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German patient vaccinated against Covid 217 times
23 hours ago
By Michelle Roberts,Digital health editor
A 62-year-old man from Germany has, against medical advice, been vaccinated 217 times against Covid, doctors report. The bizarre case is documented in The Lancet Infectious Diseases journal. The shots were bought and given privately within the space of 29 months. The man appears to have suffered no ill effects, researchers from the University of Erlangen-Nuremberg say.
'Very interested'
"We learned about his case via newspaper articles," Dr Kilian Schober, from the university's microbiology department, said. "We then contacted him and invited him to undergo various tests in Erlangen. He was very interested in doing so." The man provided fresh blood and saliva samples. The researchers also tested some frozen blood samples of his that had been stored in recent years.
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CORRESPONDENCE|ONLINE FIRST
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual
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In summary, our case report shows that SARS-CoV-2 hypervaccination did not lead to adverse events and increased the quantity of spike-specific antibodies and T cells without having a strong positive or negative effect on the intrinsic quality of adaptive immune responses. While we found no signs of SARS-CoV-2 breakthrough infections in HIM to date, it cannot be clarified whether this is causally related to the hypervaccination regimen. Importantly, we do not endorse hypervaccination as a strategy to enhance adaptive immunity.
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23 hours ago
By Michelle Roberts,Digital health editor
A 62-year-old man from Germany has, against medical advice, been vaccinated 217 times against Covid, doctors report. The bizarre case is documented in The Lancet Infectious Diseases journal. The shots were bought and given privately within the space of 29 months. The man appears to have suffered no ill effects, researchers from the University of Erlangen-Nuremberg say.
'Very interested'
"We learned about his case via newspaper articles," Dr Kilian Schober, from the university's microbiology department, said. "We then contacted him and invited him to undergo various tests in Erlangen. He was very interested in doing so." The man provided fresh blood and saliva samples. The researchers also tested some frozen blood samples of his that had been stored in recent years.
...
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CORRESPONDENCE|ONLINE FIRST
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual
- Katharina Kocher †
- Carolin Moosmann †
- Felix Drost
- Christine Schülein
- Pascal Irrgang
- Philipp Steininger
- et al.
- Show all authors
- Show footnotes
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In summary, our case report shows that SARS-CoV-2 hypervaccination did not lead to adverse events and increased the quantity of spike-specific antibodies and T cells without having a strong positive or negative effect on the intrinsic quality of adaptive immune responses. While we found no signs of SARS-CoV-2 breakthrough infections in HIM to date, it cannot be clarified whether this is causally related to the hypervaccination regimen. Importantly, we do not endorse hypervaccination as a strategy to enhance adaptive immunity.
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