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UK: 607 confirmed fatalities due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Source: http://www.telegraph.co.uk/health/h...rges-at-risk-to-get-flu-jab-as-wife-dies.html

Flu outbreak: husband urges at risk to get flu jab as wife dies

A devastated husband has urged people to get vaccinated after his 41-year-old wife was revealed as another victim of swine flu.

Katrina Mullen, of Scarborough, North Yorks., died from the deadly flu strain at Scarborough Hospital at the weekend...

More at link above
 
Re: UK: 112 confirmed fatalities (174 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (174 reported fatalities), 800+ Patients in intensive care due to influenza

Source: http://www.staffordshirenewsletter.co.uk/News/Probe-into-hospital-flu-death.htm

Probe into hospital flu death

HOSPITAL chiefs are awaiting the results of tests that could confirm the first recorded swine-flu death in Stafford this year.

The probe follows the death of a patient, understood to be a man in his 50s, suffering flu-like symptoms at Stafford Hospial on Monday.

More at link above
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Leanne may never know she's a mum


SWINE flu victim Leanne Gunnell lay in a coma last night - a few wards from the baby girl she will probably never know. ...

http://www.thesun.co.uk/sol/homepage/news/3351134/Swine-flu-girl-may-never-know-shes-a-mum.html
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Swine flu advice for Liverpool parents after 11th victim in region named



MERSEYSIDE health chiefs issued advice to parents worried about swine flu last night, as the known death toll reached 11 in the region.

Parents have expressed concern after the death of Birmingham three-year-old Lana Ameen, a perfectly healthy child not eligible for the vaccine.

But health bosses claimed expert advice categorically said only children with health problems should be vaccinated.

It comes as the Daily Post was made aware of an 11th swine flu death in the region.

Eleanor Carruthers, 68, from Wavertree, had been given the flu jab, but still died from the disease.

http://www.liverpooldailypost.co.uk...r-11th-victim-in-region-named-92534-27983470/
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

14 treated for swine flu in Western Trust

Fourteen people are being treated for swine flu by the Western Trust, the Public Health Agency has revealed.

An additional 20 people are waiting to find out of they have the virus.

The PHA also confirmed that 17 people - including two with no underlying health conditions - have died from swine flu in Northern Ireland since November.

Dr Anne Kilgannon from the Western Trust said Altnagelvin was busier than most hospitals over Christmas, but staff were coping well.

"Although the numbers are small we have been busier than in other hospitals in Northern Ireland.

"However I think it's important to say we have coped well.

"We had predetermined plans in place and our staff have implemented those."

http://www.bbc.co.uk/news/uk-northern-ireland-12190187
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza


School pupil, 4, is latest victim of swine flu in acounty



A FOUR-YEAR-OLD child who contracted swine flu in hospital after being admitted with pneumonia is recovering at home.

The youngster, who is a pupil at Werrington Primary School, was taken ill at the beginning of December and spent Christmas in hospital.

Headteacher Nicola Walker sent out a letter to parents earlier this week to scotch rumours a case of swine flu had been reported at the school.

Mrs Walker stated: "On December 9 one of our nursery pupils was admitted to hospital with pneumonia and unfortunately remained in hospital throughout the Christmas period.

"While in hospital the pupil then contracted swine flu. The pupil has recently been discharged from hospital and is now recovering at home.

"I did not feel it was appropriate for me to write to parents as the pupil in question had not been on the school site immediately prior to contracting swine flu or during the period in which they were ill and so posed no risk to the other pupils."

Parent Danielle Edwards, aged 30, of Leek, has just recovered from swine flu.

http://www.thisisstaffordshire.co.u...swine-flu/article-3101370-detail/article.html
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Family?s agony at dad?s suspected swine flu death


A HEALTHY father-ofthree has died of suspected swine flu.

Chef Stephen Hall, aged 45, from Westhoughton, died at the Royal Bolton Hospital on Saturday.

His wife Lynda described him as ?a gentle, kind and caring man? and said she cannot believe what has happened.

Mrs Hall, aged 46, said: ?It?s just so unfair. He was a big, strong, healthy man.

He never smoked and didn?t drink, apart from the odd tipple, he never had any problems. I just keep thinking it?s a dream and I?m going to wake up.?

Mr Hall began to feel unwell the week before Christmas but insisted on fulfilling his duties as head chef at The Dressers Arms in Wheelton, Chorley.


http://www.theboltonnews.co.uk/news...s_agony_at_dad___s_suspected_swine_flu_death/
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Girl, 12, dies from flu bug
By Emily Pearce - Friday, January 14, 2011

THE family of a 12-year-old Wootton girl, who died following a bout of flu, have spoken of their heartbreak and paid tribute to their 'little princess?.
Dave and Annmarie Willis, of Whitehead Crescent, said they were devastated by the loss of daughter Stacey, who died at St Mary?s Hospital just after Christmas.
She had celebrated her 12th birthday with a party at the family home just five days earlier.

...

http://www.iwcp.co.uk/news/news/girl-12-dies-from-flu-bug-36738.aspx
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

(Note: Merseyside = Liverpool area)

Norris Green mother-of-two Linda Dagnall becomes 12th person on Merseyside to die of swine flu

Jan 14 2011
A 41-year-old mother-of-two from Liverpool has died of swine flu.

Linda Dagnall, of Norris Green, died in Fazakerley Hospital on January 6th. She is the 12th person known to have died of the virus on Mersesyside.

...


