Viral mechanisms

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Pathogenicity & virulence status

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Last Post: Front Pediatr . A case report and literature review on tocilizumab-cured acute necrotizing encephalopathy caused by influenza A virus

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Front Pediatr . A case report and literature review on tocilizumab-cured acute necrotizing encephalopathy caused by influenza A virus

by tetano

Today, 02:21 AM

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Immune response (26/60)	Host binding ability (221/271)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (133/137)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

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Last Post: Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

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Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

by tetano

April 8, 2020, 01:08 AM

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HA RBS (8/9)	HA - cleavage (3/62)	NA (6/6)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

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Last Post: J Virol . Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

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265

J Virol . Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

by tetano

April 20, 2024, 02:19 AM

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Functional studies reveal the similarities and differences between AM2 and BM2 proton channels from influenza viruses by tetano Started by tetano, November 8, 2017, 03:11 AM	0 responses 14 views 0 likes	Last Post by tetano November 8, 2017, 03:11 AM
NMR spectra of PB2 627, the RNA-binding domain in influenza A virus RNA polymerase that contains the pathogenicity factor lysine 627, and improvement of the spectra by small osmolytes by tetano Started by tetano, November 4, 2017, 01:43 AM	0 responses 15 views 0 likes	Last Post by tetano November 4, 2017, 01:43 AM
KIF13A mediates influenza a virus ribonucleoproteins trafficking by tetano Started by tetano, October 28, 2017, 01:26 AM	0 responses 23 views 0 likes	Last Post by tetano October 28, 2017, 01:26 AM
Cellular splicing factor UAP56 stimulates trimeric NP formation for assembly of functional influenza viral ribonucleoprotein complexes by tetano Started by tetano, October 28, 2017, 01:03 AM	0 responses 18 views 0 likes	Last Post by tetano October 28, 2017, 01:03 AM
RNA structure interactions and ribonucleoprotein processes of the influenza A virus by tetano Started by tetano, October 21, 2017, 01:47 AM	0 responses 24 views 0 likes	Last Post by tetano October 21, 2017, 01:47 AM
Mutations in the Influenza A virus M1 protein enhance virus budding to complement lethal mutations in the M2 cytoplasmic tail by tetano Started by tetano, October 21, 2017, 01:28 AM	0 responses 19 views 0 likes	Last Post by tetano October 21, 2017, 01:28 AM
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs by tetano Started by tetano, October 14, 2017, 01:27 AM	0 responses 13 views 0 likes	Last Post by tetano October 14, 2017, 01:27 AM
Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication by tetano Started by tetano, September 30, 2017, 01:49 AM	0 responses 28 views 0 likes	Last Post by tetano September 30, 2017, 01:49 AM
Influenza Pathogenesis in Genetically Defined Resistant and Susceptible Murine Strains by tetano Started by tetano, September 30, 2017, 01:43 AM	0 responses 26 views 0 likes	Last Post by tetano September 30, 2017, 01:43 AM
Influenza A Virus Studies in a Mouse Model of Infection by tetano Started by tetano, September 23, 2017, 01:38 AM	0 responses 25 views 0 likes	Last Post by tetano September 23, 2017, 01:38 AM

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