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Omicron - COVID-19 Variant (B.1.1529) a "Variant of Concern" & BA.2 sub-variant, XE

I have a problem with people who post anonymously calling other people, who are putting their professional reputations on the line publicly every time they post, names. It is not ethical. A lot of experts disagree on many topics. It is not necessary to bash to get the point across.
 
As a bit of background. The MHC type 1 cell surface receptor is made up of proteins which are coded for in an allele which is part of the HLA. For different HLAs these proteins will vary giving a slightly different binding affinity between the MHC, which presents the viral antigen and has a CD8 receptor, to the T cell antibody and its CD8 cell surface protein. The same applies to the MHC2 receptor which binds CD4 T cells & antibodies, but with a slightly longer antigenic peptide, giving a little more specificity. CD8 T cells are involved in killing infected cells while CD4 T cells help with B cell differentiation/class switching and antibody refinement.
 
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There is some major irony here saying this guy "is a known source of propaganda". Read all of the article at the ink that Emily posted. Especially the last couple of sentences.
 
He does have a financial interest in all this, and Anderson has been involved in nasty tactics to suppress consideration of the lab-leak possibility for sars-cov-2. Read about the wearable sensor technology.

xhttps://www.scripps.edu/news-and-events/press-room/2021/20210614_radin_rockefeller-aws.html
"Eric Topol, MD, founder and director of the Scripps Research Translational Institute, contributed to The Rockefeller Foundation’s National COVID-19 Testing Action Plan, as well as an updated version of the report. Topol and Kristian Andersen, PhD, director of Infectious Disease Genomics at SRTI, also provided their expertise for the Foundation’s national disease surveillance plan, which calls for using genomic technologies and other sophisticated tools to detect and track viral threats. "
 
strange,unexpected,big decline in infections and positive-rates and
-to lower degree- also hospitalisations in the last 2 days.
NICD has data issues and we have weekend, but that doesn't really seem to explain it.
I.e. the positive rate should not be affected.
And not in all provinces ?!

But what else could be the reason ? Tshwane is 1 week ahead of Gauteng
and Gauteng is 1 week ahead of other provinces, so I'd expect it to
peak in Tshwane first.
https://twitter.com/gsgs2/status/1469879399369609222

https://twitter.com/BallouxFrancois/...33674426023936
https://twitter.com/tomtom_m/status/1469954026347315211

http://magictour.free.fr/zaf2i.GIF
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5,?,26,67,105,150,?,242,368,504,624,?,954 daily omicrons at cog_UK
1,1,3,7,7,19,40,65,31,81,100,107,118,125,150,74,13 ,12 by collection date since Nov20
more than delta in 18 days with this trend (slows down a bit)
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maybe older people are protected against omicron from multiple previous exposures to other cold-(corona) viruses
which were circulating decades ago ?!?
we saw that with flu
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we could/should have created an omicron-like virus in the lab , more transmissable less virulent
maybe after this wave such strategies will be developed (H5N1)
But we must reach an international consensus and surveillance, because it could lead
to new manmade pandemics
 
There is another reason that could explain this - there is a mutation that s causing a second target failure - this would explain why positive test results are being affected while they confirm what is going on with samples that only showed one target.

edit - this is just a hypothesis that I dreamt up - I have not seen any evidence
 
https://www.theguardian.com/world/2...ovid-patients-in-hospital-government-confirms
UK has Omicron Covid patients in hospital, government confirms

Top UK medical adviser says growing number of people going to emergency departments diagnosed with Omicron

People have been admitted to hospital with the Omicron variant in Britain, a government minister has confirmed, as a senior public health adviser said further curbs may be needed.

The education secretary, Nadhim Zahawi, said he could confirm there were “cases in hospital with Omicron”. “We’ve been able to test people who are in hospital over the past two weeks, and so there is a lag to hospitalisation,” he told Trevor Phillips on Sky News.


Speaking to the BBC, Susan Hopkins, the chief medical adviser of the UK Health Security Agency, said hospitals were diagnosing Omicron in an increasing number of people coming into emergency departments and that the numbers in hospital were expected to increase.

No deaths have been reported so far from Omicron, although it is just over two weeks since the variant was first detected in the UK, and there is normally a time lag of three to four weeks between infection and death, should that happen. “I think it’s too early to make any assumption at this point in time,” Hopkins said.
 
---------------edit 2021-12-13------------------
backlog now. Yesterday's decline was not real.
Balloux deleted his thread, NICD apologizes, no comment by Moultrie yet.
It's still not exponential, more linear, but still growing
https://www.nicd.ac.za/latest-confirmed-cases-of-covid-19-in-south-africa-12-december-2021/
More backlogs expected
https://twitter.com/nicd_sa/status/1470128000746274820

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IMO they should include estimates, what the real numbers are
in general
WHO,CDC,RKI,ECDC,
UN,.gov, - whatever
can be just one letter, if the estimate coincides with the given numbers
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CDC Predicts U.S. COVID Deaths Will Rise As Britain Reports First Omicron Death

BY JENNI FINK ON 12/13/21 AT 10:53 AM EST
...
It's unclear what impact Omicron will have on hospitalizations and deaths, though. Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), told the Agence France-Presse the "best-case scenario" would be Omicron being highly transmissible but a variant that causes only mild disease.

Omicron causing mild disease could help the world avoid the surge in hospitalizations and deaths that Delta's fueling, according to Fauci.

However, Daniel Havlichek, former Chief of the College of Human Medicine's Infectious Diseases Division at Michigan State University, noted that if Omicron is 10 times more transmissible but only causes severe disease in one-tenth the people, there could be the same number of deaths by raw numbers. WHO COVID-19 technical lead Maria van Kerkhove also raised concerns about people getting complacent if Omicron is less severe than Delta.

Even if most people only have a mild illness, van Kerkhove told Face the Nation that a highly transmissible variant will increase the number of infections and as cases rise, so will hospitalizations because some people will get seriously ill.
...
https://www.newsweek.com/cdc-predict...-death-1658772
 
Danish Omicron case study just published. About 3,400 cases. Very interesting. Hospitalization rate is a bit greater than other variants. Primarily attacking 20-29 yr old category (unexpected!), and fewer cases among the 64+ yr old category (unexpected to me). Vaccine evasion is about twice the rate as other variants. Rapport om omikronvarianten https://t.co/ZstMAZZ2bd
 
Yikes. I have seen data that contradicts the case that Omicron is mild, however, this takes it to a whole new level of showing that it is putting more people in the hospital than existing strains. I would imagine that people in their 20's tend to have more social contact, spend more time in restaurants, and a more rebellious against masks than other age groups. Just a hypothesis but that would explain the huge spike in cases in their 20's.
 
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