China: 2019nCov - Cases, Outbreak News and Information Week 6 (February 2 - February 8, 2020)

[Treyfish]

Cruise ship under quarantine in Hong Kong, tests for coronavirus conducted as 30 crew members have fever

5 Feb, 2020 05:28 / Updated 9 hours ago
Hong Kong health officials were scrambled to screen crew members aboard a large cruise ship arriving from Taiwan after dozens showed symptoms similar to the deadly coronavirus.

Hong Kong’s health department said that 30 crew members of the World Dream cruise liner, which carried 1,800 people, have symptoms of coronavirus, including fever. Everyone on board is currently being tested for the disease...pics...https://www.rt.com/news/480097-hong-...onavirus-ship/

[Shiloh]

China Is About to Find Out Whether Its Mass Quarantine Worked
“This is more and more like flu, which is like trying to stop the wind.”
By Drew Armstrong
February 4, 2020, 1:10 PM EST

In the last two weeks, China locked down some 50 million people in more than a dozen cities to try and stop the new coronavirus that has sickened thousands in the province of Hubei...

Read more: https://www.bloomberg.com/news/artic...halt-the-virus

[Treyfish]

Mainland Study: Severe or severe cytokine storm in the middle ages, strong immune system response, severe inflammation, injury to itself

2020/2/5
[Ming Pao News] New Coronavirus outbreak in the Mainland, the proportion of elderly patients aged 60 or above is high, and the situation is also seen in Hong Kong. Local cases account for 70%, but the first local deceased was 39 years old and had Diabetic strong man.Mainland researchers suspect that severe pneumonia patients in Wuhan are related to Cytokine storm, which is common in middle-aged adults. Senior physicians with experience in treating SARS patients in 2003 also believe that the cause of death of the dead in Hong Kong is indirectly related to cytokine storms, and cytokines Storms are common in SARS in severely ill patients aged 30 to 50 years...

..The new coronavirus that causes Wuhan pneumonia is suspected to cause cytokine storms in young patients and worsen the condition, as do SARS. Senior physicians who have dealt with SARS patients point out that two or three days after the cytokine storm occurs, some patients will develop acute respiratory distress syndrome, which makes it difficult for patients to breathe, and their condition will rapidly deteriorate and they must go to the intensive care department...
Early Wuhan patients nearly 25 to 49 years old

Researchers analyzed that nearly half of the 41 patients over 65 years of age were severely ill, but especially not that the older the age, the higher the rate of severe illness, 20 of these patients (nearly half) were 25 to 49 years old, More than one-third of them require intensive treatment, a significantly higher proportion than patients between 50 and 64 years of age...https://m.mingpao.com/pns/%e8%a6%81%...87%aa%e8%ba%ab

[Pathfinder]

Translation Google

France in China Consulate General of France in Shanghai

Home > Shanghai > Coming or living in Shanghai > Health > District of Shanghai: local measures taken by the (...)

Shanghai Constituency: Local Actions Taken by Chinese Authorities Relating to nCov Coronavirus


Information on local measures taken by the Chinese authorities relating to the nCov coronavirus

The resumption of work after the New Year holidays is postponed to February 9 at 24 hours in Shanghai and in the provinces of Zhejiang (February 17 in Wenzhou) and Jiangsu. School holidays are extended until the end of February in Shanghai and Wenzhou.
Across the constituency, cultural, tourist and major entertainment venues are closed.
All people who have stayed in areas severely affected by the new coronavirus must spontaneously report to their hotel or their residence.
Many train lines connecting different towns in the district have been suspended. Road connections by bus and inter-provincial bus are suspended.


SHANGHAI


On February 1, the municipality activated a service dedicated to foreigners from its hotline 12345, available from 8h to 20h.

In addition, the office of foreign affairs of the municipality of Shanghai publishes information in several languages including French, follow this link .

Announcements relating to the measures taken by the municipality of Shanghai in the fight against the coronavirus (January 24, 2020)
[…]

All districts set up epidemic monitoring centers, and ensure that containment measures in Shanghai of all persons coming from "severely affected regions", at their homes or in observation establishments be respected. The administrations see to the cancellation of group events, to encourage people to avoid public places, to disinfect and ventilate public places.

[The 14-day confinement can be done at home or in an observation establishment, it consists of two medical visits per day, accompanied by advice on disinfection and personal prevention measures ( municipal health office )]

[...]

Companies are called upon to disseminate prevention messages, to supervise the confinement of their employees returning from severely affected regions, to report all suspicious cases to the authorities, and to take all preventive measures.
Same obligations for officials of administrations, construction sites, places welcoming the public, etc.

[...]

Individuals must cooperate with the authorities, those returning from "severely affected areas" must spontaneously report to the authorities and go into containment, either at home or in medical observation facilities. Those who show symptoms or are ill should follow medical protocols for CPM. Those who do not cooperate will be treated in accordance with the law.

All persons entering Shanghai must complete a medical questionnaire, online or on paper at the points of arrival.