Read More http://www.liverpoolecho.co.uk/live...e-of-swine-flu-100252-27986070/#ixzz1B0cpiWc2
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Broadcast singer hospitalised with serious illness


Broadcast frontwoman Trish Keenan is reportedly "fighting for her life" in hospital. A co-founder of the British art-pop band, Keenan will reportedly undergo surgery after contracting H1N1 and pneumonia.

News of Keenan's illness first appeared on Broadcast's Facebook page, in a post (since removed) by Crystal Summers, who claims to be Keenan's sister. "I'm sorry everyone but I have some bad news," she wrote (via Pitchfork). "Trish Keenan is fighting for her life in hospital." After touring Australia in December, Keenan contracted the H1N1 flu, Summers said. The singer has been on a life support machine since Christmas. "She won't be singing for some time as she has to have a tube that the doctors put in her throat," Summers said. "She will have to have surgery and she won't be able to get any infections in the wound."

Broadcast's label, Warp Records, confirmed Keenan's illness to Pitchfork. "Trish is in hospital and very ill with pneumonia. At this time, please respect the privacy of the band and the family and when there is any more news [Manager] Martin [Pike] will be sure to update fans."

Broadcast's most recent album, a collaboration with the Focus Group, was released in 2009.


<a href="http://s190.photobucket.com/albums/z27/prandot/?action=view&current=Trish-Keenan-of-Broadcast-001.jpg" target="_blank"><img src="http://i190.photobucket.com/albums/z27/prandot/Trish-Keenan-of-Broadcast-001.jpg" border="0" alt="Photobucket"></a>

http://www.guardian.co.uk/music/2011/jan/14/broadcast-singer-hospitalised
 
UK Fatality Sequences Relate to US and Iran

UK Fatality Sequences Relate to US and Iran

UK Fatality Sequences Relate to US and Iran

The <strong><span style="color: #783f04;">US CDC</span></strong> today released a small set of sequences at GISAID spanning June to November 2010. As the UK Severe Wave is the current topic of interest, we have profiled 6 of these sequences from today against the UK Fatality Sequences that have been published.  Five of the sequences are <strong><span style="color: #783f04;">from the United States</span></strong> and one is from Bangladesh.

Previously, the UK HPA released a small group of sequences in two deposits at GISAID related to the present severe wave filling the ICU wards in the UK. A concurrent paper <sup><strong><span style="color: red;">1</span></strong></sup> was published in early January with a phylogenetic tree. <strong><span style="color: #783f04;">Several of the fatalities</span></strong> noted on the HPA Ellis Figure3 <sup><strong><span style="color: red;">1</span></strong></sup> phylogenetic tree have been included in the two sequence deposits.

So that focus may occur at the clinical outcomes of highest priority, <strong><span style="color: #783f04;">GeneWurx</span></strong> has prepared a fresh <a href="http://genewurx.com/data/GeneWurx_Global_Spread_of_Divergence_UK_US_Iran_v0.JPG" target="_blank">phylogenetic tree</a> with annotation in progress that may prove useful to those investigating the <strong><span style="color: #783f04;">ongoing divergency</span></strong> within this <strong><span style="color: #660000;">zoonoticly active</span></strong> <strong><span style="color: #4c1130;">pH1N1</span></strong> <a href="http://pf11.blogspot.com/2011/01/uk-and-iran-transmit-hyper-zoonotic.html" target="_blank">viral reservoir</a>.  UK Fatalities, UK Severe cases (<strong><span style="color: blue;">225G</span></strong>), UK potential Vaccine Escape cases (<strong><span style="color: blue;">158E, 159K</span></strong>) and cases from the US, Australia, Iran and Bangladesh are profiled.

<strong><a href="http://genewurx.com/data/GeneWurx_Global_Spread_of_Divergence_UK_US_Iran_v0.JPG" target="_blank">GeneWurx_Global_Spread_of_Divergence_UK_US_Iran_v0.jpg</a></strong>

The <strong><span style="color: #783f04;">GeneWurx</span></strong> annotation for the full HPA Ellis Figure3 <sup><strong><span style="color: red;">1</span></strong></sup> has been recently revised and <a href="http://genewurx.com/data/GeneWurx_UK_December_Emerging_Genetics_v5.xls" target="_blank">Version 5</a> of the Emerging Genetics spreadsheet is available with several additions including two of the recent US sequences of interest and the Bangladeshi sequence.
<ul>
<li><a href="http://genewurx.com/data/UK_2010_Phylo_ELLIS_Fig3new_4_GISAID_Notated_2011_01_13.JPG" target="_blank">UK_2010_Phylo_ELLIS_Fig3new_4_GISAID_Notated_2011_01_13.JPG</a></li>
<li><a href="http://genewurx.com/data/GeneWurx_UK_December_Emerging_Genetics_v5.xls" target="_blank">GeneWurx_UK_December_Emerging_Genetics_v5.xls</a></li>
</ul>
A pattern that has been expected is demonstrated in <strong><span style="color: #783f04;">Kentucky09_40F_2010_11_01</span></strong> with <strong><span style="color: blue;">158E, 188T</span></strong> and <strong><span style="color: blue;">225G</span></strong> on a similar background as the <strong><span style="color: #783f04;">OzBrisbane209_51F_2010_08_09</span></strong> <a href="http://pf11.blogspot.com/2010/12/ha-225g-paired-with-188t-in-diverse.html">sequence</a> carrying <strong><span style="color: blue;">156E, 188T</span></strong> and <strong><span style="color: blue;">225G</span></strong>.  Though these two sequences share extensive homology, the tree and polymorphism details will show that <strong><span style="color: #783f04;">overall the reservoir is diversifying</span></strong> and creating <strong><span style="color: #660000;">branches with minimal leaf count</span></strong> by acquiring and recombining <strong><span style="color: #660000;">rare and novel</span></strong> polymorphisms also found in <strong><span style="color: #660000;">animal reservoirs</span></strong>.

