Viral mechanisms

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Pathogenicity & virulence status

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Last Post: Eurosurv. Severe A(H1N1)pdm09 influenza acute encephalopathy outbreak in children in Tuscany, Italy, December 2023 to January 2024

2,506

2,756

Eurosurv. Severe A(H1N1)pdm09 influenza acute encephalopathy outbreak in children in Tuscany, Italy, December 2023 to January 2024

by sharon sanders

Today, 06:50 AM

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Immune response (26/60)	Host binding ability (221/271)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (133/137)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 71 Posts: 169

Last Post: Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

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Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection

by tetano

April 8, 2020, 01:08 AM

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HA RBS (8/9)	HA - cleavage (3/62)	NA (6/6)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 251 Posts: 265

Last Post: J Virol . Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

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265

J Virol . Influenza A virus NS1 effector domain is required for PA-X-mediated host shutoff in infected cells

by tetano

April 20, 2024, 02:19 AM

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Energetics of β-turn formation in a mutant peptide YPGDV from influenza hemagglutinin: an MD simulation study by tetano Started by tetano, October 5, 2013, 01:07 AM	0 responses 183 views 0 likes	Last Post by tetano October 5, 2013, 01:07 AM
A comprehensive map of the influenza A virus replication cycle by tetano Started by tetano, October 5, 2013, 12:55 AM	0 responses 176 views 0 likes	Last Post by tetano October 5, 2013, 12:55 AM
Highly sensitive real-time in vivo imaging of an influenza reporter virus reveals dynamics of replication and spread by tetano Started by tetano, October 5, 2013, 12:47 AM	0 responses 148 views 0 likes	Last Post by tetano October 5, 2013, 12:47 AM
Spherical influenza viruses have a fitness advantage in embryonated eggs, while filament-producing strains are selected in vivo by tetano Started by tetano, October 5, 2013, 12:46 AM	0 responses 129 views 0 likes	Last Post by tetano October 5, 2013, 12:46 AM
Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells by tetano Started by tetano, September 28, 2013, 01:41 AM	0 responses 158 views 0 likes	Last Post by tetano September 28, 2013, 01:41 AM
The configuration of viral ribonucleoprotein complexes within the influenza A virion by tetano Started by tetano, September 28, 2013, 12:51 AM	0 responses 137 views 0 likes	Last Post by tetano September 28, 2013, 12:51 AM
The Crystal Structure and RNA-Binding of an Orthomyxovirus Nucleoprotein by tetano Started by tetano, September 28, 2013, 12:44 AM	0 responses 120 views 0 likes	Last Post by tetano September 28, 2013, 12:44 AM
Exploring Histidine Conformations in the M2 Channel Lumen of the Influenza A Virus at Neutral pH via Molecular Simulations by tetano Started by tetano, September 28, 2013, 12:35 AM	0 responses 136 views 0 likes	Last Post by tetano September 28, 2013, 12:35 AM
Reverse genetics platform construction of influenza pandemic virus strain by tetano Started by tetano, September 25, 2013, 02:31 AM	1 response 163 views 0 likes	Last Post by gsgs September 25, 2013, 09:48 AM
Multiphasic effects of cholesterol on influenza fusion kinetics reflect multiple mechanistic roles by tetano Started by tetano, September 25, 2013, 02:01 AM	0 responses 91 views 0 likes	Last Post by tetano September 25, 2013, 02:01 AM

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