The municipality advises people arriving from other Chinese provinces to stay at home for 14 days.

School holidays are extended until the end of February in Shanghai. The reopening date has not yet been set by the authorities. These measures also apply to the Lyc?e fran?ais de Shanghai, which has set up distance education.

The municipality asks businesses not to resume work before February 9 at midnight.

Administrations, companies, social organizations, and those responsible for public places must ensure that the temperature of people entering these places (including people on duty) is controlled and ask them to wear a mask.

The general population of the city is asked to avoid gathering places and parks (many of which are closed).

Interprovincial bus or coach connections to and from Shanghai are interrupted.

Passenger controls of all vehicles are installed on the main roads around Shanghai (G2, G15, G60, G15, S36, G50, S26, S32, G40).

Regarding the purchase of masks in Shanghai, the municipality announced on January 31 the establishment of a registration system for the purchase of masks in each residence. As of February 1, the residences have informed each household of the system, registrations are open since February 2 and from February 3 the residences inform households of the time at which to buy the masks at the pharmacy to avoid queues. 'expectation and contagions. Each household can buy 5 masks per distribution.

It is compulsory to wear a mask in the Shanghai metro, upon entering the stations. Temperature controls are gradually being implemented in a number of metro stations (including Pudong and Hongqiao airports, Hongqiao station, South station, and Shanghai station).

ZHEJIANG


The province is asking businesses not to resume work before February 9 at midnight (February 17 in Wenzhou).
School holidays extended until February 17 throughout the province, from elementary school to university.

Vehicle controls are implemented in the main roadways (motorways) for passenger examination.

HANGZHOU

The municipality implemented strict confinement at the level of residences / districts and villages on February 4, 2020. Temperature and identity controls are implemented. People who have transited or stayed in areas severely affected by the epidemic must register within one hour of their arrival. The municipality invites residents to go out as a minimum, and to designate one person per household to go out every other day to refuel.

WENZHOU

From February 1 to 8, strict confinement is imposed on all households, one person per household can register to go out every two days to go shopping.

The resumption of work is postponed to February 17 for companies in the city of Wenzhou . Schools (from kindergarten to higher) will welcome students on March 1st.

All bus lines are stopped, as well as the inter-provincial lines and some lines connecting cities and counties. The railway line S1 is suspended. All public activities are canceled and collective gatherings suspended (exhibitions, markets, services, etc.), the majority of public places have been closed.

JIANGSU


School holidays extended until February 17 in Nanjing, Suzhou and Wuxi.

Local authorities are asking businesses across the province not to resume work until 9:00 a.m. on February 9 (except utilities, supplies and involved in the fight against the epidemic.

Passenger controls of all vehicles are installed on the main roads around Zhenjiang, Wuxi, Suzhou, Yangzhou, Changzhou.

People who have stayed in severely affected areas should report to their hotel or residence.

NANKEEN

The wearing of the mask is compulsory in all public places in Nanjing including restaurants, cinemas, shopping centers.

ANHUI


People who have stayed in severely affected areas should report to their hotel or residence.

Controls of all vehicles are set up on the main highways including highways. Inter-provincial road (bus, coach) connections and certain inter-city (bus, coach) connections are suspended.

The school holidays are extended, the dates of resumption will be announced later. Follow the news


The provinces of Anhui, Jiangsu and Zhejiang as well as the municipality of Shanghai inform the population through their wechat public accounts (in Chinese, possibility of translation with the Wechat translation tool or other software on phones) :

Names of wechat public accounts:

SHANGHAI: shanghaifabu

JIANGSU: jstvjsxw

ANHUI: anhuifabu

ZHEJIANG: zjfabu



Last modified: 02/05/2020

https://cn.ambafrance.org/Circonscri...prises-par-les

[Pathfinder]

Translation Google

Interpretation of pneumonia diagnosis and treatment plan for new coronavirus infection (trial version 5)

