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J Cardiothorac Surg
. 2024 Aug 24;19(1):492.
doi: 10.1186/s13019-024-02997-0. Fulminant myocarditis caused by influenza B virus in a male child: a case report and literature review
Fei Tian # 1 2 , Yi Xiao # 3 , Zhekang Peng # 1 , Lingyun Zhang 4 , Fu Ni 5 , Shengmin Gui 5 2 , Yuqing Fan 5 , Zuyang Xi 6 7 , Zhaohui Zhang 8
Affiliations
Background: Influenza B virus induced myocarditis is a rare complication with potentially wide variations in severity and clinical presentation, and the pathogenesis is unclear.
Case presentation: We describe a rare case of a 7-year-old boy who developed fulminant myocarditis (FM) due to influenza B virus infection. Treatment measures included mechanical ventilation, vasoactive agents, Extracorporeal membrane oxygenation (ECMO), Continuous Renal Replacement Therapy (CRRT), anti-inflammatory, antiviral, anti-infection, and enteral nutrition support. After 10 days of treatment, the patient succumbed to multiorgan failure.
Conclusions: After a systematic review of the literature, we found that this disease predominantly affects females, with pediatric cases exceedingly rare. Fulminant myocarditis (FM) progresses rapidly, poses significant treatment challenges sporadic, and carries a poor prognosis. Interestingly, literature reports suggest that anti-thymocyte globulin therapy may have a positive impact in treating FM, potentially offering new insights into its pathogenesis and clinical management.
Keywords: Fulminant myocarditis; Influenza B virus; Myocarditis; Viral myocarditis.
. 2024 Aug 24;19(1):492.
doi: 10.1186/s13019-024-02997-0. Fulminant myocarditis caused by influenza B virus in a male child: a case report and literature review
Fei Tian # 1 2 , Yi Xiao # 3 , Zhekang Peng # 1 , Lingyun Zhang 4 , Fu Ni 5 , Shengmin Gui 5 2 , Yuqing Fan 5 , Zuyang Xi 6 7 , Zhaohui Zhang 8
Affiliations
- PMID: 39182151
- DOI: 10.1186/s13019-024-02997-0
Background: Influenza B virus induced myocarditis is a rare complication with potentially wide variations in severity and clinical presentation, and the pathogenesis is unclear.
Case presentation: We describe a rare case of a 7-year-old boy who developed fulminant myocarditis (FM) due to influenza B virus infection. Treatment measures included mechanical ventilation, vasoactive agents, Extracorporeal membrane oxygenation (ECMO), Continuous Renal Replacement Therapy (CRRT), anti-inflammatory, antiviral, anti-infection, and enteral nutrition support. After 10 days of treatment, the patient succumbed to multiorgan failure.
Conclusions: After a systematic review of the literature, we found that this disease predominantly affects females, with pediatric cases exceedingly rare. Fulminant myocarditis (FM) progresses rapidly, poses significant treatment challenges sporadic, and carries a poor prognosis. Interestingly, literature reports suggest that anti-thymocyte globulin therapy may have a positive impact in treating FM, potentially offering new insights into its pathogenesis and clinical management.
Keywords: Fulminant myocarditis; Influenza B virus; Myocarditis; Viral myocarditis.