<span style="color: #274e13; font-size: x-large;">US Sequences</span>

. . . . Indiana05_78F_2010_06_11 (
. . . . . . . . 100N,
. . . . . . . . 115K,
. . . . . . . . syn270I,
. . . . . . . . 377K)

. . . . Indiana06_9M_2010_07_29 (
. . . . . . . . #11V,
. . . . . . . . #8A,
. . . . . . . . syn36L,
. . . . . . . . syn99I,
. . . . . . . . 233H,
. . . . . . . . syn256Y,
. . . . . . . . syn282C,
. . . . . . . . syn283Q,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . syn428L,
. . . . . . . . 522A)

. . . . Kentucky08_xF_2010_10_11 (
. . . . . . . . 100N,
. . . . . . . . syn179L,
. . . . . . . . 188T,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . syn448L,
. . . . . . . . 454N)

. . . . Utah05_29F_2010_10_12 (
. . . . . . . . 100N,
. . . . . . . . 188T,
. . . . . . . . 289M,
. . . . . . . . syn297N,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . 396I,
. . . . . . . . 454N,
. . . . . . . . syn478C)

. . . . Kentucky09_40F_2010_11_01 (
. . . . . . . . 17G,
. . . . . . . . 100N,
. . . . . . . . <strong><span style="color: blue;">158E</span></strong>,
. . . . . . . . syn179L,
. . . . . . . . <strong><span style="color: blue;">188T</span></strong>,
. . . . . . . . <strong><span style="color: blue;">225G</span></strong>,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . syn448L,
. . . . . . . . syn452V,
. . . . . . . . 454N,
. . . . . . . . syn467C)

<span style="color: #274e13; font-size: x-large;">Bangladesh Sequence</span>

. . . . Bangladesh8003_27M_2010_09_16 (
. . . . . . . . syn12A,
. . . . . . . . 137T,
. . . . . . . . 186P,
. . . . . . . . 225N mix wt,
. . . . . . . . syn297N,
. . . . . . . . syn326S,
. . . . . . . . syn383N,
. . . . . . . . syn388K,
. . . . . . . . 444K,
. . . . . . . . 447S,
. . . . . . . . syn474C)

<span style="color: #274e13; font-size: x-large;">UK Fatality Sequences</span>

. . . . UKEngland5040499_2010_12_f (
[match GhanaFS10_4259_2010_08_27 less 213S]
. . . . . . . . 100N,
. . . . . . . . 188T,
. . . . . . . . 213S,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . 454N,
. . . . . . . . syn537S)

. . . . UKWhiteChapel4880374_2M_2010_11_28_f (
. . . . . . . . 0A [Arizona05_2010_05_01
. . . . . . . . . . . . . . . with syn338G & 377K,
. . . . . . . . . . Alabama08_2009_12_04
. . . . . . . . . . . . . . . with syn226Q, 310A mix & 506V,
. . . . . . . . . . RussiaPerm_ZTS_2009_11_30
. . . . . . . . . . . . . . . with 377K & syn475D,
. . . . . . . . . . RussiaBelgorod01_2009_11_30,
. . . . . . . . . . RussiaBelgorod05_2009_11_30,
. . . . . . . . . . Boston634_2009_11_09
. . . . . . . . . . . . . . . with 100N & syn270I],
. . . . . . . . syn55L [S9, H5N1],
. . . . . . . . . . . . . . [Iran16273_2009_11_22 with 226R
. . . . . . . . . . . . . . NZ_Waikato2_2010_01_04 with 233H,
. . . . . . . . . . . . . . tkOntarioFAV117_1C_2009_12_07, et al],
. . . . . . . . 188T [H6N1, H7N7],
. . . . . . . . syn338G [H3N8, H4, H5, H6, sw],
. . . . . . . . . . . . . . . [OzBrisbane209_51F_2010_08_09
. . . . . . . . . . . . . . . . . . . . with 156E & 225G,
. . . . . . . . . . . . . . . Arizona05_2010_05_11 with 0A,
. . . . . . . . . . . . . . . Swine Asia 2005 with 0A, et al]
. . . . . . . . 377K,
. . . . . . . . 454N [H7N3, H7N7, H9N2]
. . . . . . . . . . [Florida14_24M_2010_08_05
. . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . FL_Pen210_2009_11_10
. . . . . . . . . . . . . . . . . . with 225E,
. . . . . . . . . . SouthCarolina18_2009_09_16_VxX
. . . . . . . . . . . . . . . . . . with 159D, 224K, et al],
. . . . . . . . syn529L)

. . . . UKCambridge118_4F_2010_11_19_f (
. . . . . . . . syn118E,
. . . . . . . . 137T [41 sequences at GISAID],
. . . . . . . . syn163K,
. . . . . . . . 186P,
. . . . . . . . syn251L,
. . . . . . . . syn293L,
. . . . . . . . syn363G [21 sequences at GISAID],
. . . . . . . . syn455Q,
. . . . . . . . syn474C,
. . . . . . . . 504G,
. . . . . . . . 513V)

