MIR Journal is an international resource for academic researchers in virology, bacteriology, and mycology as well as for professionals in the pharmaceutical and biopharmaceutical industry. 

Microbiology Independent Research Journal
Volume 2, Number 1, 2015
Mutations in human genes that increase the risk for severe influenza infection


O. I. Kiselev1 , A. B. Komissarov1 , O.S.Konshina1# , M.N.Dmitrieva1 , E.G.Deyeva1 , T.V.Sologub1 , V.I.Pokrovskiy2
Author Affiliations

1 Research Institute of Influenza, Saint Petersburg, Russian Federation
2 Central Research Institute of Epidemiology, Moscow, Russian Federation
# Corresponding author: Olga Konshina, 197376, St. Petersburg, Prof. Popova str., 15/17, E-mail: olga_konshina@influenza.spb.ru

Abstract

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The system of genetic control of innate immune responses to influenza infection and gene function allows for the development of systemic treatment of influenza with a focus on the phenotype of mutations based on individual genetic susceptibility to severe disease and/or the development of complications.
Full text is at the link. If I'm reading this right, Japan and China are much more vulnerable to severe influenza than northern Europe and England.