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China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

China says 19-year-old woman dies from bird flu - Yahoo! News

China says 19-year-old woman dies from bird flu

By GILLIAN WONG, Associated Press Writer Gillian Wong, Associated Press Writer
BEIJING ?

A Chinese woman has died from bird flu in a Beijing hospital, the government reported Tuesday, but the World Health Organization said the case did not appear to signal a new public health threat.


China's Ministry of Health said Huang Yanqing, 19, died Monday and tests confirmed she had the H5N1 bird flu virus. The official Xinhua News Agency said Huang became ill after buying and cleaning nine ducks in December at a market in Hebei province, which borders Beijing.

It was the first reported death in China from the illness in nearly a year.Her father, Huang Jinxian, told reporters that the family tried to treat Yanqing at home first with store bought medicine.

"It was useless, so we sent her to Guanzhuang hospital" in the eastern suburbs of Beijing, he said.

The WHO said Huang's case was similar to others reported worldwide, in that it did not appear to involve human-to-human transmission.

"This single case, which appears to have occurred during the slaughtering and preparation of poultry, does not change our risk assessment," the organization's Beijing office said in a statement.

Officials worry the virus could mutate into a much-feared form that could spread easily among people. But, for now, it remains hard for people to catch, with most human cases linked to contact with infected birds.

According to the latest WHO tally, bird flu has killed 248 people worldwide since 2003, including 21 in China.

In northern Vietnam, meanwhile, an 8-year-old girl has tested positive for the disease ? the first human case reported there in almost a year, health officials said Tuesday.

The girl from Thanh Hoa province was admitted to a hospital on Dec. 27 with a high fever and other symptoms after eating a sick goose raised by the family, said Nguyen Ngoc Thanh, acting director of the provincial health department. The girl is recovering.

The H5N1 bird flu virus continues to devastate poultry stocks around the world. China, which raises more poultry than any other country, has vowed to aggressively fight the virus.
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<cite cite="http://news.yahoo.com/s/ap/20090106/ap_on_re_as/as_china_bird_flu">China says 19-year-old woman dies from bird flu - Yahoo! News</cite>
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Emergency meeting, I wonder what the emergency is, can't be 1 confirmed case ? Could be anything, including handling the publicity.

An emergency meeting was convened yesterday in Beijing to handle the bird-flu case, Xinhua said without elaborating.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Emergency meeting, I wonder what the emergency is, can't be 1 confirmed case ?

Evidently, the fear is about the more than hundred of people involved, mostly health care workers that had contacts with deceased patient.

Tracing poultry movement is also an urgent task, because the market is said to be remained open until tuesday and the ducks have been sold well beyond the onset date of the patient firstly has bought infected animals.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

From post no. 19:

China's official Xinhua News Agency earlier reported that the woman from eastern Fujian province had bought nine ducks at a market in Hebei province, which surrounds Beijing, and then gutted the birds.

She gave three ducks to her father, uncle and a friend and kept the other six ducks, the agency reported.

It added that 116 people, including the patient's 14 family members and neighbour and 102 medical workers, had been in close contact with the patient.

A total of 13 people consumed the ducks bought by the victim, but she was the only one who fell ill, Xinhua said.

The market was open for business on Tuesday night and ducks were still being sold there, it said.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Emergency meeting, I wonder what the emergency is, can't be 1 confirmed case ? Could be anything, including handling the publicity.
The emergency is clade 7.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Time published: 06 January 2009 2315 hrs (SST) 1515 hrs (GMT)
最后更新:06 January 2009 2317 hrs (SST) 1517 hrs (GMT) Last Update: 06 January 2009 2317 hrs (SST) 1517 hrs (GMT)

曾清洗鸭子内脏女子染禽流感病逝

Cleaning woman had been infected duck offal died of bird flu

[亚洲新闻网] 沉寂一时的禽流感病毒又再肆虐。

[Asia News Network] silence the moment the bird flu virus raging again. 中国北京一名少女证实感染了禽流感而死亡。

Beijing, China confirmed a teenage girl was infected with bird flu.