. . . . UKEngland4500186_2010_11_f (
. . . . . . . . 137T (aCA) [H3N8 donor aAT, aGT, aGC],
. . . . . . . . 186P [Avian H12 2008, 2009], [Avian H1N1],
. . . . . . . . 190Y [Avian H6N1],
. . . . . . . . . . [SwedenMalmoe1_2010_01_01_xL
. . . . . . . . . . . . with 377K, syn413K,
. . . . . . . . . . Brasil7450_2009_07_22
. . . . . . . . . . . . with 157E mix wt],
. . . . . . . . 377G [H2N3],
. . . . . . . . . . . . . [H5N1 Human Egypt Preschool 2009, H5N1 Human Indonesia 2005],
. . . . . . . . . . . . . [H6N1 2009],
. . . . . . . . . . . . . [US Swine 1957-1978],
. . . . . . . . . . . . . [IranBandarAbbas5096_2010_10_02
. . . . . . . . . . . . . . . . . . . with 137T, 186P, syn474C,
. . . . . . . . . . . . . Florida13_2010_08_02
. . . . . . . . . . . . . . . . . . . with 137T, 186P, syn474C, 512M,
. . . . . . . . . . . . . . Iowa05_2010_05_04
. . . . . . . . . . . . . . . . . . . with 208K, syn516I,
. . . . . . . . . . . . . . swSouthDakota1_2010_04_27,
. . . . . . . . . . . . . . TexasAF2647_2010_04_11
. . . . . . . . . . . . . . . . . . . with 200S, syn214K, syn276H,
. . . . . . . . . . . . . . swIowa02999_2010_04_01,
. . . . . . . . . . . . . . UtahAF2653_2010_03_14
. . . . . . . . . . . . . . . . . . . with syn253V,
. . . . . . . . . . . . . . North Carolina05_2010_02_24
. . . . . . . . . . . . . . . . . . . with 259V,
. . . . . . . . . . . . . . Kentucky04_2010_02_22
. . . . . . . . . . . . . . . . . . . with syn488D,
. . . . . . . . . . . . . . Minnesota02_2010_02_17
. . . . . . . . . . . . . . . . . . . with 259V, 509D,
. . . . . . . . . . . . . . SouthCarolina01_2010_01_27
. . . . . . . . . . . . . . . . . . . with syn238E, syn488D,
. . . . . . . . . . . . . . AnasPlatBelgium04328_pcs17_2010_01_21
. . . . . . . . . . . . . . . . . . . with syn474C,
. . . . . . . . . . . . . . GermanyAF2208_2010_01_20
. . . . . . . . . . . . . . . . . . . with #1T, 225E,
. . . . . . . . . . . . . . NorthCarolina03_2010_01_20
. . . . . . . . . . . . . . . . . . . with 225G mix, 259V, syn275V,
. . . . . . . . . . . . . . NewMexico01_2010_01_05
. . . . . . . . . . . . . . . . . . . with 430I, syn445V, syn490P,
. . . . . . . . . . . . . . swThailandCU_CHK4_2009_01
. . . . . . . . . . . . . . . . . . with #1T, 0A, 189T, syn338G,
. . . . . . . . . . . . . . . . . . . . . . syn451K, syn474C, syn456L, syn529L,
. . . . . . . . . . . . . . Moldova5053_2009_12_11
. . . . . . . . . . . . . . . . . . with 173R, 176I, 225A, 225G mix wt, syn286K,
. . . . . . . . . . . . . . WiscD0128_2009_11_15
. . . . . . . . . . . . . . . . . . . with syn297N, syn343G, 471H,
. . . . . . . . . . . . . . KoreaAF2411_2009_11_11
. . . . . . . . . . . . . . . . . . . with 237I, syn286K,
. . . . . . . . . . . . . . England94840077_2009_11
. . . . . . . . . . . . . . . . . . . with 259T,
. . . . . . . . . . . . . . BahrainN11892_2009_10
. . . . . . . . . . . . . . . . . . . with 208K,
. . . . . . . . . . . . . . Nevada16_2009_10_02
. . . . . . . . . . . . . . . . . . . with 464R mix wt,
. . . . . . . . . . . . . . Tasmania2005_2009_07_03
. . . . . . . . . . . . . . . . . . . with 289M,
. . . . . . . . . . . . . . Texas42303371_2009
. . . . . . . . . . . . . . . . . . . with syn456L, syn507K],
. . . . . . . . syn408E,
. . . . . . . . syn474C,
. . . . . . . . 512M,
. . . . . . . . 530I)

. . . . UKEngland4640543_2010_11_f (
[match to UKEngland4940476_2010_12 less 225G plus 190G]
. . . . . . . . 100N,
. . . . . . . . syn179L,
. . . . . . . . 188T,
. . . . . . . . 190G,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . syn448L,
. . . . . . . . 454N)

. . . . UKWhiteChapel4780352_5M_2010_10_26_f (
. . . . . . . . syn58C,
. . . . . . . . 100N,
. . . . . . . . 128D,
. . . . . . . . syn131S,
. . . . . . . . syn210S,
. . . . . . . . 377K)

. . . . UKEngland4380108_2010_10_f (
. . . . . . . . syn67N,
. . . . . . . . 100N,
. . . . . . . . 128D,
. . . . . . . . 144V [Boston703 and Ireland],
. . . . . . . . 224K,
. . . . . . . . syn235T,
. . . . . . . . 377K,
. . . . . . . . 529M)

. . . . UKBirmingham3220137_44F_2010_08_07_f (
. . . . . . . . #8A,
. . . . . . . . 175K,
. . . . . . . . 311E,
. . . . . . . . 377K,
. . . . . . . . syn385V,
. . . . . . . . syn451K,
. . . . . . . . syn454S,
. . . . . . . . syn494E,
. . . . . . . . 537G)

