Viral mechanisms

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Pathogenicity & virulence status

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Last Post: Influenza Other Respir Viruses . Neurologic Complications of Influenza and Potential Protective Vaccine Effects

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2,831

Influenza Other Respir Viruses . Neurologic Complications of Influenza and Potential Protective Vaccine Effects

by tetano

March 8, 2025, 05:34 AM

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Immune response (26/60)	Host binding ability (223/276)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (136/140)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 72 Posts: 170

Last Post: Elife . The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

170

Elife . The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

by tetano

May 29, 2024, 03:56 AM

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HA RBS (8/9)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 257 Posts: 271

Last Post: ACS Infect Dis . Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities

257

271

ACS Infect Dis . Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities

by tetano

Today, 01:22 AM

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Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airway by tetano Started by tetano, April 22, 2020, 01:07 AM	0 responses 23 views 0 likes	Last Post by tetano April 22, 2020, 01:07 AM
PLoS Comput Biol. A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract by tetano Started by tetano, April 15, 2020, 03:56 AM	0 responses 26 views 0 likes	Last Post by tetano April 15, 2020, 03:56 AM
Nonproteolytic K29-Linked Ubiquitination of the PB2 Replication Protein of Influenza A Viruses by Proviral Cullin 4-Based E3 Ligases by tetano Started by tetano, April 10, 2020, 11:46 PM	0 responses 25 views 0 likes	Last Post by tetano April 10, 2020, 11:46 PM
Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV)-Reduced Virus Fitness in Chickens is Restored by Reassortment with Highly Pathogenic H5N1 AIV by tetano Started by tetano, April 4, 2020, 01:35 AM	0 responses 29 views 0 likes	Last Post by tetano April 4, 2020, 01:35 AM
Deficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells by tetano Started by tetano, March 28, 2020, 02:27 AM	0 responses 40 views 0 likes	Last Post by tetano March 28, 2020, 02:27 AM
H1N1 Infection Reduces Glucose Level in Human U937 Monocytes Culture by tetano Started by tetano, March 25, 2020, 03:11 AM	0 responses 21 views 0 likes	Last Post by tetano March 25, 2020, 03:11 AM
Influenza hemagglutinin drives viral entry via two sequential intramembrane mechanisms by tetano Started by tetano, March 21, 2020, 01:13 AM	0 responses 32 views 0 likes	Last Post by tetano March 21, 2020, 01:13 AM
Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation by tetano Started by tetano, March 14, 2020, 01:45 AM	0 responses 45 views 0 likes	Last Post by tetano March 14, 2020, 01:45 AM
R195K mutation in the PA-X protein increases the virulence and transmission of influenza A virus in mammalian hosts by tetano Started by tetano, March 14, 2020, 01:29 AM	0 responses 36 views 0 likes	Last Post by tetano March 14, 2020, 01:29 AM
Comprehensive characterisation of transcriptional activity during influenza A virus infection reveals biases in cap-snatching of host RNA sequences by tetano Started by tetano, March 14, 2020, 01:28 AM	0 responses 28 views 0 likes	Last Post by tetano March 14, 2020, 01:28 AM

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