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  • sharon sanders
    replied
    Please see:

    Discussion - Monkeypox vaccine

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  • sharon sanders
    replied
    bump this

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  • Shiloh
    replied
    Source: https://www.startribune.com/minnesot...ted/600196968/

    Minnesota flight attendant with monkeypox symptoms says she struggled to get tested
    Clinicians don't need approval before sending samples for monkeypox testing, but must be careful to collect useable specimens, state advises.
    By Jeremy Olson Star Tribune
    August 9, 2022 — 3:25pm

    Joan Sullivan has cold symptoms and pimple-like rashes on her body, and zero idea yet whether it is all because of monkeypox.

    The 29-year-old Minneapolis flight attendant struggled for five days to seek testing from the Minnesota Department of Health and two designated clinics in the Twin Cities. While clinics are urging testing for men who have sex with other men — the risk group making up almost all of the state's 55 known infections — Sullivan said she worries this focus could miss possible cases like hers that fall outside the norm...

    ...The Red Door Clinic in Minneapolis and Clinic 555 in St. Paul were promoted last week as testing locations to provide easy and familiar access to the primary risk group of men who have sex with other men. However, any clinician can swab rashes on suspect patients and send the samples to the state public health lab or commercial labs such as Mayo Clinic for results.

    ..After failing since Thursday to reach anyone at Red Door or Clinic 555 to schedule testing, Sullivan went on Monday to her primary care clinic. A provider swabbed lesions and sent the specimens to the state lab, with results expected almost a week after she first sought testing. She received a call from the Red Door Clinic later that day...

    ...Sullivan said she wonders if she was infected while working on recent flights to England or California, or during long layovers. One person in her close social network has reported symptoms as well, though.

    "Everyone in the bubble has kind of locked into their own home until we figure out who are the sick ones," said Sullivan, who first experienced symptoms two weeks ago and took a COVID-19 test, which was negative.

    A week into her illness, Sullivan started complaining about the "worst acne flareup in years," she said. A sexual partner, who works as a paramedic, suggested it could be monkeypox. In her isolation, Sullivan has entertained herself and others with TikTok videos, including one on the mittens and other strategies to stop scratching her rashes. One update netted 130,000 views...

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  • Pathfinder
    replied
    Translation Google

    Monkeypox. Primates suspected of having a link to the disease have been attacked in Brazil

    The WHO deplored this Tuesday, August 9, 2022 that monkeys, suspected of spreading smallpox of the same name, were attacked in Brazil. The organization recalls that the current epidemic of “monkeypox” is not linked to animals.

    Ouest France
    with AFP.
    Published on 08/09/2022 at 6:02 p.m.

    The World Health Organization assured this Tuesday, August 9, 2022 that the monkeypox epidemic raging around the world is not linked to these animals, deploring that primates could have been attacked in Brazil.

    "People need to know that the transmission we're seeing now is between humans ," WHO spokeswoman Margaret Harris told a regular press briefing in Geneva.

    Poisoned monkeys in Brazil

    She was being questioned about reports of attacks on monkeys in Brazil. The Brazilian news site G1 reported that a dozen were poisoned, and some injured, in less than a week in a nature reserve in Rio do Preto, in the state of Sao Paulo.

    Others were stoned or chased or poisoned in different Brazilian cities, according to G1, which quotes the association for the fight against illegal wildlife trafficking Renctas.

    Brazil has reported more than 1,700 cases and one death, according to WHO statistics. Worldwide, more than 28,100 cases and 12 deaths have been reported.

    Monkeypox virus present in many species

    The term monkeypox was used when this virus was discovered in 1958 in monkeys in a laboratory in Denmark, but the virus has been demonstrated in different animal species, especially rodents. The first human case was detected in 1970 in the Democratic Republic of Congo (DRC).

    This virus can be transmitted from animals to humans, but the recent explosion in cases worldwide is due to transmission between humans during close contact, said Margaret Harris.

    People "definitely shouldn't prey on animals," she said, stressing that the best way to curb the spread of the virus was to recognize the symptoms, get help from a doctor and to take "precautions to prevent transmission".

    Do not stigmatize infected people

    The group most affected by the epidemic are men who have sex with men. The WHO calls not to stigmatize infected people.

    Are you planning to get vaccinated against monkeypox?

