Viral mechanisms

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Pathogenicity & virulence status

Topics: 2,682 Posts: 2,939

Last Post: J Virol . Influenza A virus infection induces initial proliferation of commensal Streptococcus pneumoniae in the larynx leading to dissemination into the lower respiratory tract

2,682

2,939

J Virol . Influenza A virus infection induces initial proliferation of commensal Streptococcus pneumoniae in the larynx leading to dissemination into the lower respiratory tract

by tetano

July 1, 2026, 05:21 AM

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Immune response (26/60)	Host binding ability (226/279)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (139/143)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 73 Posts: 171

Last Post: Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

171

Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

by tetano

December 13, 2025, 03:04 AM

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HA RBS (9/10)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 265 Posts: 279

Last Post: J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

265

279

J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

by tetano

March 27, 2026, 03:52 AM

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J Med Virol . Influenza A Virus Induces Autophagosome by Inhibiting LTCC/Calpain 2/LC3A Signaling to Promote Viral Replication by tetano Started by tetano, May 14, 2025, 04:03 AM	0 responses 22 views 0 likes	Last Post by tetano May 14, 2025, 04:03 AM
Microbiol Mol Biol Rev . Viral factors underlying the pandemic potential of influenza viruses by tetano Started by tetano, May 10, 2025, 03:18 AM	0 responses 19 views 0 likes	Last Post by tetano May 10, 2025, 03:18 AM
Nat Commun . Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface by tetano Started by tetano, May 2, 2025, 01:28 AM	0 responses 20 views 0 likes	Last Post by tetano May 2, 2025, 01:28 AM
Npj Viruses . Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites by tetano Started by tetano, May 2, 2025, 01:13 AM	0 responses 19 views 0 likes	Last Post by tetano May 2, 2025, 01:13 AM
Virus Res . JNK kinase promotes inflammatory responses by inducing the expression of the inflammatory amplifier TREM1 during influenza a virus infection by tetano Started by tetano, April 23, 2025, 01:40 AM	0 responses 18 views 0 likes	Last Post by tetano April 23, 2025, 01:40 AM
iScience . Somatic Miwi2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis by tetano Started by tetano, April 19, 2025, 03:21 AM	0 responses 31 views 0 likes	Last Post by tetano April 19, 2025, 03:21 AM
Proc Natl Acad Sci U S A . Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryoelectron tomography by tetano Started by tetano, April 19, 2025, 03:18 AM	0 responses 27 views 0 likes	Last Post by tetano April 19, 2025, 03:18 AM
Nucleic Acids Res . Nuclear AGO2 supports influenza A virus replication through type-I interferon regulation by tetano Started by tetano, April 16, 2025, 02:48 AM	0 responses 35 views 0 likes	Last Post by tetano April 16, 2025, 02:48 AM
J Virol . Cell binding, uptake, and infection of influenza A virus using recombinant antibody-based receptors by tetano Started by tetano, April 12, 2025, 01:33 AM	0 responses 33 views 0 likes	Last Post by tetano April 12, 2025, 01:33 AM
J Am Chem Soc . Integrating Cryo-Electron Microscopy and Molecular Dynamics Simulations to Investigate Membrane Binding of Influenza Virus Fusion Peptides by tetano Started by tetano, April 12, 2025, 01:21 AM	0 responses 22 views 0 likes	Last Post by tetano April 12, 2025, 01:21 AM

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