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Virulence. 2013 Nov 19;5(1). [Epub ahead of print]
The complex link between influenza and severe sepsis.
Florescu DF, Kalil AC.
Source
Infectious Diseases Division; Internal Medicine Department; University of Nebraska Medical Center; Omaha, NE USA.
Abstract
Severe sepsis is traditionally associated with bacterial diseases. While fungi and parasites can also cause sepsis, they are significantly less common than bacterial causes. However, viruses are becoming a growing cause of severe sepsis worldwide. Among these viruses, influenza is crossing all geographic boundaries and is causing larger epidemics and pandemics. As a consequence, more critically ill patients with severe sepsis caused directly by influenza viruses, or indirectly by influenza-induced secondary bacterial infections are being admitted to hospitals worldwide. This manuscript aims to provide a pathophysiological and clinical update on the link between influenza and severe sepsis.
KEYWORDS:
infection, influenza, sepsis, severe sepsis, viral
PMID:
24253109
[PubMed - as supplied by publisher]
Free full text
The complex link between influenza and severe sepsis.
Florescu DF, Kalil AC.
Source
Infectious Diseases Division; Internal Medicine Department; University of Nebraska Medical Center; Omaha, NE USA.
Abstract
Severe sepsis is traditionally associated with bacterial diseases. While fungi and parasites can also cause sepsis, they are significantly less common than bacterial causes. However, viruses are becoming a growing cause of severe sepsis worldwide. Among these viruses, influenza is crossing all geographic boundaries and is causing larger epidemics and pandemics. As a consequence, more critically ill patients with severe sepsis caused directly by influenza viruses, or indirectly by influenza-induced secondary bacterial infections are being admitted to hospitals worldwide. This manuscript aims to provide a pathophysiological and clinical update on the link between influenza and severe sepsis.
KEYWORDS:
infection, influenza, sepsis, severe sepsis, viral
PMID:
24253109
[PubMed - as supplied by publisher]
Free full text
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