<span style="color: #274e13; font-size: x-large;">Severe Sequences</span>

. . . . UKEngland4940476_2010_12 (
. . . . . . . . 100N,
. . . . . . . . syn179L (CTg) [Regional Marker 2009 (tTA)]
. . . . . . . . . . . . . . . . . . . . [TexasAF2588_2009_10_04,
. . . . . . . . . . . . . . . . . . . . TexasJMS404_2010_01_08],
. . . . . . . . 188T,
. . . . . . . . 225G,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . syn448L [H6N1]
. . . . . . . . . . . . . . . [Regional Marker UK 2009]
. . . . . . . . . . . . . . . [UKEngland4880378_2010_12 with syn179L, 188T,
. . . . . . . . . . . . . . . UKEngland4640543_2010_11_f with syn179L, 188T, 190G
. . . . . . . . . . . . . . . UKEngland4920303_2010_11 with syn179L, 188T,
. . . . . . . . . . . . . . . UKEngland142_2010_11 with syn179L, 188T,
. . . . . . . . . . . . . . . UKEngland4860049_2010_11 with syn179L, 188T,
. . . . . . . . . . . . . . . UKEngland126_2010_11 with syn179L, 188T,
. . . . . . . . . . . . . . . NZChristchurch8_2010_07_08
. . . . . . . . . . . . . . . . . . . with syn44L, 97N, syn99I, syn106E, 128D,
. . . . . . . . . . . . . . . . . . . . . . . syn214K, 253A, syn362S, 377K,
. . . . . . . . . . . . . . . Calif06_2010_04_05 with 269V
. . . . . . . . . . . . . . . Hawaii08_2010_04_12
. . . . . . . . . . . . . . . . . . . with 159D, 269V, 312R, 313K,
. . . . . . . . . . . . . . . Ethiopia13_2010_02_10
. . . . . . . . . . . . . . . . . . . with 100N, syn163K, 269V, 324I, syn360Q, syn455Q,
. . . . . . . . . . . . . . . Philippines824_2010_02_17 with 165N,
. . . . . . . . . . . . . . . Kosova876_2009_12_22,
. . . . . . . . . . . . . . . RussiaYakutsk_EAV_2009_11_18,
. . . . . . . . . . . . . . . Netherlands2143_2009_11_16 with syn179L (tTA),
. . . . . . . . . . . . . . . RussiaYaroslavl_CHMV_2009_11_10_f with 224K & 225G mix
. . . . . . . . . . . . . . . AntwerpINS221_2009_10_28 with syn179L (tTA)],
. . . . . . . . 454N)

. . . . UKEngland4880378_2010_12 (
. . . . . . . . 100N,
. . . . . . . . syn179L,
. . . . . . . . 188T,
. . . . . . . . 225G,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . syn448L,
. . . . . . . . 454N)

<span style="color: #274e13; font-size: x-large;">Potential Vaccine Escape Sequences</span>

[<a href="http://pf11.blogspot.com/2011/01/uk-severe-wave-demonstrates-diversity.html" target="_blank">Diversity with Vaccine Escape Potential</a>]

. . . . UKEngland106_2010_11 (
. . . . . . . . 0A,
. . . . . . . . syn55L,
. . . . . . . . 158E mix wt,
. . . . . . . . 188T,
. . . . . . . . syn258F,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . 452I [],
. . . . . . . . 454N,
. . . . . . . . syn529L)

. . . . UKEngland3380426_2010_08 (
. . . . . . . . syn44L,
. . . . . . . . syn106E,
. . . . . . . . 128D,
. . . . . . . . 159K [NY3230_2010_01_25 with 100N, syn177L, syn231N],
. . . . . . . . 377K)

<span style="color: #274e13; font-size: x-large;">Iran Sequences</span>

. . . . IranShahriar5336_2010_12_06 (
. . . . . . . . 137T (aCA) [H3N8 donor aAT, aGT, aGC],
. . . . . . . . 186P [Avian H12 2008, 2009], [Avian H1N1],
. . . . . . . . syn297N [H3N8 gadwallRussiaAltai1325_2007_09],
. . . . . . . . . . . . . . . [H5N1],
. . . . . . . . . . . . . . . [Wisconsin08_2010_08_10
. . . . . . . . . . . . . . . . . . . . . . with 39R, syn78S, 137T, 186P, syn297N,
. . . . . . . . . . . . . . . . . . . . . . . . . . syn326S, syn346G, syn388K,
. . . . . . . . . . . . . . . . . . . . . . . . . . syn413K, 444K, syn474C,
. . . . . . . . . . . . . . . CalifVRDL2_2010_01_11
. . . . . . . . . . . . . . . . . . . . . . with syn121P & 502K,
. . . . . . . . . . . . . . . YaroslavlIIV196_2009_12_04_f
. . . . . . . . . . . . . . . . . . . . . . with syn159N, 225G,
. . . . . . . . . . . . . . . WiscD0128_2009_11_15
. . . . . . . . . . . . . . . . . . . . . . with syn343G, 377G, 471H,
. . . . . . . . . . . . . . . Brussels243_2009_11_09
. . . . . . . . . . . . . . . . . . . . . . with syn44L, syn159N & syn323N,
. . . . . . . . . . . . . . . Australia6_2009_07_18
. . . . . . . . . . . . . . . . . . . . . . with syn159N, 233H]
. . . . . . . . syn326S [Wisconsin08_2010_08_10
. . . . . . . . . . . . . . . . . . . . . . with 39R, syn78S, 137T, 186P, syn297N,
. . . . . . . . . . . . . . . . . . . . . . . . . . syn326S, syn346G, syn388K,
. . . . . . . . . . . . . . . . . . . . . . . . . . syn413K, 444K, syn474C,
. . . . . . . . . . . . . . . Zhongyuan1643_2009_11_16
. . . . . . . . . . . . . . . . . . . . . . with 208G],
. . . . . . . . syn383N [H3N8],
. . . . . . . . syn388K [H3N8, H5N1, S7],
. . . . . . . . . . . . . . . [OzVictoria508_2010_07_24
. . . . . . . . . . . . . . . . . . . . . . . with 238D,
. . . . . . . . . . . . . . . swIowa44837_1_2009_11_08_xL
. . . . . . . . . . . . . . . . . . . . . . . with 188R, 225N & 230I,
. . . . . . . . . . . . . . . Utah20_C2_2_2009_07_25_VxX
. . . . . . . . . . . . . . . . . . . . . . . with 159D & 227G, et al],
. . . . . . . . syn411N (AAc) [H7N3 & H7N7 donor ATc],
. . . . . . . . 444K (AAg) [H3N8 gAg],
. . . . . . . . syn474C [H3N8, Avian H1N1 2010],
. . . . . . . . . . . . . . . [Michigan10_2009_06_03 with 137T, 225N, et al])