Published: 2020-02-05Source : Medical Administration and Hospital Authority
　　On February 5, 2020, the National Health and Health Commission issued the "Diagnosis and Treatment Plan for New Coronavirus Infected Pneumonia (Trial Fifth Edition)" (hereinafter referred to as the "Fifth Edition of the Diagnosis and Treatment Plan"). The main contents are now read as follows.
　　December 2019 Since then, Wuhan City, Hubei Province has successively found multiple cases of patients with pneumonitis infected by a new type of coronavirus. With the spread of the epidemic, other cases have been found in other regions of China and abroad. Most of the currently reported cases have a history of Wuhan residence or travel In some areas, no cases of travel history in Wuhan have been found. The disease has been included in the Class B infectious diseases stipulated in the Law of the People's Republic of China on the Prevention and Control of Infectious Diseases, and measures for the prevention and control of Class A infectious diseases have been taken. After the
　　outbreak, Relevant experts organized by the National Health and Health Committee have formulated the trial, trial second edition, trial third edition, and trial fourth edition of the New Coronavirus Infected Pneumonia Diagnosis and Treatment Plan. The
　　fifth edition of the trial includes the pathogenic and clinical characteristics of coronavirus . , Case definition, differential diagnosis, case discovery and reporting, treatment, release and isolation criteria, referral The principles of transport and hospital infection control.
　　First, the pathogenic characteristics of the coronavirus introduced the subfamily of coronavirus into four genera: α, β, γ, and δ. In addition to the newly discovered coronavirus, it is known to infect people. There are 7 types of coronaviruses. Most coronaviruses cause upper respiratory tract infections, and the Middle East respiratory syndrome-associated coronavirus, severe acute respiratory syndrome-associated coronavirus, and this new type of coronavirus can cause pneumonia, even severe pneumonia, and can It is transmitted from person to person.
　　Coronavirus is sensitive to ultraviolet rays and heat. Most disinfectants can effectively inactivate the virus, but chlorhexidine cannot effectively inactivate the virus. Hand disinfectants containing chlorhexidine should be avoided.
　　Second, epidemics The source of infection was changed to "The source of infection currently seen is mainly patients with new coronavirus infection. Asymptomatic infection may also become the source of infection."
　　Third, clinical manifestations. The incubation period is 1-14 days, usually 3-7 days. Main symptoms are fever, fatigue, and dry cough. A few patients have symptoms such as nasal congestion, runny nose, and diarrhea. Because some severely ill patients had no obvious dyspnea and manifested as hypoxemia, it changed to "Severely ill patients often have dyspnea and / or hypoxemia one week after the onset of illness, and the severe cases progress rapidly to acute respiratory distress syndrome, sepsis Symptomatic shock, difficult to correct metabolic acidosis, and coagulation dysfunction, etc. "emphasized that" light patients only showed low fever, mild fatigue, etc., and no pneumonia. "
　　Laboratory tests increased" Some patients may appear liver enzymes, LDH, Myoenzyme and myoglobin increased; troponin increased in some critically ill patients. "And" New coronavirus nucleic acids can be detected in nasopharyngeal swabs, sputum, lower respiratory secretions, blood, feces and other specimens. "
　　Chest imaging Multiple small patchy shadows and interstitial changes appeared early, and the extrapulmonary bands were obvious. Furthermore, it develops multiple ground glass infiltration and infiltrates in both lungs. In severe cases, pulmonary consolidation and pleural effusion are rare.
　　Fourth, case diagnosis is treated differently between Hubei Province and other provinces outside Hubei Province.
　　Other provinces outside Hubei are still divided into "suspected cases" and "confirmed cases". Based on confirmed cases that have been found to have no clear epidemiological history, "those with no clear epidemiological history are in line with 3 clinical manifestations (fever and / or respiratory symptoms; with the above-mentioned characteristics of pneumonia imaging; total white blood cells in the early stages of onset) Normal or decreased, or lymphocyte count decreased.) "Suspected cases were also included for investigation. The diagnostic criteria for confirmed cases have not changed (requires real-time fluorescent RT-PCR for respiratory or blood specimens to detect positive new-type coronavirus nucleic acid; or viral gene sequencing, which is highly homologous with known new coronaviruses.)
　　Hubei Province added "clinical diagnosis "classification. And the "suspected case" standard is modified to: whether with or without epidemiological history, as long as it meets the two clinical manifestations of "fever and / or respiratory symptoms" and "normal or reduced white blood cells in the early stage of onset, or decreased lymphocyte count", then Can be considered a suspected case. This is equivalent to the relaxation of suspected cases. Suspected cases with pneumonia imaging features are clinically diagnosed cases. The diagnostic criteria for confirmed cases have not changed.
　　Fifth, clinical typing. According to whether there are clinical symptoms, whether there is pneumonia, the severity of pneumonia, whether there is respiratory failure, shock, whether there is other organ failure, etc., it is divided into mild (clinical symptoms, no pneumonia on radiology); ordinary (fever, Respiratory symptoms such as pneumonia on imaging studies); severe (respiratory distress, RR≥30 beats / min; resting state, oxygen saturation ≤93%; arterial blood oxygen pressure (PaO ₂ ) / oxygen concentration ( FiO ₂ ) ≤ 300mmHg) and critically severe (respiratory failure occurs and requires mechanical ventilation; shock occurs; combined with other organ failure requires ICU monitoring and treatment.)
