2017, 11:39 PM	0 responses 3 views 0 likes	by tetano July 28th, 2017, 11:39 PM
Cholesterol is required for stability and infectivity of influenza A and respiratory syncytial viruses Started by tetano, July 28th, 2017, 11:14 PM	0 responses 4 views 0 likes	by tetano July 28th, 2017, 11:14 PM
Intracellular Colocalization of Influenza Viral RNA and Rab11A is Dependent upon Microtubule Filaments Started by tetano, July 22nd, 2017, 10:52 PM	0 responses 6 views 0 likes	by tetano July 22nd, 2017, 10:52 PM
Nucl.Ac.Res. Genome-wide analysis of influenza viral RNA and nucleoprotein association Started by tetano, July 13th, 2017, 08:58 AM	0 responses 16 views 0 likes	by tetano July 13th, 2017, 08:58 AM

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