China: Man Dies; Infected Father "Improving"; More Suspects

Niko · Dec 9, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

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Dec. 9 (<st1:stockticker w:st="on">CNA</st1:stockticker> Taipei 9 Mar), "Sing Tao Daily" reported that China's Jiangsu Province People's Hospital, doctors said bird flu landing[FONT=&quot]姓男子[/FONT]relatives might unusual circumstances, the details to wait for the Provincial Health Department announced, but the Provincial Health Office denied that the relatives of patients developed symptoms. <o

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Reports said that the second piece of Jiangsu recently confirmed human bird flu cases, the patient is infected with the H5N1 avian flu before the man's father died, the name of Wei Lu, Nanjing, the second hospital isolation treatment, the situation is improving. Wei Lu 24-year-old son had been killed because of avian flu infection.
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Reports quoted director of the Jiangsu Provincial People's Hospital doctors Yin Kai-sheng pointed out that patients with friends and relatives may have unusual circumstances, such as to the details of the provincial health department announced. However Provincial Health Department director of the Office of Emergency LI Shao-Dong, denied Wei Lu's wife and son's girlfriend symptoms, in the observation that they are not abnormal.
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LI Shao-Dong said that at present not clear whether it was human cases of avian moving, because two of the father and son have been to the farm produce market ago, also used outside meals, the initial determination should not be a person to person.
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The newspaper pointed out that there was news that his son had access to Wei Lu of more than 60 health care workers also need to observe.
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Reports that H5N1 has familial aggregation of low tendency to spread, but not the same as human flu spread rapidly.
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In addition, the report quoted the WHO representative office in <st1:country-region w:st="on"><st1

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<st1:date ls="trans" month="12" day="9" year="2007" w:st="on">12/9/2007</st1:date> 10:26:07 AM <st1:date ls="trans" month="12" day="9" year="2007" w:st="on">12/9/2007</st1:date> 10:26:07 AM

http://64.233.179.104/translate_c?h...=http://epochtimes.com/gb/7/12/9/n1936057.htm

Sally Furniss · Dec 9, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

No human to human transmission of bird flu, officials say

OFFICIALS have confirmed that the bird flu virus that killed a man and infected his father in Jiangsu Province cannot spread from human to human, the Ministry of Health said today.

The cause for the two infections was still being investigated, as both had no contact with poultry before becoming ill.

A 24-year-old man, surnamed Lu, died of bird flu on December 3, China's 17th fatality from the disease. Before he developed symptoms, Lu was at home preparing for an exam and had no contact with infected or deceased fowl, Xinhua news agency reported earlier.

Doctors confirmed that Lu's father, 52, had the H5N1 virus four days after his son's death, creating crucial questions about how the two infections occurred.

The World Health Organization said it could not rule out the possibility of human-to-human infection.

Scientists fear the disease could mutate into a version that spreads from person to person, risking wider outbreaks or even a global pandemic.

http://www.shanghaidaily.com/sp/article/2007/200712/20071210/article_341113.htm

Giuseppe · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

niman said:
Center □□□2007.12.09 preventing and controlling birds and beasts flu Nanjing issues an order □□to live □Central News Agency Center Qi Jiang □province □fathers and sons infect the birds and beasts flu to direct □the epidemic situation to be panic, □□□, Nanjing □bureau □low □□principle event, but also □the wrist control epidemic situation, issues an order all domesticated fowls city □not to be able to remain lives □□the night, □□only has the following night □□to change □Leng??. Hong Kong "□Fang Ri?" □□, Nanjing many □courtyards □event all three □its, the Nanjing resident generally did not know explodes □the epidemic situation. □, the Nanjing □bureau yesterday did not issue an order all domesticated fowls city □prohibition to live □"□the night", will not be able to remain to the next day, otherwise □□□□, some small cities □is forbidden □to sell lives □. Among them, Huimin □□city □tube committee □□, □□instruction under yesterday afternoon □, whole city all food markets □all □□□□line. □□□woman last night then □□□fell 50 □to live □, □loses not slightly, because □Leng?? demand was not big. Jiang? is many Hong Kong travels □□□the travel □□, the port □aviation □□□goes to Nanjing passenger "health direction". Hong Kong many travel agencies all pointed out that, the travel □mostly not □to □□or □the village, □the guest □does not have □□meets □the birds and beasts □, but □the reminder □□attention □person □lives.
http://news.chinatimes.com/2007Cti/...Content/0,4526,110109+112007120900372,00.html