　　Sixth, differential diagnosis. There are more than 100 species of pathogens that cause community-acquired pneumonia, of which viruses account for about 30%, and pneumonia caused by other viruses and common influenza viruses, parainfluenza viruses, adenoviruses, respiratory syncytial virus, rhinoviruses, human metapneumoviruses Viruses, SARS coronaviruses, etc. have similarities. It is difficult to distinguish from clinical manifestations and chest imaging alone, and they need to be distinguished by pathogenic testing.
　　Seventh, case detection, reporting and exclusion. Hubei Province is different from other provinces outside Hubei.
　　In other provinces outside Hubei, the case detection was the same as the defendant's procedure and the fourth edition. There was no change in the case. It was stressed that the transfer should ensure that the suspected patient was transferred to the designated hospital as soon as possible under the premise of ensuring the safety of the transfer.
　　For Hubei Province, medical staff at all levels and types of medical institutions are required to immediately isolate and treat suspected and clinically diagnosed cases that meet the definition of the case. Suspected and clinically diagnosed cases should be isolated in a single room. Suspected and clinically diagnosed cases should be isolated. Specimens should be collected for pathogenic testing as soon as possible.
　　Suspected cases should be tested negative for two consecutive consecutive respiratory pathogenic nucleic acid tests (sampling interval of at least 1 day).
　　Eighth, treatment includes isolation, symptomatic support, and close monitoring of changes in the condition, especially respiratory rate, finger saturation, etc.
Suspected cases should be treated in isolation in a single room, and confirmed cases can be admitted to the same ward.
　　Critical cases should be admitted to ICU as soon as possible.
　　Antibacterial use: Avoid blind or inappropriate use of antibacterials, especially the combination of broad-spectrum antibacterials.
　　Antiviral treatment: Add "No effective antiviral treatment is currently confirmed." On the basis of alpha-interferon nebulization inhalation, lopinavir / ritonavir may be added, "or ribavirin may be added ". At the same time, pay attention to adverse reactions related to lopinavir / ritonavir, diarrhea, nausea, vomiting, liver damage, and interaction with other drugs.
　　Successful treatment of severe and critical cases is the key to reducing mortality. It is necessary to actively prevent complications, treat underlying diseases, prevent secondary infections, and provide organ function support in a timely manner. Patients often have anxiety and fear, and psychological counseling should be strengthened.
Condition monitoring, adding "conditionally feasible cytokine testing."
　　Respiratory support: (1) Oxygen therapy: Severe patients should receive nasal cannula or mask to inhale oxygen, and timely evaluate whether respiratory distress and / or hypoxemia is relieved . (2) High-flow nasal catheter oxygen therapy or non-invasive mechanical ventilation: When patients with respiratory distress and / or hypoxemia cannot be relieved after receiving standard oxygen therapy, high-flow nasal catheter oxygen therapy or non-invasive ventilation can be considered. Emphasis "if the condition does not improve or worsen within a short period of time (1-2 hours), tracheal intubation and invasive mechanical ventilation should be performed in a timely manner." (3) Invasive mechanical ventilation: lung protective ventilation strategy, that is, small tidal volume ( 4-8ml / kg ideal body weight) and low inspiratory pressure (platform pressure <30cmH ₂ O) for mechanical ventilation to reduce ventilator-related lung injury. (4) Salvage treatment: For patients with severe ARDS, it is recommended to perform lung expansion. In the case of sufficient human resources, prone ventilation should be performed for more than 12 hours per day. If the prone position does not respond well, ECMO should be considered as soon as possible if conditions permit.
　　Circulation support: Based on adequate fluid resuscitation, improve microcirculation, use vasoactive drugs, and perform hemodynamic monitoring if necessary.
　　Other treatment measures: According to the patient's dyspnea and chest imaging progress, glucocorticoids can be used within a short period (3 to 5 days) as appropriate. The recommended dose does not exceed 1 to 2 mg / kg / day of methylprednisolone. It should be noted that Large doses of glucocorticoids will delay the removal of coronavirus due to immunosuppressive effects; Xuebijing 100ml / time can be administered intravenously, twice daily treatment; intestinal microecological regulators can be used to maintain intestinal microecological balance , To prevent secondary bacterial infections; plasma treatment can be used in recovery period; for critically ill patients with high inflammatory response, conditions can consider using extracorporeal blood purification technology.
　　About Chinese medicine treatment. The disease belongs to the category of traditional Chinese medicine epidemic. The disease is caused by the epidemic qi, and the disease is located in the lungs. The basic pathogenesis is "wet, hot, poisonous, and stasis." Refer to the recommended scheme for dialectical treatment.
　　Ninth, lift the isolation and discharge standards. On the basis of "the body temperature returned to normal for more than 3 days and the respiratory symptoms improved significantly", the "pulmonary imaging showed obvious absorption of inflammation" was added, and the nucleic acid test for respiratory pathogens was negative for two consecutive times (sampling interval at least 1 day), which could be released from isolation and discharged. Or transfer to the appropriate department according to the condition to treat other diseases.
　　Tenth, the principle of transshipment. In order to ensure the safety of transport, patients should be transported in special vehicles, and personal protection and vehicle disinfection of transport personnel should be done.


