Viral mechanisms

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Pathogenicity & virulence status

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Last Post: Eurosurv. Severe A(H1N1)pdm09 influenza acute encephalopathy outbreak in children in Tuscany, Italy, December 2023 to January 2024

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2,755

Eurosurv. Severe A(H1N1)pdm09 influenza acute encephalopathy outbreak in children in Tuscany, Italy, December 2023 to January 2024

by tetano

Today, 12:49 AM

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Immune response (26/60)	Host binding ability (221/271)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (133/137)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 71 Posts: 169

Last Post: Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

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Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

by tetano

April 8, 2020, 01:08 AM

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HA RBS (8/9)	HA - cleavage (3/62)	NA (6/6)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 251 Posts: 265

Last Post: J Virol . Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

251

265

J Virol . Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

by tetano

April 20, 2024, 02:19 AM

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Towards a structural understanding of RNA synthesis by negative strand RNA viral polymerases by tetano Started by tetano, February 3, 2016, 02:21 AM	0 responses 20 views 0 likes	Last Post by tetano February 3, 2016, 02:21 AM
DDX3 interacts with influenza A NS1 and NP proteins and exerts antiviral function through regulation of stress granule formation by tetano Started by tetano, January 27, 2016, 01:57 AM	0 responses 33 views 0 likes	Last Post by tetano January 27, 2016, 01:57 AM
Codon deletions in the influenza A virus PA gene generate temperature-sensitive viruses by tetano Started by tetano, January 27, 2016, 01:56 AM	0 responses 17 views 0 likes	Last Post by tetano January 27, 2016, 01:56 AM
Influenza virus and the chromatin: Role of CHD1 chromatin remodeler on virus life cycle by tetano Started by tetano, January 27, 2016, 01:55 AM	0 responses 19 views 0 likes	Last Post by tetano January 27, 2016, 01:55 AM
Autophagy is involved in regulating influenza A virus RNA and protein synthesis associated with both modulation of Hsp90 induction and mTOR/p70S6K signaling pathway by tetano Started by tetano, January 27, 2016, 01:50 AM	0 responses 29 views 0 likes	Last Post by tetano January 27, 2016, 01:50 AM
Replication-Competent Influenza A and B Viruses Expressing a Fluorescent Dynamic Timer Protein for In Vitro and In Vivo Studies by tetano Started by tetano, January 27, 2016, 12:56 AM	0 responses 13 views 0 likes	Last Post by tetano January 27, 2016, 12:56 AM
Coupling high-throughput genetics with phylogenetic information reveals an epistatic interaction on the influenza A virus M segment by tetano Started by tetano, January 16, 2016, 03:14 AM	0 responses 12 views 0 likes	Last Post by tetano January 16, 2016, 03:14 AM
Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN by tetano Started by tetano, January 16, 2016, 02:33 AM	0 responses 10 views 0 likes	Last Post by tetano January 16, 2016, 02:33 AM
Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins by tetano Started by tetano, January 13, 2016, 01:59 AM	0 responses 19 views 0 likes	Last Post by tetano January 13, 2016, 01:59 AM
Research Progress in the Function of SUMOylation during Infection by the Influenza Virus by tetano Started by tetano, January 9, 2016, 04:38 AM	0 responses 16 views 0 likes	Last Post by tetano January 9, 2016, 04:38 AM

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