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Influenza virus B-associated hemophagocytic lymphohistiocytosis

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  • Influenza virus B-associated hemophagocytic lymphohistiocytosis


    Hematol Rep. 2019 Sep 18;11(3):8268. doi: 10.4081/hr.2019.8268. eCollection 2019 Sep 18. Influenza virus B-associated hemophagocytic lymphohistiocytosis.

    Gao J1, Pasion J2, Sanchez-Petitto G3, Law J3.
    Author information

    1 Department of Medicine. 2 Department of Pathology, University of Maryland School of Medicine, Baltimore, MD. 3 University of Maryland School of Medicine, Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.

    Abstract

    This original report describes the diagnosis and management of a male with hemophagocytic lymphohistiocytosis (HLH) triggered by influenza B virus infection. The patient was diagnosed with HLH- 2004 clinical criteria and a bone marrow biopsy demonstrating hemophagocytes. Therapy consisted of etoposide and dexamethasone while monitoring hemoglobin and platelet levels. To enable early recognition and prompt treatment for this disease, physicians should be aware of this association.
    ?Copyright: the Author(s), 2019.


    KEYWORDS:

    Hemophagocytic Lymphohistiocytosis; Influenza B virus; hemophagocyte

    PMID: 31579142 PMCID: PMC6761467 DOI: 10.4081/hr.2019.8268

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