越南也有一名八岁女童被发现染上禽流感,她在入院前曾经接触过家禽。 Vietnam also has an eight-year-old girl was found infected with bird flu, she had been in pre-hospital exposure to poultry. 卫生人员也从她住家附近的家禽身上,验出H5N1病毒。 Health personnel from her home near the body of poultry, tested H5N1.

病逝的19岁少女黄燕清,住在北京朝阳区的一个村子里。

The 19-year-old girl died Huang Yan-qing, living in Chaoyang District, Beijing, in a village.

她在两个多星期前出现肺炎等禽流感症状而入院治疗,星期一不治身亡。

She more than two weeks before the emergence of bird flu symptoms such as pneumonia and were admitted into hospital on Monday died.

死者患病前曾经在河北省买回几只当场宰杀的鸭子,并清洗过鸭子内脏。

The deceased had been sick before in Hebei Province on the spot to buy a few ducks slaughtered and cleaned duck offal.

死者父亲表示,?19日(买鸭)回来, 20日吃了,吃了(鸭子) ,大概24日开始发烧。在家里买感冒药,退烧药吃了两天不怎么管用,后来就去了管庄医院。?

The deceased father said, "on the 19th (buy duck) back on the 20th to eat, and eat it (duck), probably the beginning of a fever on the 24th.

At home to buy cold medicine, anti-fever for two days药吃less effective, and later went Pipe Zhuang hospital. "

这是中国将近一年来的首起人类禽流感死亡事件。

This is almost a year to China's first human bird flu deaths.

北京市政府已经派遣卫生人员,为死者居住的村子全面消毒,同时密切留意同死者接触过的100多人的健康状况。

Beijing Municipal Government has been sending health personnel, for the deceased, a resident of the village comprehensive disinfection, at the same time keep a close watch on the deceased have been in contact with more than 100 health.

当局也相继向世界卫生组织以及港澳地区通报了相关信息。

Authorities also have to inform the World Health Organization, and Hong Kong and Macao regions of the relevant information. 中国已经有至少20人死于禽流感。 China has at least 20 people have died of bird flu.


http://www.cnachinese.com/stories/asiapacific/view/67692/1/gb/.html
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

19-year-old woman in Beijing dies of avian flu
Created: 2009-1-7 1:26:06


A 19-YEAR-OLD Beijing woman who suffered the city's first human case of bird flu since 2003 has died, municipal health authorities said yesterday.

There were no immediate reports of any other illnesses associated with her death or outbreaks of bird flu among flocks in the region.

Huang Yanqing, who became sick on December 24, was hospitalized on December 27 as her condition deteriorated. She died on Monday morning.

Experts at the Beijing Center for Disease Control and Preventive Medical Research and the Academy of Military Medical Sciences checked biological samples taken from Huang.

The samples tested positive for the deadly H5N1 strain of bird flu, and the results were confirmed by the Ministry of Health.

Huang, a native of east China's Fujian Province who lived in Beijing, bought nine ducks on December 19 at the Yanjiaoqingong Market in Langfang City in Hebei Province.

Huang removed the ducks' internal organs, according to the Beijing Health Bureau, and gave ducks to her father, uncle and a friend and kept the other six ducks.

"According to the initial investigation, 13 people ate the ducks, and Huang was the only one who fell ill," said Zhao Qingchao, a Langfang government official.

"We thoroughly combed all stands in the market," he added.

The official said the ducks were traced to Jixian County in Tianjin City, which borders Beijing.

As of last evening, the Yanjiaoqingong Market was still open for business, and ducks were still being sold there.

No bird flu cases have been found in Langfang City so far, a spokesperson for the Ministry of Agriculture said yesterday.

Experts at the ministry, the Chinese Center for Disease Control and Prevention and the Beijing Center for Disease Control and Preventive Medical Research have arrived in Langfang to complete the investigation.

The Beijing Health Bureau said 116 people, including Huang's 14 family members and neighbors and 102 medical workers, had been in close contact with the patient. Among them, one nurse suffered a fever but has recovered.

Beijing reported the case to the World Health Organization and health authorities in the Hong Kong and Macau special administrative regions.

An emergency meeting was convened in Beijing on Monday evening to address the bird flu case.