 

 

　　Related Links: Notice on Printing and Distributing Pneumonia Diagnosis and Treatment Plan for New Coronavirus Infection (Trial Version 5)

http://www.nhc.gov.cn/yzygj/s7652m/2...e4db22ea.shtml

[Pathfinder]

New crown virus is very cunning. Some studies say that the virus first attacks the deep alveoli of the human body.

February 01, 2020 10:31 source: China News Network to Engage in interactionparticipate in the interaction

　　China News Online February 1st (Reporter Chen Jing) Why is the new crown virus so cunning? Why do some patients quietly infect others without obvious symptoms? There are some answers to the questions that exist in people's minds. Professor Zuo Wei of Tongji University School of Medicine and Dongfang Hospital affiliated to Tongji University told reporters on the 1st that the virus does not attack the upper respiratory tract first, but the alveoli located deep in the human body.

　　On the left, the team's latest research results show that type II alveoli or target cells infected with 2019-nCoV. The team published the research results on the preprinted website bioRxiv, with a view to making it visible to their colleagues as soon as possible.

　　Since the outbreak of the new coronavirus (2019-nCoV) pneumonia, scientists have cooperated in the hope that they can find a therapeutic target in a short period of time and provide the right medicine. Zuo Wei, a dual-employed professor at Tongji University and the affiliated Dongfang Hospital, conducted in-depth analysis of the mechanism and pathway of human infection with the new coronavirus. The left is: "Where does the receptor door open, and which part of the virus will it attack first? We all want to know."

　　In an interview, said that the left is the introduction. The team analyzed the single-cell RNA sequencing data of more than 43,000 human lung cells (healthy people) for the patients in the library by using a shared database and high-throughput single-cell sequencing method. Find where the virus first attacked.

　　Zuo's team also explained the mechanism of Wuhan coronavirus infecting human lung epithelial cells. It is reported that there is a significant difference between the new crown virus and SARS that year. Many of the detected patients have no obvious symptoms. Individuals do not even cough or fever, but the lung CT has lesions; others have no symptoms but But it infected others.

　　In this regard, Zuo Wei pointed out that the virus enters the human body, directly into the alveoli, and quickly activates the body's inflammatory response to attack lung tissue. The expert also said that there is no nerve tissue in the alveoli, so the patient does not cough very much. Zuo Wei pointed out that the type of inflammatory response activated by this virus may be different from the common type of inflammatory response, so some patients' fever is not obvious. The scholar admits that deeper reasons need to be further studied

　　Zuo Wei told reporters that the team's research is still ongoing. I believe that with the increase in sample size and further research, more valuable conclusions will come out soon. He called on the teams to work together to analyze the lung structure of patients as soon as possible. "Only as early as possible to analyze the pathological anatomy, can we truly understand the mechanism of infection and inflammation, so as to carry out targeted prevention and control," Zuo emphasized.

[Edit: Ji Xiang]

http://www.chinanews.com/sh/2020/02-01/9074881.shtml

[Treyfish]

The head of the U.S. Travel Association says travel to and from China should continue during the outbreak of the coronavirus despite current fears and the pleas of Chinese travel companies for visitors to stay home.

Roger Dow, president and CEO of the U.S. Travel Association, prefaced his state of the travel industry address Wednesday with an update on the virus and said, “while visitation from China will be temporarily affected, all of the current expert advice indicates that business and leisure travel in the U.S. can and should continue as normal.”

That suggestion contrasts with the advice of a leading Chinese travel company whttps://www.reviewjournal.com/busine...china-1951318/

[Pathfinder]

Translation Google

Wuhan pneumonia / 32-year-old patient "tested 5 times" before confirming doctor's approval of virus is too cunning

February 05, 2020 Editing / Gan Zhonghao

The outbreak of pneumonia in Wuhan in mainland China is raging, and multiple cases of infection have been confirmed in Zhangzhou, Fujian. Among them, 1 case is very rare, and it is called the Zhangzhou version of "Holmes" -style cracked diagnosis!

According to "Xiamen.com", the 32-year-old patient had a history of living in Wuhan. When he returned to Zhangzhou from Wuhan on January 22, he developed fever, stuffy nose, runny nose, and fatigue. His body temperature was about 38.5 degrees. The antipyretic medicine was invalid, and went to the hospital for treatment on the 29th.

Zhangzhou Hospital believes that because the patient has a history of living in Wuhan, the epidemic prevention team in the hospital immediately let the patient enter the isolation ward for treatment. Although the condition is similar to Wuhan pneumonia, it still needs to be tested positive to be confirmed. I did not expect the first test result to be negative. The attending doctor thought that there was an error and thought it might be the test operation specification was wrong. The test was repeated on the 30th and the result was still negative.

However, according to the diagnosis of the epidemic prevention team, the chest condition of this patient is similar to that of patients with pneumonia in Wuhan. Therefore, the hospital still insisted on continuous inspection and finally tested positive for the new coronavirus at the fifth test on the 2nd. Lin Li, deputy leader of the epidemic prevention team and director of the department of respiratory and intensive medicine, shouted, "The virus is too cunning and hides too deeply."

