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Egypt Human Cases Feb 25th - April 19th 2008

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Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Commentary http://www.recombinomics.com/feed.xml http://www.newsnow.co.uk/nn/Recombinomics

Hospitalized Suspect H5N1 Patients in Egypt


Recombinomics Commentary 19:36
March 5, 2008

The case is an 11-year-old male from Menof District, Menofia Governorate. He was hospitalized with symptoms on 26 February and was confirmed as being infected with A(H5N1) by the Central Public Health Laboratory and NAMRU-3 on 4 March. He remains in a critical condition.

To the present, the hospital dietary and chest in a large number of provinces, yesterday, the detention of dozens of cases suspected of carrying avian influenza.

The above comments on the latest confirmed case in Egypt are from the latest WHO update, confirming that the case is in critical condition. Thus, all three recent confirmed cases have developed pneumonia. One (25F) has died, one (11M) is in critical condition, and one (4F) is in stable condition.

However, the above translation from local media describes a large number of hospitalized suspect cases. It is unclear if these additional cases have also develop pneumonia, or if they are hospitalized as a precaution. Earlier this year large numbers of patients were hospitalized following confirmation of H5N1 cases in late December. Those cases did not test positive for H5N1 and many were said to have had seasonal flu. Thus, the coincidence with seasonal flu season at this time may indicate that these are patients hospitalized due to an abundance of caution.

More details on the condition of these patients, including their pneumonia status, would be useful.


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Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

New confirmed human influenza case in Egypt
Case number: 46

Reported on 4 March 2008

The Ministry of Health and Population of Egypt has declared a new H5N1 human case no. 46, a male, 11 year old, from Sedod Village, Menof district, Menofia Governorate. The case is still alive and was diagnosed with H5N1 on 4 March 2008 by Central Public Health Laboratory, MOH, and confirmed by NAMRU-3. The case was hospitalized in Menof Fever Hospital on 26 February suffering from Chest Infection. The family denied any history of contact with poultry. The case was suspected on the 2nd of March after sings of pneumonia which appeared in chest x-ray (bilateral) and referred to Manshyet El-Bakry General Hospital on the 4<SUP>th</SUP> of March. Field investigation conducted on the same day indicated history of contact with sick and dead poultry. The general condition of the patient is critical and the child is not yet on ventilator.
This brings up the total number of confirmed human cases of avian influenza in Egypt to 46 with 20 deaths.

Update on case Number 45
(Fayum Governorate)

The National IHR Focal Point in the Ministry of Health and Population of Egypt reported the death of Fayum case No.45 on 4 March 2008. This brings up the total number of death from avian influenza infection in Egypt to 20 deaths
(Number of cases=45; Number of deaths=20).


http://www.emro.who.int/csr/ai_46_4_03_08.htm
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

AVIAN INFLUENZA, HUMAN (34): EGYPT, WHO
***************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: Wed 5 Mar 2008
Source: World Health Organization (WHO) Epidemic and Pandemic Alert
and Response (EPR) disease outbreak news [edited]
<http://www.who.int/csr/don/2008_03_05/en/index.html>


Egypt: avian influenza situation - WHO update 6
-----------------------------------------------
The Ministry of Health and Population of Egypt has announced a new
human case of avian influenza A(H5N1) virus infection. The case is an
11-year-old male from Menof District, Menofia [Al Minufiyah]
governorate. He was hospitalized with symptoms on 26 Feb 2008 and was
confirmed as being infected with A(H5N1) by the Central Public Health
Laboratory and NAMRU-3 on 4 Mar 2008. He remains in critical condition.

Investigations into the source of his infection indicate a history of
contact with sick and dead poultry.

Of the 46 cases confirmed to date in Egypt, 20 have been fatal.

--
Communicated by:
ProMED-mail Rapporteur Marianne Hopp

[A map of the governorates (provinces) of Egypt can be accessed at
<http://www.map-of-egypt.org/map-of-egypt.gif>. Al Minufiyah
governorate lies in the populous Nile delta region just north of
Cairo. - Mod.CP]