Beijing has carried out a series of bird flu prevention and control measures, including disinfecting and isolating Huang's house and the wards where she was treated.

Medical institutions at all levels are closely monitoring for possible additional cases, according to local officials.

Last month, a baby girl was diagnosed as having the less-virulent H9N2 bird flu strain and received treatment in a Hong Kong hospital.






Xinhua

http://www.shanghaidaily.com/article/print.asp?id=387212
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Emergency meeting, I wonder what the emergency is, can't be 1 confirmed case ? Could be anything, including handling the publicity.
From Jiangsu outbreak:

http://www.oie.int/wahis/public.php?page=single_report&pop=1&reportid=7636
Gene sequencing by the National Avian Influenza Reference Laboratory indicated that this virus is very similar to the avian influenza virus variant isolated in Shanxi in 2006.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Source: http://www.thestandard.com.hk/news_detail.asp?pp_cat=13&art_id=76699&sid=22135614&con_type=1

Bird flu fears return after death in Beijing

Patsy Moy and Agence France-Presse

Wednesday, January 07, 2009

A 19-year-old Beijing woman has died of avian flu, reigniting fears of bird flu transmission to humans.

It is the first reported death from the disease in the mainland for nearly a year.

Chinese University microbiologist Paul Chan Kay-sheung said yesterday that, as long as the virus continues to circulate in poultry, the threat of transmission to humans remains.

"There is no sign avian flu is weakening. So we expect to see more humans getting the virus from birds," Chan said.

He also warned that, once human-to-human transmissions were detected, the world could face a pandemic.

Chan said global statistics indicate the death rate of bird flu in humans is 60 percent, which is "very high" when compared with one in a thousand in normal human flu.



He said the large human traffic between Hong Kong and the mainland increases the risk of transmission. But he stopped short of saying Hong Kong should stockpile the new H5 vaccines.

Confirmation of the H5N1 death in Beijing was received by the Department of Health's Centre for Health Protection yesterday.

A CHP spokesman said the victim was a 19-year- old woman who lived in a Beijing suburb.

She developed symptoms on December 24 and died on January 5.

According to the Xinhua News Agency, the woman, Huang Yanqing, died on Monday after buying nine ducks at a market in Beijing's neighboring Hebei province.


The bureau said 116 people had been in close contact with Huang.

One of them, a nurse, had contracted a fever but recovered.

In Vietnam, authorities reported an eight-year- old girl has tested positive for H5N1 in the north of the country.

The girl contracted pneumonia in Thanh Hoa province on December 27 after eating poultry and was admitted to a provincial hospital on January 2, local officials said.

She is recovering well, they added.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Woman thought to have bird flu dies



Published: Jan. 6, 2009 at 2:27 PM


Order reprints | Feedback
<STYLE itxtvisited="1"> .content_embed { float: right; padding: 8px; width: 280px; margin: 0 0 8px 8px; border: 1px solid #ccc; background: #fff; } .photo_embed { float: right; width: 301px; margin: 0 0 8px 8px; background: #fff; } .video_embed { float: right; width: 301px; margin: 0 0 8px 8px; background: #fff; }</STYLE>BEIJING, Jan. 6 (UPI) -- A woman suspected of having contracted bird flu has died, local health officials in Beijing said Tuesday.
Zhao Qingchao, an official with Langfang municipal government, said Huang Yanqing apparently was the only one of 13 people who ate the duck to become fatally ill, the state-run news agency Xinhua reported Tuesday.
Huang bought nine ducks at the Yanjiaoqingong Market in Langfang City of Beijing's neighboring Hebei Province Dec. 19, then cleaned the ducks' internal organs before giving three ducks to other people, the Beijing Municipal Health Bureau said.
"According to the initial investigation, a total of 13 people have eaten the duck and Huang is the only one who fell ill," Zhao said. "We had thoroughly combed all stands in the market."
He said the ducks' origin was traced to Jixian County in Tianjin Municipality.
No bird flu case had been found in Langfang City so far, a spokesperson with China's Ministry of Agriculture told Xinhua.
The Beijing Municipal Health Bureau said 116 people were in close contact with the victim. One healthcare professional in contact with Huang contracted bird flu, but recovered, the bureau said.
Beijing officials reported the incident to the World Health Organization, as well as health authorities in Hong Kong and Macao. Official also have begun bird flu prevention and control measures.

