Viral mechanisms

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Pathogenicity & virulence status

Topics: 2,651 Posts: 2,908

Last Post: Front Neurol . Clinical features, prognostic factors of pediatric acute necrotizing encephalopathy: a 67-case retrospective analysis

2,651

2,908

Front Neurol . Clinical features, prognostic factors of pediatric acute necrotizing encephalopathy: a 67-case retrospective analysis

by tetano

March 14, 2026, 03:55 AM

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Immune response (26/60)	Host binding ability (226/279)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (139/143)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 73 Posts: 171

Last Post: Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

171

Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

by tetano

December 13, 2025, 03:04 AM

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HA RBS (9/10)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 264 Posts: 278

Last Post: Virus Genes . Screening for influenza B virus NS1-interacting host proteins and characterization of interactions with hnRNPA0 and DDX39B

264

278

Virus Genes . Screening for influenza B virus NS1-interacting host proteins and characterization of interactions with hnRNPA0 and DDX39B

by tetano

March 14, 2026, 03:49 AM

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Front Mol Biosci . pH-Dependent Mechanisms of Influenza Infection Mediated by Hemagglutinin by tetano Started by tetano, January 5, 2022, 03:01 AM	0 responses 52 views 0 likes	Last Post by tetano January 5, 2022, 03:01 AM
Virulence . The battle for autophagy between host and influenza A virus by tetano Started by tetano, January 1, 2022, 03:45 AM	0 responses 27 views 0 likes	Last Post by tetano January 1, 2022, 03:45 AM
Pathogens . Structural Requirements in the Hemagglutinin Cleavage Site-Coding RNA Region for the Generation of Highly Pathogenic Avian Influenza Virus by tetano Started by tetano, December 29, 2021, 04:27 AM	0 responses 35 views 0 likes	Last Post by tetano December 29, 2021, 04:27 AM
Viruses . Comparative Susceptibility of Madin-Darby Canine Kidney (MDCK) Derived Cell Lines for Isolation of Swine Origin Influenza A Viruses from Different Clinical Specimens by tetano Started by tetano, December 29, 2021, 04:21 AM	0 responses 24 views 0 likes	Last Post by tetano December 29, 2021, 04:21 AM
J Virol . The host factor ANP32A is required for influenza A virus vRNA and cRNA synthesis by tetano Started by tetano, December 26, 2021, 02:38 AM	0 responses 43 views 0 likes	Last Post by tetano December 26, 2021, 02:38 AM
CRISPR J . Porcine Genome-Wide CRISPR Screen Identifies the Golgi Apparatus Complex Protein COG8 as a Pivotal Regulator of Influenza Virus Infection by tetano Started by tetano, December 26, 2021, 02:38 AM	0 responses 54 views 0 likes	Last Post by tetano December 26, 2021, 02:38 AM
Front Immunol . Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice by tetano Started by tetano, December 22, 2021, 03:21 AM	0 responses 55 views 0 likes	Last Post by tetano December 22, 2021, 03:21 AM
Virus Res . Downregulation of calcium-regulated heat stable protein 1 expression by low-temperature stimulation causes reduction of interferon-β expression and sensitivity to influenza viral infection by tetano Started by tetano, December 22, 2021, 03:17 AM	0 responses 46 views 0 likes	Last Post by tetano December 22, 2021, 03:17 AM
Mol Microbiol . Non-classical autophagy activation pathways are essential for production of infectious Influenza A virus in vitro by tetano Started by tetano, December 22, 2021, 03:09 AM	0 responses 41 views 0 likes	Last Post by tetano December 22, 2021, 03:09 AM
J Virol . SUMOylation of matrix protein M1 and filamentous morphology collectively contribute to the replication and virulence of highly pathogenic H5N1 avian influenza viruses in mammals by tetano Started by tetano, December 18, 2021, 03:26 AM	0 responses 38 views 0 likes	Last Post by tetano December 18, 2021, 03:26 AM

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