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Viral mechanisms

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Pathogenicity & virulence status

Topics: 2,278 Posts: 2,525

Last Post: PLoS One . Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection

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2,525

PLoS One . Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection

by tetano

October 8, 2021, 11:36 PM

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Immune response (24/58)	Host binding ability (211/261)	Viral shedding (142/152)
Cytopathogenic effects with balance of replication & host contro (130/134)	Immunosurveillance escape via antigenic variation from immune response (33/33)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 71 Posts: 169

Last Post: Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

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Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

by tetano

April 8, 2020, 01:08 AM

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HA ? RBS (8/9)	HA - cleavage (3/62)	NA (6/6)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 56 Posts: 82

Last Post: Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice

Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice

by tetano

December 28, 2019, 01:23 AM

NS1 Information

Topics: 226 Posts: 240

Last Post: J Biomed Sci . Influenza a virus NS1 resembles a TRAF3-interacting motif to target the RNA sensing-TRAF3-type I IFN axis and impair antiviral innate immunity

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240

J Biomed Sci . Influenza a virus NS1 resembles a TRAF3-interacting motif to target the RNA sensing-TRAF3-type I IFN axis and impair antiviral innate immunity

by tetano

October 8, 2021, 11:42 PM

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J Infect . Characterization of key amino acid substitutions and dynamics of the influenza virus H3N2 hemagglutinin by tetano Started by tetano, October 13, 2021, 01:57 AM	0 responses 1 view 0 likes	Last Post by tetano October 13, 2021, 01:57 AM
An Pediatr (Engl Ed) . Influenza A (H1N1)pdm09 viral clearance kinetics in hospitalized children by tetano Started by tetano, October 6, 2021, 02:28 AM	0 responses 1 view 0 likes	Last Post by tetano October 6, 2021, 02:28 AM
J Gen Virol . Reduced sialidase activity of influenza A(H3N2) neuraminidase associated with positively charged amino acid substitutions by tetano Started by tetano, October 2, 2021, 02:15 AM	0 responses 1 view 0 likes	Last Post by tetano October 2, 2021, 02:15 AM
PLoS Pathog . Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity by tetano Started by tetano, September 29, 2021, 03:00 AM	0 responses 4 views 0 likes	Last Post by tetano September 29, 2021, 03:00 AM
Virus Res . Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein leve by tetano Started by tetano, September 26, 2021, 01:25 AM	0 responses 1 view 0 likes	Last Post by tetano September 26, 2021, 01:25 AM
Nat Microbiol . Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy by tetano Started by tetano, September 26, 2021, 01:22 AM	0 responses 2 views 0 likes	Last Post by tetano September 26, 2021, 01:22 AM
FEBS Lett . New structural insights into the multi-functional influenza A matrix protein 1 by tetano Started by tetano, September 22, 2021, 03:00 AM	0 responses 1 view 0 likes	Last Post by tetano September 22, 2021, 03:00 AM
Nat Commun . Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses by tetano Started by tetano, September 18, 2021, 12:30 AM	0 responses 1 view 0 likes	Last Post by tetano September 18, 2021, 12:30 AM
mBio . MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells by tetano Started by tetano, September 15, 2021, 02:58 AM	0 responses 1 view 0 likes	Last Post by tetano September 15, 2021, 02:58 AM
Virulence . Long noncoding RNA#45 exerts broad inhibitory effect on influenza a virus replication via its stem ring arms by tetano Started by tetano, September 15, 2021, 02:57 AM	0 responses 1 view 0 likes	Last Post by tetano September 15, 2021, 02:57 AM

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