. . . . IranBandarAbbas5096_2010_10_02 (
. . . . . . . . 72P,
. . . . . . . . 137T (aCA) [H3N8 donor aAT, aGT, aGC],
. . . . . . . . 186P [Avian H12 2008, 2009], [Avian H1N1],
. . . . . . . . syn318A,
. . . . . . . . 377G [H2N3],
. . . . . . . . . . . . . [H5N1 Human Egypt Preschool 2009, H5N1 Human Indonesia 2005],
. . . . . . . . . . . . . [H6N1 2009],
. . . . . . . . . . . . . [US Swine 1957-1978],
. . . . . . . . . . . . . [Florida13_2010_08_02
. . . . . . . . . . . . . . . . . . . with 137T, 186P, syn474C, 512M,
. . . . . . . . . . . . . . Iowa05_2010_05_04
. . . . . . . . . . . . . . . . . . . with 208K, syn516I,
. . . . . . . . . . . . . . swSouthDakota1_2010_04_27,
. . . . . . . . . . . . . . TexasAF2647_2010_04_11
. . . . . . . . . . . . . . . . . . . with 200S, syn214K, syn276H,
. . . . . . . . . . . . . . swIowa02999_2010_04_01,
. . . . . . . . . . . . . . UtahAF2653_2010_03_14
. . . . . . . . . . . . . . . . . . . with syn253V,
. . . . . . . . . . . . . . North Carolina05_2010_02_24
. . . . . . . . . . . . . . . . . . . with 259V,
. . . . . . . . . . . . . . Kentucky04_2010_02_22
. . . . . . . . . . . . . . . . . . . with syn488D,
. . . . . . . . . . . . . . Minnesota02_2010_02_17
. . . . . . . . . . . . . . . . . . . with 259V, 509D,
. . . . . . . . . . . . . . SouthCarolina01_2010_01_27
. . . . . . . . . . . . . . . . . . . with syn238E, syn488D,
. . . . . . . . . . . . . . AnasPlatBelgium04328_pcs17_2010_01_21
. . . . . . . . . . . . . . . . . . . with syn474C,
. . . . . . . . . . . . . . GermanyAF2208_2010_01_20
. . . . . . . . . . . . . . . . . . . with #1T, 225E,
. . . . . . . . . . . . . . NorthCarolina03_2010_01_20
. . . . . . . . . . . . . . . . . . . with 225G mix, 259V, syn275V,
. . . . . . . . . . . . . . NewMexico01_2010_01_05
. . . . . . . . . . . . . . . . . . . with 430I, syn445V, syn490P,
. . . . . . . . . . . . . . swThailandCU_CHK4_2009_01
. . . . . . . . . . . . . . . . . . with #1T, 0A, 189T, syn338G,
. . . . . . . . . . . . . . . . . . . . . . syn451K, syn474C, syn456L, syn529L,
. . . . . . . . . . . . . . Moldova5053_2009_12_11
. . . . . . . . . . . . . . . . . . with 173R, 176I, 225A, 225G mix wt, syn286K,
. . . . . . . . . . . . . . WiscD0128_2009_11_15
. . . . . . . . . . . . . . . . . . . with syn297N, syn343G, 471H,
. . . . . . . . . . . . . . KoreaAF2411_2009_11_11
. . . . . . . . . . . . . . . . . . . with 237I, syn286K,
. . . . . . . . . . . . . . England94840077_2009_11
. . . . . . . . . . . . . . . . . . . with 259T,
. . . . . . . . . . . . . . BahrainN11892_2009_10
. . . . . . . . . . . . . . . . . . . with 208K,
. . . . . . . . . . . . . . Nevada16_2009_10_02
. . . . . . . . . . . . . . . . . . . with 464R mix wt,
. . . . . . . . . . . . . . Tasmania2005_2009_07_03
. . . . . . . . . . . . . . . . . . . with 289M,
. . . . . . . . . . . . . . Texas42303371_2009
. . . . . . . . . . . . . . . . . . . with syn456L, syn507K],
. . . . . . . . syn449Y (TAc) [H3N8 Ttc],
. . . . . . . . syn474C [H3N8])

. . . . IranKaraj5327_2010_12_06 (
. . . . . . . . syn34N [JapanKanagawa74_2010_10_16, et al],
. . . . . . . . 146G [JapanKanagawa74_2010_10_16, et al],
. . . . . . . . 188T,
. . . . . . . . 200T,
. . . . . . . . syn338G,
. . . . . . . . 377K,
. . . . . . . . 454N,
. . . . . . . . syn465N [OzBrisbane209_51F_2010_08_09,
. . . . . . . . . . . . . . . . . . . . with 156E & 225G,
. . . . . . . . . . . . . . CalifVRDL131_2009_12_30, et al],
. . . . . . . . syn538F [Brunei218_2010 with 188T])