http://www.upi.com/Science_News/2009/01/06/Woman_thought_to_have_bird_flu_dies/UPI-93701231270068/
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Commentary

http://www.recombinomics.com/News/01060903/H5N1_Beijing_7_Concerns.html
Clade 7 H5N1 In Beijing Raises Pandemic Concerns

Recombinomics Commentary 20:06
January 6, 2009

Gene sequencing by the National Avian Influenza Reference Laboratory indicated that this virus is very similar to the avian influenza virus variant isolated in Shanxi in 2006.

A 19-YEAR-OLD Beijing woman who suffered the city's first human case of bird flu since 2003 has died, municipal health authorities said yesterday.

The sequencing comments above are from the OIE report on the H5N1 from the Jiangsu outbreaks last month, followed by the most recent confirmed human case in China (see updated map), who died yesterday. The “virus variant” is clade 7, as seen in phylogenetic analysis of A/chicken Shangxi/02/2006 in the latest WHO on vaccine targets. On the same branch is A/Beijing/01/2003, which was isolated from the first H5N1 confirmed case in mainland China.

It is likely that the latest case was also infected by clade 7 H5N1, which is vaccine resistant because most vaccines target clade 1 or 2, which are significantly different than clade 7.

The details of the Jiangsu outbreaks are unclear. Some local media reports suggested the outbreak was large and involved dead poultry that was shipped to market. Other reports acknowledged the H5N1 infection, but noted that the infected birds were asymptomatic and identified through routine screening.

However, if the latest case was fatally infected by clade 7 from an asymptomatic duck, then the potential for additional cases is high because the virus can travel and dispress undetected. Moreover, since clade 7 is resistant to the most common vaccines, it could be widespread.

Clade 7 was also reported in Vietnam in August, and a clade 7 target was recently identified by the WHO. There currently is no clade 7 pandemic vaccine, and the selected target is only proposed as a target, as indicated in the most recent WHO vaccine update. The earlier presence of clade 7 in Vietnam may be related to the recent confirmed human case in northern Vietnam, which was announced today.

Thus, more detail about the H5N1 in Beijing and Vietnam, including sequence data from these isolates, as well as the WHO vaccine target, A/chicken/Vietnam/NCVD-016/2008, would be useful.

The presence of vaccine resistant H5N1 in asymptomatic ducks in Beijing would create significant pandemic concerns.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Can we assume that Hunang became infected as the result of a higher viral load from the process of cleaning the bird?

.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Can we assume that Hunang became infected as the result of a higher viral load from the process of cleaning the bird?

.
Cooking kills the virus, so those most at risk are those who handle the bird prior to cooking.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

<LI class="dateStamp first"><SMALL>JANUARY 7, 2009</SMALL> <!-- ID: SB123127188802458267 --><!-- TYPE: Health --><!-- DISPLAY-NAME: Health --><!-- PUBLICATION: The Wall Street Journal Interactive Edition --><!-- DATE: 2009-01-07 00:01 --><!-- COPYRIGHT: Dow Jones & Company, Inc. --><!-- ORIGINAL-ID: --><!-- article start --><!--CODE=SUBJECT SYMBOL=OWONCODE=SUBJECT SYMBOL=OASNCODE=STATISTIC SYMBOL=FREECODE=INDUSTRY SYMBOL=DHC-->Beijing Woman Dies of Avian Flu

Authorities on Alert After Beijing Death; More Bird Cases Seen

more in Health ?