With the assistance of the epidemic prevention team, the patient has had a high fever, and her cough and chest tightness have improved. Her condition is stable, but further treatment and observation are needed.

https://www.ctwant.com/article/35544

[Hallinen]

In regards to coronavirus resistance to common disinfectants...J Hosp Infect. 1998 Apr;38(4):283-95. The action of three antiseptics/disinfectants against enveloped and non-enveloped viruses.

Wood A¹, Payne D.https://www.ncbi.nlm.nih.gov/pubmed?term=9602977

Chloroxylenol, benzalkonium chloride and cetrimide/chlorhexidine were not effective against coronavirus.

[Pathfinder]

2020-02-05 21:44:16 Beijing News reporter: Lu Tong editor: Zhao Kaidi

Doctors respond to "CT alternative nucleic acid test" remarks: don't miss the wrong time

Beijing News (Reporter Lu Tong) Tonight (February 5), a reporter from the Beijing News learned from Wuhan University Zhongnan Hospital that the "CT Alternative Nucleic Acid Test" released by Zhang Xiaochun, the deputy director of the medical imaging department of the hospital, was released in a circle of friends. Zhang Xiaochun responded to this speech. "The views I shared in my circle of friends a few days ago are based on scientific evidence and clinical experience," she said.

Zhang Xiaochun's previous comments. Network screenshot

"CT Alternative Nucleic Acid Detection" View Draws Attention

In the past few days, a screenshot of the circle of friends of Zhang Xiaochun, the deputy director of the Medical Imaging Department of Central South Hospital, has been circulating on the Internet, causing concern. The screenshot text said, "Don't be superstitious for nucleic acid detection anymore, and CT images are strongly recommended as the main basis for the current 2019-nCoV (new coronavirus) pneumonia."

In addition, the content of the circle of friends also mentioned that at present, families in Wuhan have more and more clustered outbreaks, and most of them are concealed, and even have multiple nucleic acid negatives without any clinical symptoms. If you use home observation methods, the epidemic will inevitably spread further. Should start immediately as long as those who have had contact with the suspected case to check the CT, as long as the CT is positive and concentrated in the hotel or hotel or school, mobilize social forces to participate in the work.

Finally, this circle of friends content proposal: outbreak control is about human life, and people who are asymptomatic or nucleic acid-negative CT-positive can not be allowed to watch the family. Governments at all levels have taken action to prevent families from staying unnoticed and separated from each other. Secondary outbreaks spread.

Response says nucleic acid testing remains gold standard

This afternoon, Zhang Xiaochun made his first public statement on his previous remarks.

"The viral nucleic acid test is the gold standard for the non-invasive diagnosis of new coronavirus pneumonia. However, the results of the test are 'CT-positive and nucleic acid-negative', which may affect clinical investigation. At present, the new-type coronavirus nucleic acid test has high specificity and sensitivity. Low, which does not rule out the existence of some false negatives. "

Zhang Xiaochun believes that shortly after the new coronavirus is discovered, detection and diagnosis require a certain process of recognition. In addition, the short development time of nucleic acid kits, the shortage of existing sampling staff, and the relatively long detection time of nucleic acid reagents, etc. It is difficult for a large number of close contacts, family observations and highly suspected patients to detect and diagnose.


"CT examination is convenient, fast, and intuitive. It is easy to popularize in primary-level hospitals. Although CT is only an auxiliary diagnostic method, in today's severe situation of the new crown virus pneumonia, prevention and control in Wuhan and other regions must take the unconventional method of" don't miss one ". To reduce cross-infection. "

Zhang Xiaochun said in the response that patients who are CT positive and virus nucleic acid negative should also be included in the scope of isolation treatment. In a very period of time, it would be better to avoid mistakes, and even other pathogens pneumonia will benefit from timely treatment. Only in this way can we control the source of infection and cut off the transmission route as soon as possible, so that as many people as possible are not infected, and the infected asymptomatic patients can be detected and treated early.

"Imaging Features" has been written into the new version of the diagnosis and treatment plan

Xu Haibo, director of the Department of Medical Imaging of Zhongnan Hospital of Wuhan University and deputy chairman of the Neurological Committee of the Chinese Society of Radiology, said in the response that CT is both a professional and evidence-based tool; it is also a diagnostician and an evaluator. Therefore, CT has unique advantages as a rapid diagnosis. In areas with severe outbreaks such as Hubei, CT screening may become the preferred method for diagnosing new coronary pneumonia.

In response, Zhang Xiaochun's views were recognized by some domestic experts. According to reports, Prof. Zhao Shihua from Beijing Fuwai Hospital, Prof. Wu Jianlin from Zhongshan Hospital of Dalian Medical University, Prof. Ou Shanxing, Chief Physician of Radiology Department of Southern Military General Hospital of Chinese People's Liberation Army, and many other industry experts have recently used telephone, WeChat or self-media platforms. Contact Zhang Xiaochun to express her approval and support for her opinion.