    “Any stigma […] will increase transmission, because if people are afraid to say they are infected, they will not seek treatment and take precautions ,” said Margaret Harris.
    ...

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  • sharon sanders
    replied

    Former FDA Commissioner: U.S. Can Still 'Catch Up' On Monkeypox


    “I think there’s a potential to get this back in the box, but it’s going to be very difficult," Scott Gottlieb said Sunday.
    Aug 8, 2022, 12:27 AM EDT


    snip

    Gottlieb had previously said the U.S. had probably failed to contain monkeypox after stumbling during its initial efforts to address the virus when the first case was reported in the country in May. He said Sunday that while there still remained a low chance a member of the general public would be impacted by the disease, officials should still be testing as many people as possible.

    “I think that probably the incidence of this infection in the broader community is still very low,” he said. “But if we want to contain this, if we want to prevent this from becoming an endemic virus, we need to be looking more widely for it. And the worst-case scenario is that we start testing more broadly and we don’t find it. And that would be reassuring. But we should be doing that.”

    more...

    “I think there’s a potential to get this back in the box, but it’s going to be very difficult," Scott Gottlieb said Sunday.

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  • sharon sanders
    replied

    Monkeypox at a daycare was ‘only a matter of time,’ expert says. Next up: pools, sports, schools

    BY ERIN PRATER
    August 7, 2022 at 3:32 PM EDT

    “It was only a mater of time” before monkeypox made it to congregate settings, a pediatric infectious disease specialist told Fortune, after Illinois state officials announced Friday that a daycare worker had been diagnosed with the smallpox-related virus.

    “There is definitely potential for spread of monkeypox” in daycares, schools, college campuses, prisons, and other similar settings, said Dr. Alexandra Brugler Yonts, an infectious disease specialist at Children’s National Hospital in Washington, D.C. She assisted in the FDA’s review of Jynneos—one of two smallpox vaccines licensed for treatment of monkeypox, and the safer of the two by far.

    “Anywhere that close physical, skin-to-skin contact occurs—particularly of people who are in various stages of undress—there is risk,” she said.

    more..

    "With school starting soon, I think this is going to be more widespread," a pediatric infectious disease specialist who worked on the FDA's review of a vaccine for monkeypox told Fortune.

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  • sharon sanders
    replied
    The US has ordered 3 million doses link of the Jyanneous smallpox vaccine so it is important to learn about it.

    Again - FluTrackers does not endorse or promote any product, medicine, vaccine, therapy, treatment, etc.

    If you have any medical questions please contact your medical provider.





    hat tip Lance


    ACAM2000 and JYNNEOS comparison

    CDC presentation slides at ACIP meeting June 2022

    https://www.cdc.gov/vaccines/acip/me...tersen-508.pdf

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  • Pathfinder
    replied
    Can Monkeypox Spread Through Objects like Doorknobs? An Expert Explains as U.S. Cases Surpass 6,500
    ...
    by Vanessa Etienne Updated on August 5, 2022 12:27 PM
    ...
    The virus spreads through skin-to-skin contact. While that may sound similar to COVID-19, Dr. Linda Yancey, infectious disease specialist at the Memorial Hermann Health System in Houston, tells PEOPLE that "this is not a respiratory virus. It is not like COVID, which spreads primarily through the air."

    "Monkeypox is transmitted by skin to skin contact. And that can be any kind of skin to skin contact. I know a lot of the cases here have been transmitted through sex, but it's not a sexually transmitted disease," she explains. "Basically, sex involves a lot of skin to skin contact but so does dancing, so does kissing, so does shaking hands, or doing things like wrestling or football. So there's a bunch of different ways that can be transmitted. Any skin to skin contact is a big risk."
    ...
    According to Yancey, it is "absolutely a possibility" for monkeypox to be transmitted through items like money as the virus can survive for days in an environment.

    "So, monkeypox is a sibling of smallpox. Remember that old story of the U.S. military giving smallpox-infected blankets to Native Americans? This could absolutely be transmitted in that fashion," Yancey says. "And in fact, one of the cases in the U.S. was a lady who was exposed to bed linens. She cleans Airbnbs for a living. So any high touch items like money, doorknobs, shopping carts, have the potential for transmission.
    ...
    "I am a bit concerned because the kids are about to head back to school. You know, this would go through say a wrestling team like wildfire," Yancey tells PEOPLE. "So everybody needs to be warning their kids. Wash your hands. Use hand sanitizer. Just something parents should be aware of."
    ...