I submit a new version of this article:
1) [AVIAN INFLUENZA, POULTRY, HUMAN, CHINA, CLUSTERED CASES] Bird flu prevention Nanjing ordered culling of chickens [Automated translation, see also FluTrackers forum for other news and comments. - ms.]
CNA

China's Jiangsu Province, a father and son infected with the avian flu epidemic caused panic, according to reports, Nanjing.

Even though the authorities played down the incident, but also an iron fist to control the epidemic, ordered all poultry markets can not stay [to be slaughtered]overnight live chickens, chicken vendors can only ... slaughter of chickens to sell frozen chicken.

Hong Kong, "Oriental Daily News" reported that many hospitals in Nanjing are tight-lipped [reticent] about the incident, the public generally does not know the Nanjing outbreak of the epidemic.

However, the Nanjing authorities yesterday ordered all poultry markets to prohibit live chicken "overnight" and could not stay to the next day, otherwise they will be destroyed, some small markets are prohibited from selling live chickens.

The Eastbound market Huimin CMC said yesterday afternoon in the instructions issued, the city will be all the markets implementation.

Chicken traders will be her last night Provisional kill 50 chickens, the loss is not small, because the demand for frozen chicken little.

Jiangsu is a lot of Hong Kong tours popular tourist destination, Hong Kong Dragon Airlines will be sent to Nanjing to the passengers, "Health Guide." Many Hong Kong travel agencies have pointed out that most tours to the townships or rural areas would not, tourists will not have access to birds, but members will be reminded to observe good personal hygiene.
-
SOURCE (CHINATIMES)
-----
(from my blog post No. 1960, http://hygimia69.blogspot.com)

sharon sanders · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Benvenuto Ironorehopper.

Giuseppe · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Florida1 said:
Benvenuto Ironorehopper.

Mille grazie! Thank you for the welcome message.

Theresa42 · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Google-translated from Chinese:

Nanjing bird "suspect" Jiaohua chicken
Dec 10, 2007

On 7 Jiangsu was the second confirmed case of human bird flu patients had to verify the identity, the name of Lu Wei [the father]. It is understood that Lu Wei due to a celebration of his son 陆侃 obtain college, especially their love Eating of chicken to the Confucius Temple in Nanjing Food stores, eating one of Jiaohua not fully cooked chicken. The following day, 陆侃 began fever and was sent to the Jiangsu Provincial People's Hospital, the results died. An Min Chen Nanjing 9 Sep

Lu Wei [the father], served as the Nanjing Military Region, director of communications repair job, intermediate grade last year to retirement age. He is currently Nanjing infectious disease hospital for treatment, according to sources, Lu Wei was reported in critical condition, but after Jiangsu Province and the Nanjing Military Region with the full medical experts rescue, now out of danger, his condition has stabilized, and getting better.

Rescue experts full mobilization authority

The Mainland's Lu Wei treatment is clearly a high degree of attention, Jiangsu set up a special rescue team, the mobilization of the Jiangsu Provincial People's Hospital, Nanjing Gulou Hospital in Nanjing and the Nanjing Military Region General Hospital and a number of hospital respiratory and other related specialties is the clinical experience rich authoritative experts have repeatedly collective consultation, careful development of treatment programs. Medical experts have devoted every night meetings, analysis, discussion Lu Wei's condition, and the timely adjustment of treatment programs.

It has been revealed that the Ministry of Health in Beijing also sent medical experts made a special trip to consultation. According to sources, at present Lu Wei's condition has stabilized, but medical experts are not taken lightly, they are still waiting 24 hours a day in the rotation Lu Wei bed, and closely observe the condition, and take immediate measures to prevent there repeated illness.

According to their relatives disclosure, Lu Wei's son, named 陆侃, this year 24-year-old. Academic performance has not been good, but through the efforts, this year just to acquire the Nanjing University Adult Education College, a people that end very excited. To celebrate 陆侃 in the Billboard parents specifically with him and his girlfriend to join the downtown Nanjing Confucius Temple play, the four individuals in the catering shop Confucius Temple eating wrapped with a thick layer of mud outside the Jiaohua chicken.