<IFRAME id=ad0_0_WA_0001Ciframe style="PADDING-RIGHT: 0px; PADDING-LEFT: 0px; PADDING-BOTTOM: 0px; MARGIN: 0px; PADDING-TOP: 0px" border=0 marginWidth=0 marginHeight=0 src="http://ad.doubleclick.net/adi/bottom.interactive.wsj.com/lifestyle_health_story;!category=;msrc=;;mc=wsjfreezone;tile=3;sz=571x47;ord=2490249024902490;" frameBorder=0 width=571 scrolling=no height=47 undefined="margin:0px; padding:0px"></IFRAME>

By GORDON FAIRCLOUGH

SHANGHAI -- A 19-year-old Beijing woman has died of bird flu, the first human case of the virus in China since February last year, the government said Tuesday, putting public-health officials on higher alert for a possible resurgence of the disease this winter.
The woman, who lived on the outskirts of China's capital, succumbed Monday morning to the H5N1 strain of avian influenza, according to a statement by the Beijing health bureau. It didn't say how she became infected.
Mao Qun'an, the spokesman for the Ministry of Health, said public-health officials have forecast a likely increase in avian influenza among birds this year, raising the possibility of more human infections.
"We have been paying great attention" to the possibility of human illnesses, Mr. Mao said. But, he added, because bird flu isn't readily transmissible to people, there is "no need to get nervous."
Bird flu remains primarily a threat to poultry, not humans, but the World Health Organization and national public-health authorities remain on guard because the virus has the potential to mutate into a more contagious form and spark a pandemic.
Also on Tuesday, health officials in Vietnam said an 8-year-old girl had tested positive for the disease, the Associated Press reported. It was the first human case reported in that country in nearly a year.
Human infections with H5N1 peaked in 2006, when 115 cases -- 79 of them fatal -- were reported to the WHO. In 2008, there were 40 cases of human infection with H5N1, leading to 30 deaths -- a tiny number compared with the death toll from ordinary flu.
Since fall, outbreaks of avian influenza in birds have been reported in countries including Vietnam, Thailand, India, Togo and Germany. One person died of bird flu in Indonesia in November, and a teenager in Egypt died of the disease in December.


India Battles an Outbreak of Bird Flu

<SMALL>1:17</SMALL> Poultry farmers in India's eastern West Bengal state face ruin after fresh outbreak of bird flu. Worries that the flu virus could mutate and could cause a global pandemic. Courtesy Reuters.





Chinese health officials said they have stepped up monitoring and infection-control measures since the Beijing woman's diagnosis. People who had close contact with the woman have been placed under medical observation, but none have shown any sign of infection, officials said. An official in the village where the woman lived said disinfection teams had visited the area Monday.
The Ministry of Agriculture and local agriculture officials said they have received no reports of avian-flu outbreaks in poultry in or around Beijing. Last month, the authorities ordered the slaughter of more than 350,000 chickens after routine testing of eggs turned up signs of bird flu in an east-coast province, more than 1,000 kilometers from Beijing.
Nyka Alexander, a spokeswoman for the WHO in Beijing, said the Chinese government had informed the organization of Monday's death.
Authorities in Hong Kong -- where tens of thousands of chickens were culled in December after dead birds tested positive for H5N1 -- as well as in Macau and Taiwan also were alerted, China said.
<CITE class=tagline>?Kersten Zhang in Beijing contributed to this article.</CITE> Write to Gordon Fairclough at gordon.fairclough@wsj.com
<!-- article end -->


http://online.wsj.com/article/SB123127188802458267.html?mod=#printMode
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Cooking kills the virus, so those most at risk are those who handle the bird prior to cooking.

I had assumed she "gave the birds" as uncooked birds, but it could be either way, since she did the prep work either way.

IF the reports about the HCW infection are true, does that indicate poor biosecurity or better mammalian-adapted genetics?

.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

I had assumed she "gave the birds" as uncooked birds, but it could be either way, since she did the prep work either way.

IF the reports about the HCW infection are true, does that indicate poor biosecurity or better mammalian-adapted genetics?

.
One report said the victim cleaned all 9 birds.

H5N1 in a HCW is a major red flag. UPI said the HCW had bird flu. Several reports said the nurse had a fever. No report said she had a fever due to something other than bird flu.

Clade 7 has a LOT of RBD changes and some are in patients from Indonesia.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

We do not know with certainty that this is a Clade 7.
 
Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

We do not know with certainty that this is a Clade 7.
I don't think anyone knows with certainty for the latest human case, but the Jiangsu outbreak is clear, while Shangxi in 2006 and Beijing in 2003 are public.

For the latest case, the timing and location strongly point toward clade 7. I would be VERY surpised if this isn't a clade 7 case.
 
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