Influenza Other Respir Viruses. 2014 Nov 10. doi: 10.1111/irv.12296. [Epub ahead of print]
Case series of rash associated with influenza B in school children.
Skowronski DM1, Chambers C, Osei W, Walker J, Petric M, Naus M, Li Y, Krajden M.
Author information
Abstract
This case series describes morbilliform and other rash presentations among schoolchildren during a March 2014 outbreak of influenza-like illness (ILI) in British Columbia, Canada. Multiplex nucleic acid testing of nasopharyngeal specimens and paired serologic investigations identified that influenza B, characterized as B/Massachusetts/02/2012-like (Yamagata-lineage), was the only viral aetiology and most likely cause of ILI and rash. An association between influenza B and rash has been described infrequently elsewhere, and not previously in North America. Influenza B should be considered in the differential diagnosis of febrile exanthem. Evaluation of the nature, incidence and contributing agent-host-environment interactions, and immunologic mechanisms to possibly explain influenza-associated rash is warranted.
? 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
KEYWORDS:
Exanthem; inactivated; influenza; influenza vaccine; influenza-like illness; morbilliform; rash; vaccine
PMID:
25382064
[PubMed - as supplied by publisher]
Case series of rash associated with influenza B in school children.
Skowronski DM1, Chambers C, Osei W, Walker J, Petric M, Naus M, Li Y, Krajden M.
Author information
Abstract
This case series describes morbilliform and other rash presentations among schoolchildren during a March 2014 outbreak of influenza-like illness (ILI) in British Columbia, Canada. Multiplex nucleic acid testing of nasopharyngeal specimens and paired serologic investigations identified that influenza B, characterized as B/Massachusetts/02/2012-like (Yamagata-lineage), was the only viral aetiology and most likely cause of ILI and rash. An association between influenza B and rash has been described infrequently elsewhere, and not previously in North America. Influenza B should be considered in the differential diagnosis of febrile exanthem. Evaluation of the nature, incidence and contributing agent-host-environment interactions, and immunologic mechanisms to possibly explain influenza-associated rash is warranted.
? 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
KEYWORDS:
Exanthem; inactivated; influenza; influenza vaccine; influenza-like illness; morbilliform; rash; vaccine
PMID:
25382064
[PubMed - as supplied by publisher]