[see also:
Avian influenza, human (33): Egypt, WHO 20080305.0900
Avian influenza, human (32): Egypt, WHO 20080302.0849
Avian influenza, human (31): China, Egypt, Viet Nam, WHO 20080226.0784
Avian influenza, human (07): Egypt 20080113.0171
Avian influenza, human (03): Egypt, Pakistan, WHO 20080104.0038
Avian influenza, human (02): Egypt, Viet Nam 20080103.0029
Avian influenza, human: Egypt 20080101.0006
2007
----
Avian influenza, human (180): Egypt 20071231.4194
Avian influenza, human (179): Egypt 20071230.4183
Avian influenza, human (178): Egypt, Viet Nam, WHO 20071228.4163
Avian influenza, human (177): Pakistan, Viet Nam, Egypt 20071227.4152
Avian influenza, human (176): Egypt, Indonesia, Viet Nam, WHO 20071226.4146]
...................................cp/mj/dk
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Map showing the location of the town (Sidud, Sudud, Sedod) where 11-year old Mohamed Rabia Mohammed Abdulhamid was from.


Egypt Sudud overview 20080306.jpg

Egypt Sudud Closeup 20080306.jpg
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Does the above indicate there are currently dozens of hospitalized suspect cases, or simply indicate that cummulatively, the hospital has treated dozens of suspect cases?


My contact in Egypt says the meaning is that the hospitals in many governates have cumulatively tested/treated/investigated many suspect cases.
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

My contact in Egypt says the meaning is that the hospitals in many governates have cumulatively tested/treated/investigated many suspect cases.
Thanks, Florida1! :)

That's actually very useful to know -- not just for the situation now, but in order to interpret any comments like that in the Egyptian press in the future.
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Mother and daughter suspected cases in Menya/Minya governorate.

Google-translated from Arabic:

Reservation mother and daughter modules on suspicion of injured bird flu

Menya - Nabil Yousef:

Reservation was a mother and her daughter on suspicion of injured bird flu Valley.

Major General Muhammad received Noureddine Security Chief Menya notification from the hospital salt Menya seizure of Marsa behind George 35 years of bad Ebeid modules and daughter Orlen Club Massoud 4 years on suspicion of injured bird flu sample was taken and sent to their labs and Health Ministry in Cairo.

Commissioned Major General Fuad Saad Eddin governorate of Menya Directorate of Veterinary Medicine follow-up cases.

http://www.algomhuria.net.eg/almessa/today/accedents/detail07.asp [<< not a permalink]
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Mother and daughter suspected cases in Menya/Minya governorate.

Google-translated from Arabic:

Reservation mother and daughter modules on suspicion of injured bird flu

Menya - Nabil Yousef:

Reservation was a mother and her daughter on suspicion of injured bird flu Valley.

Major General Muhammad received Noureddine Security Chief Menya notification from the hospital salt Menya seizure of Marsa behind George 35 years of bad Ebeid modules and daughter Orlen Club Massoud 4 years on suspicion of injured bird flu sample was taken and sent to their labs and Health Ministry in Cairo.

Commissioned Major General Fuad Saad Eddin governorate of Menya Directorate of Veterinary Medicine follow-up cases.

http://www.algomhuria.net.eg/almessa/today/accedents/detail07.asp [<< not a permalink]
Any news on transfer to Cairo or details on their condition?
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Any news on transfer to Cairo or details on their condition?
No. I checked all the Egyptian papers that I normally "read" and this was the only story about this mother & daughter -- and it was tucked away on a back page of Al Messa.

It is Saturday and that is a very slow news day in Egypt (like Sunday for us).
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Egyptian boy confirmed with bird flu, 47th case

Sat 8 Mar 2008, 16:21 GMT

[-] Text [+] CAIRO, March 8 (Reuters) - An 8-year-old boy in Fayoum province has contracted the bird flu virus after coming into contact with infected birds -- the 47th case among humans in Egypt since 2006, the Health Ministry said on Saturday.

The boy, Abdel Hamid el-Sayed Youssef, was taken to a local hospital with a high temperature, difficulty breathing and a pulmonary inflammation, spokesman Abdel Rahman Shahine said in a statement.

He moved to a Cairo hospital on Friday and is being treated with Tamiflu, the standard treatment for humans, it said.

An Egyptian woman from the same province southwest of Cairo died of the disease last week but a health official said there did not appear to have been contact between them.

Altogether 20 people have died of bird flu in Egypt since it arrived in the country in February 2006.

It is the third winter the virus has struck after lying low during Egypt's hot summers.

Around 5 million households in Egypt depend on poultry as a main source of food and income, and the government has said this makes it unlikely the disease can be eradicated despite a large-scale poultry vaccination programme.