<span style="color: #274e13; font-size: x-large;">Australia Sequence</span>

. . . . OzBrisbane209_51F_2010_08_09 (
. . . . . . . . <strong><span style="color: blue;">156E</span></strong> [H2N3, <strong><span style="color: #660000;">H3N8</span></strong>, <strong><span style="color: #660000;">H5N1</span></strong>, H10N7],
. . . . . . . . <strong><span style="color: blue;">188T</span></strong> [H6N1, <strong><span style="color: #660000;">H7N7</span></strong>],
. . . . . . . . <strong><span style="color: blue;">225G</span></strong>,
. . . . . . . . syn338G [<strong><span style="color: #660000;">H3N8</span></strong>, H4, H5, H6, sw],
. . . . . . . . . . . . . . . [OzVictoria670_30M_2010_11_14
. . . . . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . . . . . . Emergent across Australia
. . . . . . . . . . . . . . . . . . . . . during late 2010 season,
. . . . . . . . . . . . . . . Florida14_24M_2010_08_05
. . . . . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . . . . . . OZVictoria512_2010_07_30
. . . . . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . . . . . . NZChristchurch15_2010_07_12
. . . . . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . . . . . . India5107_2010_06_28
. . . . . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . . . . . . MississippiAF2474_2010_03_10
. . . . . . . . . . . . . . . . . . . . . with syn235T,
. . . . . . . . . . . . . . . FloridaAF2197_2010_03_07
. . . . . . . . . . . . . . . . . . . . . with 156T,
. . . . . . . . . . . . . . . CalifVRDL9_2010_02_09
. . . . . . . . . . . . . . . . . . . . . with syn193S,
. . . . . . . . . . . . . . . Georgia06_2010_02_05
. . . . . . . . . . . . . . . . . . . . . with syn161Y,
. . . . . . . . . . . . . . . NY4662_2010_02_03
. . . . . . . . . . . . . . . . . . . . . with 97N, syn276H, syn283Q, syn304G,
. . . . . . . . . . . . . . . TexasJMS406_2010_01_10
. . . . . . . . . . . . . . . . . . . . . with 187A, syn193S, syn283Q,
. . . . . . . . . . . . . . . TexasJMS405_2010_01_09
. . . . . . . . . . . . . . . . . . . . . with 187A, syn283Q,
. . . . . . . . . . . . . . . CalifVRDL131_2009_12_30
. . . . . . . . . . . . . . . . . . . . . with 225G, syn455Q,
. . . . . . . . . . . . . . . LouisianaAF2435_2009_11_30
. . . . . . . . . . . . . . . . . . . . . with syn13N,
. . . . . . . . . . . . . . . Vienna291_2009_11_19
. . . . . . . . . . . . . . . catOregon29573_2009_11_09
. . . . . . . . . . . . . . . . . . . . . with 226R, syn283Q,
. . . . . . . . . . . . . . . Calif_SanDiegoINS63_2009_10_26
. . . . . . . . . . . . . . . . . . . . . with syn283Q, et al],
. . . . . . . . 377K,
. . . . . . . . 454N [H7N3, <strong><span style="color: #660000;">H7N7, H9N2</span></strong>]
. . . . . . . . . . [Florida14_24M_2010_08_05
. . . . . . . . . . . . . . . . . . with 188T, 454N,
. . . . . . . . . . FL_Pen210_2009_11_10
. . . . . . . . . . . . . . . . . . with 225E,
. . . . . . . . . . SouthCarolina18_2009_09_16_VxX
. . . . . . . . . . . . . . . . . . with 159D, 224K,
. . . . . . . . . . Texas45131774_2009_09_13
. . . . . . . . . . . . . . . . . . with syn223V,
. . . . . . . . . . IndiaPune9355_2009_08
. . . . . . . . . . . . . . . . . . with 225G,
. . . . . . . . . . IndiaBlore236_2009_06_xL
. . . . . . . . . . . . . . . . . . with 226R, et al],
. . . . . . . . syn465N)


<span style="font-size: x-small;"><strong><span style="color: red;">1.</span></strong> Ellis J, Galiano M, Pebody R, Lackenby A, Thompson C, Bermingham A, McLean E, Zhao H, Bolotin S, Dar O, Watson JM, Zambon M. Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11. Euro Surveill. 2011;16(1):pii=19760. Available online: </span><a href="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19760" target="_blank"><span style="font-size: x-small;">http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19760</span></a>
 
Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (173 reported fatalities), 800+ Patients in intensive care due to influenza

Swine flu mother tells of battle to survive





A new mother who nearly died from swine flu and needed an emergency caesarean to save her baby has urged all pregnant women to get vaccinated.

Lynsey Frew, 29, from Rigside in Lanark, fell ill on Boxing Day with flu-like symptoms when she was eight months pregnant.

Her condition deteriorated and on Hogmanay she was rushed by ambulance to Wishaw General.

By late on New Year's Day, however, she could no longer breathe for herself.

Hours later, staff at the hospital performed an emergency caesarean operation to save her unborn daughter.

Sarah Frew Lane was born seven weeks early and taken to the neonatal unit.

Meanwhile, Ms Frew began her battle for survival in the intensive care unit (ICU).

The student nurse, who attends the University of the West of Scotland, said she was certain she would die without meeting her child.


http://www.bbc.co.uk/news/uk-scotland-12192092
 
Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

[Source: World Health Organization, full page: http://www.who.int/csr/disease/influ.../en/index.html - http://www.flutrackers.com/forum/sho...72&postcount=1. Edited.]