The reporter noticed that on February 4, the General Office of the National Health Commission and the State Administration of Traditional Chinese Medicine jointly issued the "Pneumonitis Diagnosis and Treatment Program for New Coronavirus Infection (Trial Fifth Edition)". "As the standard for clinical diagnosis of Hubei Province.

Edited by Kaidi Zhao

Proofreading Li Xiangling

http://www.bjnews.com.cn/feature/2020/02/05/685008.html

[Shiloh]

Source: http://china.qianlong.com/2020/0206/3656682.shtml

Respiratory symptoms" included in the criteria for judging suspected cases of new coronavirus
2020-02-06 06:07 Beijing Daily

Original Title: New Coronavirus Infected Pneumonia Fifth Edition Diagnosis and Treatment Plan Announced

"Respiratory symptoms" included in the criteria for suspected cases

Pathways for aerosol and digestive tracts to be identified

Yesterday (5th), at the press conference of the Joint Prevention and Control Mechanism of the State Council, relevant experts interpreted the newly announced "Pneumonitis Diagnosis and Treatment Program for New Coronavirus Infection (Trial Fifth Edition)", and "respiratory symptoms" were included in the criteria for judging suspected cases. The aerosol and digestive tract transmission channels have yet to be clarified.

Does not rule out the possibility of transmission through the digestive tract

Regarding the route of transmission of the virus, the description in the fourth edition of the diagnosis and treatment plan is "transpiration via respiratory droplets is the main route of transmission, and it can also be transmitted through contact." The fifth edition of the diagnosis and treatment plan states that "transmission through respiratory droplets and contact are The main routes of transmission, such as aerosols and digestive tracts, have yet to be identified. "

Guo Yanhong, Supervisor of the Medical Administration and Hospital Administration of the National Health and Health Commission, said that most cases are currently transmitted by the respiratory tract and droplets, but the stool also detected positive nucleic acid tests, so the possibility of transmission through the digestive tract is not ruled out. Sex. The description of the transmission route in the plan is based on the clinical, occurrence, and development characteristics of the disease, and relevant experience is incorporated in time to guide clinical practice.

"In the fourth edition of the diagnosis and treatment plan, fecal examination has been used as one of the specimens for examination." Said Li Xingwang, a member of the National Medical Expert Group and the chief expert of the Infectious Diseases Diagnosis and Research Center of Beijing Ditan Hospital, including nasopharyngeal swabs, sputum, Specimens including lower respiratory tract secretions, blood, and feces can be submitted for inspection, as nucleic acid positives may be found in these specimens.

Li Xingwang said that it is unclear whether the new coronavirus has aerosol transmission, including whether there is an intestinal transmission route after the virus is detected in the stool, and there is no further evidence at present.

Asymptomatic infection may also be a source of infection

The new version of the diagnosis and treatment program changed the source of infection to "the current source of infection is mainly patients with new types of coronavirus infection. Asymptomatic infection may also become the source of infection." The case diagnosis classification has been added with "light", and changed to "light, "Ordinary, heavy and critical" four categories.

"With the improvement of detection ability, we found that pneumonitis infected by the new coronavirus not only showed the symptoms of pneumonia, but some patients showed relatively mild and no pneumonia." Li Xingwang said that these patients had fever, moderate to low fever, mild fatigue, and occasionally She had a dry cough and no pneumonia in her history. Although these patients are mild, they are still contagious. "In diagnostic typing, we added this type to isolate and treat these patients for better control of the source of infection. At the same time, the basic characteristics of patients were also described in more detail."

"Respiratory symptoms" may be listed as suspect

In the fifth edition of the diagnosis and treatment plan, in addition to "fever", the criteria for judging suspected cases were also added "with respiratory symptoms".

"We found that mild patients have low fever or respiratory symptoms, so we corrected the fever symptoms in suspected cases and increased the 'fever or respiratory symptoms'." Li Xingwang revealed that the purpose is also to detect patients early, early diagnosis, early Isolation treatment. "This may lead to an increase in the number of suspected cases in the future." Li Xingwang said, if this part of the less typical cases can be searched out early, it is also very beneficial to control the epidemic and control the source of infection.
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Editor: Zhang Chi (QN0009) Author: Liu Huan

[Shiloh]

Source: http://wjw.hubei.gov.cn/fbjd/dtyw/20..._2019847.shtml

Epidemic situation of new coronavirus infection in Hubei Province on February 5, 2020
2020-02-06 06:07 | Hubei Provincial Health Committee