Deaths from bird flu total more than 230 worldwide since 2003 and have been reported in several African and Asian countries. Egypt has been the worst-hit country outside of Asia. (Writing by Jonathan Wright, editing by Mary Gabriel)

http://africa.reuters.com/wire/news/usnL087754.html
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Dr. Niman, can you explain a little more about these non synonymous changes?
From your commentary:
These isolates had a large number of non synonymous changes, including P78S, D101N, H114R, S127P, R144G, S145P, F148Y, R166K, N166H, A189E, and M230V. This high number of protein changes raise concerns of accelerated H5N1 evolution due to vaccine escape.

Moreover, these changes were present in additional isolates collected from additional locations, including Kom-Hammada, Behera (A/chicken/Egypt/07701S-NLQP/2007), Mansura, Dakahlia (A/chicken/Egypt/088S-NLQP/2008), and Ghamr, Dakahlia (A/chicken/Egypt/86Q-NLQP/2008), indicating this sub-clade is widespread in Egypt.

From this commentary:
Recombinomics Commentary 05:21
March 2, 2008

Included in this collection are H5N1 sequences from vaccinated flocks. These sequences have an alarming number of new polymorphisms, most of which are non synonymous. As noted earlier, the sequences released from NAMRU-3 had a number of non synonymous changes at targeted positions. The sequences from the National Lab extend these observations.

There are now multiple positions which have changed to two or more amino acids. Position 144 which had changed to three different amino acids (R144K, R144I, and R144S), now includes a fourth amino acid change, R144G. Similarly other positions with two or more changes include K123R and K123N, D158N and D158G, M230I and M230V.

I'm trying to back track, clicking on the links within the commentaries, and I'm not understanding. I understand M2301 which makes it easier to transmit. But that's about all.
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Ooops, I posted this in a rather dead thread. I have a friend who is from Egypt who (time permitting) can translate these reports very accurately. He is not in Egypt at this time, so he cannot give 'on the ground' news, but I'll send this thread to him to see what he has time to do.

Thanks for keeping up the good work while I was busy lurking, guys. :tiphat:

:applause: :applause:
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Welcome Lexecon and no worries.
New Thread started here......
 
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Re: EGYPT - "Bird flu still out of control" / 4904 suspected cases since 03/2006

Re: EGYPT - "Bird flu still out of control" / 4904 suspected cases since 03/2006

.......sibling of the latest case has been hospitalized.
 
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Re: Egypt Human Cases Feb 25th - Mar 7th 2008

Re: Egypt Human Cases Feb 25th - Mar 7th 2008

This thread is back open for business!!!
 
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Re: Egypt Human Cases Feb 25th - Mar 7th 2008

Re: Egypt Human Cases Feb 25th - Mar 7th 2008

http://www.kuna.net.kw/NewsAgenciesPublicSite/ArticleDetails.aspx?id=1890111&Language=en

<TABLE cellSpacing=0 cellPadding=0 width="100%" border=0><TBODY><TR><TD class=NewsDetailsTitle>Egypt reports 47th bird flu case </TD></TR><TR><TD></TD></TR><TR><TD class=NewsDetailsCategory>Health 3/9/2008 12:03:00 AM</TD></TR><TR><TD> </TD></TR><TR><TD class=ArticleDetails><TABLE class=ImageFloat cellSpacing=0 cellPadding=0 align=left><TBODY><TR><TD></TD></TR><TR><TD class=pictureCaption id=tdCaption align=middle width=180></TD></TR></TBODY></TABLE>CAIRO, March 8 (KUNA) -- An eight-year old boy tested positive for bird flu in Al-Fayyoum governorate, south Cairo, Saturday.
The boy has been admitted to hospital for suffering from high body temperature, difficult breathing and pneumonia, Spokesman of the Egyptian Ministry of Health and Population Abdulrahman Shahin.
The results of bird flu tests, that were conducted immediately, came positive, he disclosed.
The boy is being treated with Tamiflu in a bid to rescue his live.
The local veterinary authorities in Al-Fayyoum culled thousands of birds in the vicinity of the boy's house and kept his brother in quarantine under suspicion of being infected as well, he added.
This is the 47th bird flu case reported in Egypt since first outbreak of the fatal disease in February, 2006.
The disease claimed 20 lives in Egypt so far.
The Egyptian authorities are trying effortlessly to contain the disease through veterinary measures in parallel with media campaign.
Minister of Health and Population Hatem Al-Gebali instructed hospitals countrywide to be put on high alert for an suspected bird flu case and ordered the health officials to adopt preventive measures. (end) bna.gb KUNA 090003 Mar 08NNNN </TD></TR></TBODY></TABLE>
 
Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Egypt announces injury No. 47 avian influenza illness of a child of Fayoum 3/8/2008 5:42:00 PM

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</TD></TR><TR><TD class=phototitle align=middle height=18>الإصابة رقم 47 بمرض أنفلونزا الطيور
No. 47 infection disease avian influenza </TD></TR></TBODY></TABLE>

القاهرة - محرر مصراوي- أعلنت وزارة الصحة المصرية يوم السبت عن ظهور الإصابة البشرية رقم 47 بمرض أنفلونزا الطيور لطفل من عزبة "بريك قلمشاه" - مركز اطسا بمحافظة الفيوم ويدعى عبدالحميد السيد يوسف 8 سنوات.​
CAIRO - Editor TOM - The Ministry of Health in Egypt on Saturday as the emergence of human infection No. 47 avian influenza illness of a child of Ezbet "Brekke Klmhah" - Center Team Fayoum Governorate contends Mr. Abdul Hamid Youssef 8 years.

وقالت وكالة أنباء الشرق الأوسط نقلا عن الدكتور عبدالرحمن شاهين المستشار الاعلامى والمتحدث الرسمي لوزارة الصحة والسكان أن المريض كان قد دخل مستشفى حميات الفيوم وهو يعانى من ارتفاع في درجة الحرارة وضيق بالتنفس والتهاب رئوي عقب تعرضه لطيور نافقة مصابة بمرض أنفلونزا الطيور وتم إعطائه عقار "التاميفلو" فور الاشتباه في إصابته بالمرض ثم تم تحويله يوم السبت إلى مستشفى منشية البكري.​
The Middle East News Agency quoted Dr. Abdulrahman Shaheen Media adviser and official spokesman for the Ministry of Health and Population that the patient had entered hospital salt Fayoum He suffers from high temperature and narrow breathing and pneumonia after being infected dead birds contracted avian influenza were given drug "Tamiflu ®" Once he suspected the disease was then transferred to a hospital on Saturday Adviser Bakry.

وكانت أربع نساء مصريات قد لقين حتفهن بسبب إنفلونزا الطيور في ديسمبر 2007 ليرتفع إلى 19 عدد الذين ماتوا هناك جراء الإصابة بهذا المرض منذ أوائل عام 2006.​
The four women have married died because of avian influenza in December 2007 to increase to 19 the number who died there by the disease since early 2006.

يشار إلى أن إجمالي ضحايا أنفلونزا الطيور يزيد عن 230 شخصا في أنحاء العالم منذ عام 2003, حيث وردت تقارير عن ظهوره في عدة دول أفريقية وآسيوية.​
It should be noted that the total victims of bird flu more than 230 people around the world since 2003, when there were reports of his appearance in several African and Asian countries.

ويخشى الخبراء من تحور الفيروس ليصبح قادرا على الانتقال بسهولة بين البشر، مما يهدد بوباء قد يودي بحياة الملايين في أنحاء متفرقة من العالم.​
Experts fear the virus to alter be able to move easily between humans, threatening epidemic had kills millions in the four corners of the world.

 
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Re: Egypt Human Cases Feb 25th +

Re: Egypt Human Cases Feb 25th +

Commentary http://www.recombinomics.com/feed.xml http://www.newsnow.co.uk/nn/Recombinomics

New Suspect H5N1 Cluster in Fayoum Egypt

Recombinomics Commentary 22:36
March 8, 2008

The boy has been admitted to hospital for suffering from high body temperature, difficult breathing and pneumonia, Spokesman of the Egyptian Ministry of Health and Population Abdulrahman Shahin.
The results of bird flu tests, that were conducted immediately, came positive, he disclosed.

The boy is being treated with Tamiflu in a bid to rescue his live.
The local veterinary authorities in Al-Fayyoum culled thousands of birds in the vicinity of the boy's house and kept his brother in quarantine under suspicion of being infected as well

The above comments describe another suspect cluster in Fayoum. The index case has developed pneumonia, like all previous confirmed cases this year, in marked contrast to last season. This is the second suspect cluster in Fayoum in less than a week, and raise concerns that the added complexity of H5N1 in Egypt is leading toward more efficient transmission to humans.

Release of sequences on these cases as well as those cases at the end of 2007 would be useful.



.
 
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