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  • sharon sanders
    replied
    Woman with monkeypox. Not only transmitted sexually.

    ----------------------------------------------


    snip

    Seaton is a cashier and believes she likely caught monkeypox at work.

    “I just want y’all to know that I did not do anything sexual to contract this disease. This thing is spreading. It’s here,” Seaton said.



    https://news.yahoo.com/thing-spreadi...st_sjwumo1bpf4

    -------------------------------------------------



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  • sharon sanders
    replied
    This tells you what you need to know about how monkeypox is spread.


    CDC - Monkeypox: Disinfecting Home and Other Non-Healthcare Settings (West African clade only) - July 18, 2022

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  • sharon sanders
    replied
    U.S. officials declare monkeypox a public health emergency - August 4, 2022

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  • Emily
    replied
    Sure, everyone is healthy until they get meningococcal encephalitis.

    [QUOTE=sharon sanders;n955682]
    Helen Branswell
    @HelenBranswell
    I should clarify this. The two men both died from encephalitis triggered by #monkeypox. I don’t *think* pre-existing conditions would have made them more likely to develop encephalitis. The surprise for me was deaths in previously health individuals.
    Quote Tweet



    https://twitter.com/Bakaburg1/status...42663803953154
    Spain Health Ministry announced that both monkeypox deaths were due to encephalitis, an inflammation of the brain due to the infection. The deceaseds were 31 and 40 years of old.




    Angelo D'Ambrosio @Bakaburg1
    MD, Public Health Specialist, ARHAI Expert at
    @ECDC_EU

    Replying to@Monkeypoxtally

    I’m reading it was meningococcal encephalitis.

    4:53 AM · Aug 1, 2022

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  • Pathfinder
    replied
    Translation Google

    Monkeypox: four questions about recent deaths in Brazil, Spain, India and Peru

    The deaths have been chained in recent days, bringing to ten the number of deaths of people carrying monkeypox in the world since May. But the authorities continue to wonder about the real causes of these deaths.

    franceinfo with AFP
    Published on 02/08/2022 14:38
    Updateon 02/08/2022 14:58

    Five people died within a few days. After Spain, which confirmed the death of two patients with monkeypox this weekend, India and Peru announced on Monday August 1 the death of a person carrying the virus in their country. Thursday, Brazil had launched the alert, announcing the first death of a person with the disease, outside the African continent.

    These deaths come in a context where the virus, whose strain originated in West Africa , is spreading around the world. The World Health Organization (WHO) triggered its highest level of alert, the Public Health Emergency of International Concern (USPPI), on July 24 to step up the fight against monkeypox. Franceinfo returns in four questions on these recent deaths of patients with the virus.

    1 Where have the recent deaths been announced?

    The five deaths in recent days are the first deaths of monkeypox patients outside Africa, AFP reports. A total of ten deaths have been recorded worldwide since May, with the first five reported on the African continent, where the disease is endemic and was first detected in humans in 1970.

    The first death outside Africa was recorded in Brazil on July 28 . He is a 41-year-old man who died in Belo Horizonte, in the southeast of the country. According to the country's Ministry of Health, Brazil has so far recorded nearly 1,000 cases of monkeypox, most of them in the states of Sao Paulo and Rio de Janeiro, located in the same region. The first case was detected on June 10, in a man who had traveled to Europe.

    Spain recorded the second death of a monkeypox patient on Saturday. He is a 31-year-old man who was hospitalized at the Queen Sophia Hospital in Cordoba, in the south of the country, according to a press release from the Andalusian authorities. The day before, the country had announced the first death of a patient with this disease ever recorded in Europe.

    With nearly 4,300 people infected as of July 29, according to figures provided by the Spanish Ministry of Health (in Spanish) , Spain is the European country with the highest number of recorded cases of monkeypox. In the country, 120 people affected by the virus have been hospitalized.

    A 22-year-old man also died on Saturday July 30 in India, a week after being hospitalized on his return from the United Arab Emirates, according to Indian authorities. Tests carried out on the 22-year-old victim showed that he had monkey pox. India has recorded at least four cases of the disease, the first of which was on July 15 in another man who returned to Kerala after a trip to the United Arab Emirates.