Eating of chicken to celebrate his son was admitted to University

According to analysis, this may be precisely because of the parcel outside the chicken and thick mud caused not fully cooked chicken. Eating of chicken and the next day, 陆侃 began fever, body temperature rapidly increased. People in Jiangsu Province were sent to hospital for emergency treatment, the results died.

As for why the incidence is 陆侃 First, his relatives said 陆侃 girlfriend custody of the two pet dogs, because she is foreigners, Nanjing relevant provisions restricting the number of dogs. In order to avoid detection, she "evacuation" of a foster 陆侃 home. To Eating of chicken in the 20 days before 陆侃 was that the one small dogs, for the prevention of rabies, he was injecting rabies vaccine, in accordance with the regulations must play five needles at a time when he had four consecutive injection of rabies vaccine, body the immunity is at the lowest point.

Be sent to the hospital for emergency treatment, and not be treated as avian flu treatment, doctors had suspected he is suffering from the plague [or rabies?].

His son suddenly died, my parents were very sad. Eating of chicken after the sixth day, when the father of Lu Wei fever, there is no cure heart. The urged acquaintances or in the next, he was to go to the hospital treatment.

Their relatives said Lu Wei a special love Eating of chicken, refrigerator equipment are scrapping good chicken. Precisely for this reason, not acquaintances of suspected bird flu, the results Lu Wei went to the Infectious Diseases Hospital in Nanjing, the diagnosis of avian flu.

Eating of chicken and the incidence of four men and women were found to be well

Curiously, with the Eating of chicken to the four individuals, two men have incidence, and the two women have the slightest okay. It has been revealed that 陆侃 girlfriend eat particular, but something has not.

It is learned that Lu Wei Lee, and his wife is also not related symptoms, but she has been isolated observation. Her cell phone has been closed, and she could not contact the outside world.

Wife [mother] of hospital physicians for the brain

Lu Wei after admission, as a clear diagnosis, the doctor immediately gave him lose the avian influenza antibodies and B-type blood albumin, and other symptomatic, due to drugs, because of medical treatment and proper measures, so stable condition.

Lu Wei sudden disaster to a blow is obviously heavy. Originally This is a very happy family, Lu Wei Lee, the wife [mother of 1st victim] of Canada, was born in September 1955, Shanxi Yicheng, is the Nanjing Brain Hospital Physical Diagnosis by the Deputy Director, the Deputy Director of physicians.

http://www.takungpao.com/news/07/12/10/MW-834827.htm

Niko · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

<table wdith="730" border="0" cellpadding="0" cellspacing="0"> <tbody><tr><td width="160">
</td><td style="color: rgb(194, 224, 76); font-size: 35pt; font-weight: bold; font-family: Arial;" align="center" width="400"> news.gov.hk </td> <td width="160"> </td> </tr> <tr><td width="160"> </td><td class="theme_title" align="center" width="400">From Hong Kong's Information Services Department</td><td class="theme_title" align="right" width="160"> <script language="javascript">  </script>December 10, 2007 </td></tr></tbody></table>  <table id="Table3" border="0" cellpadding="0" cellspacing="0" height="100%" width="567"> <col width="430"><col width="17"><col width="120"> <tbody><tr> <td colspan="3" class="theme_title">

December 10, 2007

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</td> </tr> <tr> <td class="theme_small_title"> Health
</td> </tr> <tr> <td>

</td> </tr> <tr> <td class="theme_news_header"> Anti-bird flu measures bolstered </td> </tr> <tr> <td>

</td> </tr> <tr> <td align="left" valign="top"> <table id="Table5" border="0" bordercolor="red" cellpadding="3" cellspacing="0" width="155"><tbody><tr><td width="155">

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</td></tr> </tbody></table>
Avian influenza preventive and surveillance measures have been bolstered following the confirmation of two human bird flu cases in Jiangsu.

The Centre for Health Protection today reviewed the latest situation and is following up with the Ministry of Health to study the possible sources of infection and the mode of transmission.