From 00:00 to 24:00 on February 5, 2020, 2987 new pneumonia cases of new coronavirus infection were added in Hubei Province, of which: 1766 in Wuhan, 424 in Xiaogan, 162 in Huanggang, 128 in Suizhou, and Jingzhou 88 cases, 86 cases in Jingmen City, 67 cases in Yichang City, 57 cases in Huangshi City, 52 cases in Xiangyang City, 41 cases in Ezhou City, 40 cases in Xiantao City, 35 cases in Shiyan City, 15 cases in Xianning City, 10 cases in Tianmen City, Qianjiang City There were 10 cases in the city and 6 cases in Enshi Prefecture. There were 70 new deaths in the province, including 52 in Wuhan, 2 in Yichang, 1 in Jingzhou, 1 in Jingmen, 7 in Xiaogan, 4 in Huanggang, 1 in Xianning, 1 in Suizhou, One case in Xiantao City. A total of 113 new patients were discharged, including 63 in Wuhan, 7 in Huangshi, 5 in Shiyan, 3 in Xiangyang, 9 in Jingzhou, 5 in Jingmen, 2 in Ezhou, 3 in Xiaogan, and Huanggang There were 10 cases, 1 in Xianning City, 4 in Enshi Prefecture, and 1 in Tianmen City.

As of 24:00 on February 5, 2020, 19665 cases of pneumonia of new coronavirus infection have been reported in Hubei Province, including 10117 cases in Wuhan, 1886 cases in Xiaogan City, 1807 cases in Huanggang City, 834 cases in Suizhou City, and 801 cases in Jingzhou City. 787 cases in Xiangyang City, 566 cases in Huangshi City, 563 cases in Yichang City, 508 cases in Jingmen City, 423 cases in Ezhou City, 399 cases in Xianning City, 353 cases in Shiyan City, 265 cases in Xiantao City, 144 cases in Enshi Prefecture, and 138 cases in Tianmen City There were 64 cases in Qianjiang City and 10 cases in Shennongjia Forest District. 633 patients have been cured and discharged. There were 549 deaths, including: 414 in Wuhan, 2 in Huangshi, 2 in Xiangyang, 6 in Yichang, 10 in Jingzhou, 17 in Jingmen, 18 in Ezhou, 25 in Xiaogan, and 29 in Huanggang. 1 in Xianning, 9 in Suizhou, 5 in Xiantao, 10 in Tianmen, and 1 in Qianjiang. At present, 14314 cases are still being treated in the hospital, including 2328 cases of severe cases and 756 cases of critical cases, all of which are receiving isolation treatment at designated medical institutions. A total of 90,997 close contacts have been tracked, and 64,127 people are still under medical observation.

[Treyfish]

27,447 confirmed
23,260 suspected
1109 cured
563 dead

https://news.qq.com//zt2020/page/feiyan.htm

[Shiloh]

Source: http://news.cnwest.com/tianxia/a/202.../18443671.html
Update on pneumonia of new coronavirus infections as of 24:00 on February 5

Time: 2020-02-06 07:38:47 Source: National Health and Medical Commission Website

From February 0 to 2 on February 5, 31 provinces (autonomous regions, municipalities) and the Xinjiang Production and Construction Corps reported 3694 new confirmed cases, 261 new cured cases, and 21,365 close contacts who were released from medical observation on the same day. There were 640 new severe cases, 73 new deaths (70 in Hubei Province, 1 in Tianjin, 1 in Heilongjiang, and 1 in Guizhou), and 5328 new suspected cases.

As of 24:00 on February 5th, 31 provinces (autonomous regions, municipalities) and the Xinjiang Production and Construction Corps had reported a total of 28,018 confirmed cases, a total of 1153 cases were cured and discharged, 26,302 cases were isolated (including 3,859 severe cases), and a total of 563 died Cases, there are 24,702 suspected cases. A total of 282,813 close contacts were traced, and 186,354 close contacts were still in medical observation.

A total of 42 confirmed cases were reported from Hong Kong, Macao and Taiwan: 21 in the Hong Kong Special Administrative Region (1 death), 10 in the Macao Special Administrative Region and 11 in Taiwan.

[Ronan Kelly]

Update on pneumonia of new coronavirus infections as of 24:00 on February 5
Published: 2020-02-06Source : Health Emergency Office
　　From February 0 to 2 on February 5, 31 provinces (autonomous regions, municipalities) and the Xinjiang Production and Construction Corps reported 3694 new confirmed cases, 261 new cured cases, and 21,365 close contacts who were released from medical observation on the same day. There were 640 new severe cases, 73 new deaths (70 in Hubei Province, 1 in Tianjin, 1 in Heilongjiang, and 1 in Guizhou), and 5328 new suspected cases.
　　As of 24:00 on February 5th, 31 provinces (autonomous regions, municipalities) and the Xinjiang Production and Construction Corps had reported a total of 28,018 confirmed cases, a total of 1153 cases were cured and discharged, 26,302 cases were isolated (including 3,859 severe cases), and a total of 563 died Cases, there are 24,702 suspected cases. A total of 282,813 close contacts were traced, and 186,354 close contacts were still in medical observation.
　　A total of 42 confirmed cases were reported from Hong Kong, Macao and Taiwan: 21 in the Hong Kong Special Administrative Region (1 death), 10 in the Macao Special Administrative Region and 11 in Taiwan.
 

 

(Note: When quoted by the media, please mark "Information comes from the official website of the National Health and Health Commission.")

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