    In Peru, an HIV-positive patient who had abandoned his HIV treatment and was infected with monkeypox also died on Monday. The 45-year-old man "arrived at the hospital in a very serious condition with monkeypox. His health had deteriorated after he abandoned his treatment for HIV" , said the director of the Dos de Mayo National Hospital, Eduardo Farfan on local radio. Over 300 cases of monkeypox have been recorded in the country.

    2 Has the link between monkeypox and the death of patients been established?

    For the two patients who died in Spain, this is not yet the case. Referring to "two young men" , the Spanish Ministry of Health did not provide further details on the profile of these patients. He referred to "analyzes that may take place later to be able to determine the cause of death" .

    For the 41-year-old patient who died in Brazil, monkeypox should not be the only factor to consider, authorities say. He "was being followed in hospital for other serious clinical conditions" , said the authorities of the state of Minas Gerais, located in the south-east of the country. “It is important to emphasize that he had serious comorbidities, so as not to cause panic in the population ,” also declared the Secretary of Health of Minas Gerais, adding that the patient was undergoing treatment against cancer.

    Further tests are also to be carried out on the man who died in India. The death of the Peruvian patient would have been caused by a weakened immune system according to medical teams. "He did not die of monkeypox but of sepsis ," said the director of the Dos de Mayo national hospital in Lima.

    3 What are the mortality risks from monkeypox?

    According to Imad Kansau , doctor specializing in infectious diseases at Antoine-Béclère hospital in Clamart (Hauts-de-Seine) interviewed by franceinfo, these deaths among people carrying the virus are rare . "These are the complications that occur in immunocompromised patients, therefore patients who are at the stage of diseases that give immunosuppression, that is to say a significant drop in defenses. These patients can die from neurological complications or breathing,” he explains.

    In African countries where the disease is endemic, the mortality rate varies from 1 to 10%, according to the WHO. But, "with proper care, most patients recover," the organization said. In her frequently asked questions , she recalls that "in most cases, the symptoms of monkeypox disappear spontaneously after a few weeks" .

    The European Center for Disease Prevention and Control specifies that the viral strain detected in Europe, originating from West Africa, has an average fatality rate of 3.6% , according to studies carried out in African countries. Severe cases usually occur in newborns, children, and people with immune deficiencies. Among the possible complications, the WHO cites superinfections of the skin, pneumonia or even eye problems.

    “We do not know to what extent this rate is transposable to us: we generally have relatively little information on the characteristics of infected patients in epidemics in Africa and our health systems are very different from those of the countries concerned” , commented for franceinfo the infectiologist Paul Loubet.

    4 Why does WHO Europe foresee an increase in the number of deaths linked to the epidemic?

    Despite this low fatality rate, health authorities are already expecting new deaths, "given the continued spread (of the virus)" , justified in a press release Catherine Smallwood, a situation manager. emergency of WHO Europe.

    "The reporting of monkeypox-related deaths does not change our assessment of the epidemic in Europe. We know that, although self-limiting in most cases, monkeypox can lead to serious complications" , a- she noted, recalling the objective "to quickly interrupt the transmission of the virus in Europe" .

    More than 18,000 cases have been detected worldwide outside of Africa since early May, the majority of them in Europe. In detail, the disease has been reported in 78 countries and 70% of cases are concentrated in Europe, WHO director Tedros Adhanom Ghebreyesus said on Wednesday.


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  • sharon sanders
    replied

    Helen Branswell
    @HelenBranswell
    I should clarify this. The two men both died from encephalitis triggered by #monkeypox. I don’t *think* pre-existing conditions would have made them more likely to develop encephalitis. The surprise for me was deaths in previously health individuals.
    Quote Tweet

    Helen Branswell
    @HelenBranswell
    · 4h
    Unexpected info on Spain's 2 fatal #MPX cases: Both men, aged 31 & 44. No epi link between the cases. Neither was immunocompromised. Neither had underlying chronic diseases. From a presentation by Isabel Jado, director of the National Center for Virology to a @WHO meeting.

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  • sharon sanders
    replied

    CDC documenting a Monkeypox reinfection, plus slides & transcript from a COCA call in June 2022

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