Influenza update - 14 January 2011

Influenza - Update 125

14 January 2011


(...)


Summary:

(...)

In the United Kingdom, severe and fatal cases are increased compared to 2 weeks ago, associated predominantly with influenza A (H1N1) 2009 and less commonly with influenza type B.

Currently, 25% of intensive care beds in the U.K. are occupied by influenza patients.

Quote:
<table border="0" cellpadding="6" cellspacing="0" width="100%"> <tbody><tr> <td class="alt2" style="border: 1px inset ;"> Notably, the Chief Medical Officer has issued an alert to clinicians warning of increasing rates of bacterial infections often associated with influenza (S. pneumoniae, Group A streptococcus, and meningococcus), though the association with the current influenza circulation is still under investigation. </td> </tr> </tbody></table>
(...)

Europe:

The United Kingdom (U.K.) continues to report high rates of ILI and influenza-related hospitalizations.

Currently approximately 25% of intensive care beds are occupied by influenza cases and 112 influenza-related deaths have been reported.

95 of 100 fatal cases from which the virus has been sub-typed have been H1N1 (2009) related and the other 5, influenza type B.

The majority of severe and fatal cases have been between the ages of 15 and 64 years; only 16% of fatal cases were over the age of 64 years.

Quote:
<table border="0" cellpadding="6" cellspacing="0" width="100%"> <tbody><tr> <td class="alt2" style="border: 1px inset ;"> 78% of the fatal cases for which there are data had an underlying risk condition. </td> </tr> </tbody></table>
Of note, the Chief Medical Officer of the U.K. has issued an alert to clinicians noting recent increases in some bacterial infections that are sometimes seen as co-infections with influenza, particularly S. pneumoniae, invasive Group A streptococcus, and meningococcal disease.

The association of this increase with the current influenza transmission is unclear and is under investigation.

Quote:
<table border="0" cellpadding="6" cellspacing="0" width="100%"> <tbody><tr> <td class="alt2" style="border: 1px inset ;"> Two percent (17/811) H1N1 (2009) viruses tested in the U.K. have been found to carry the H275Y mutation which confers resistance to the antiviral drug oseltamivir. </td> </tr> </tbody></table>
(...)
.
......
 
Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

2% Oseltamivir resistance is a point of evaluation and may provide the spark for spread depending on regionality and sub-clinical usage policies.
 
Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

An 86-year-old woman has died from swine flu at Wolverhampton?s New Cross Hospital ? the third victim of the virus in the city since December.


Third Wolverhampton swine flu death
Saturday 15th January 2011, 10:23AM GMT.

An 86-year-old woman has died from swine flu at Wolverhampton?s New Cross Hospital ? the third victim of the virus in the city since December

The hospital confirmed the pensioner died yesterday morning after losing her battle with the virus in the critical care unit.

Although the death has been attributed to swine flu the hospital said the woman was suffering from an underlying respiratory disease.

It has also been confirmed that a man in his 50s who died at Stafford Hospital on Monday was suffering from the virus.

A woman in her 70s died at New Cross on December 27 and a man aged 52, died on December 30. Both had underlying medical problems.

...

Read more: http://www.expressandstar.com/news/2011/01/15/third-wolverhampton-swine-flu-death/#ixzz1B6RxgePT
 
Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Shock as man killed by swine flu
Friends pay tribute to Stonehaven digger operator
By Alison Rennie

Published: 15/01/2011


LOSS: Digger operator Gerald Matthew, from Stonehaven, died after catching swine flu.
More Pictures

A MAN has died after being hit by swine flu, the Evening Express can reveal today.

Gerald Matthew, 42, of Stonehaven, died after he was rushed to hospital with flu symptoms diagnosed as the deadly H1N1 virus.

...

Read more: http://www.eveningexpress.co.uk/Article.aspx/2092331?UserKey=#ixzz1B6SV89Cj
 
Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Healthy Norris Green mum-of-two is latest swine flu victim

by Liza Williams, Liverpool EchoJan 15 2011
http://www.liverpooldailypost.co.uk...-is-latest-swine-flu-victim-100252-27989218/?

A HEALTHY mum-of-two was the latest victim of the swine flu outbreak in Merseyside.

Linda Dagnall, 41, from Norris Green, died at Fazakerley hospital on January 6.

Gerard Walker, her partner of 22 years, said the ?love of my life? was an otherwise a healthy woman.

.....
 
Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Re: UK: 112 confirmed fatalities (179 reported fatalities), 800+ Patients in intensive care due to influenza

Two children with swine flu die


Two young children with swine flu have died in Northern Ireland.

The death of a 10-month-old baby boy was announced just hours after the authorities said a two-year-old boy with the virus had died.

The baby had underlying health problems.

It is not known if the two-year-old, who was from the Republic of Ireland, was also suffering from another condition as his family have asked for those details to remain private.

The death takes to 19 the confirmed number of people with the H1N1 virus who have died in Northern Ireland this flu season.

Health Minister Michael McGimpsey expressed his sympathies to the family of the latest young victim, who was from Northern Ireland.

"This is tragic news and my thoughts and sympathies are with the family of this baby at this very sad and difficult time," he said.

The minister had earlier passed his condolences to the family of the two-year-old boy.

The fatalities will put further pressure on the authorities to re-think the policy decision not to vaccinate all under-fives against the virus, something which was done last year. Only infants in 'at-risk' health categories are being vaccinated.

But after the death of the two-year-old was announced, Mr McGimpsey said medical advisers remained of the opinion that the vaccination programme should not be extended

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