Family clusters of H5 infections have been reported before in Indonesia and Vietnam. Direct transmission from an infected poultry source could still explain some of these cases, while inefficient human-to-human transmission due to close contact with an infected person cannot be ruled out.

The aviation and travel industries have been informed of the latest situation in Jiangsu. Health information leaflets will be distributed to travellers going to the province. For aircraft coming from there, health announcements will be made on board while leaflets are being distributed to travellers at sea and land immigration checkpoints.

Temperature screening for in-bound travellers at all immigration control points will continue. Travellers who are symptomatic and have a history of possible exposure to the bird flu virus will be referred to hospitals for checks.

Targeted surveillance
The centre is liaising with the Hospital Authority and private hospitals to form enhanced pneumonia surveillance for the H5 virus, targeting passengers arriving from Jiangsu with pneumonia signs. Doctors will be updated on the latest situation and reminded to report suspected cases.

Community education will be boosted during the winter. While surveillance and monitoring of local chicken farms and pet bird gardens will stay, livestock farmers have been reminded to report sick and dead birds for collection and laboratory examination and adhere strictly to enforcing farm biosecurity measures.

A four-week enhanced surveillance programme will be launched in public hospitals until January 7. They should report to the Hospital Authority all patients who have pneumonia of unidentified etiology and have travelled within seven days before the onset of symptoms to affected areas with confirmed human cases of avian flu in the past six months.

Queen Mary Hospital's laboratory and the Public Health Laboratory Centre will provide rapid testing for avian influenza. The programme will be reviewed in four weeks.

The public should stay vigilant against bird flu and strictly observe personal and environmental hygiene. For more prevention tips click here.
</td> </tr> <tr> <td>
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</td> </tr> </tbody></table> </td> </tr> </tbody></table>http://www.news.gov.hk/en/category/healthandcommunity/071210/html/071210en05007.htm

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Commentary at

http://www.recombinomics.com/News/12100701/H5N1_Transmission.html

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Avian influenza ? situation in China - update 5

9 December 2007
The Ministry of Health in China has reported a new case of human infection with the H5N1 avian influenza virus in Jiangsu Province. The case was confirmed by the national laboratory on 6 December.
The 52-year old male is the father of the 24-year old man who died from H5N1 infection on 2 December 2007. He is one of the close contacts placed under medical observation by national authorities. He developed symptoms on 3 December and was sent immediately to hospital for treatment.
Of the 27 cases confirmed to date in China, 17 have been fatal.

http://www.who.int/csr/don/2007_12_09/en/

sharon sanders · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

From Niman's Commentary above - a quote from WHO -

"...'We know that this strain that we have seen here in China, Vietnam, Indonesia and Thailand has a very limited capability for human-to-human transmission,' he told a news conference...."

Doesn't this statement conflict with Nidom who has said that there are 5 variants of H5N1 in Indonesia alone? Here is map that Theresa42 prepared from Nidom's comments.

http://www.flutrackers.com/forum/showpost.php?p=111002&postcount=7

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Florida1 said:
From Niman's Commentary above - a quote from WHO -

"...'We know that this strain that we have seen here in China, Vietnam, Indonesia and Thailand has a very limited capability for human-to-human transmission,' he told a news conference...."

Doesn't this statement conflict with Nidom who has said that there are 5 variants of H5N1 in Indonesia alone? Here is map that Theresa42 prepared from Nidom's comments.

http://www.flutrackers.com/forum/showpost.php?p=111002&postcount=7

His is calling all H5N1 clades as being the same strain.

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

AVIAN INFLUENZA, HUMAN (157): CHINA (JIANGSU)
*********************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: Mon 10 Dec 2007
Source: Singtaonet.com [in Chinese, trans. Rappt.DS, edited]
<http://www.singtaonet.com/society_focus/200712/t20071210_688120.html>

[The following report provides new information relating to the source
of the H5N1 virus responsible for the death on 2 Dec 2007 of a
24-year-old man in Jiangsu province and the concurrent illness of his
father, and explains the possible relevance of the dog-bite incident.
- Mod.CP]

To celebrate [the 24-year-old's] acceptance [to a school of continuing
education], his mother and father took him and his girlfriend to
Nanjing's most bustling Confucian temple for some fun. At the temple's
restaurant, the 4 of them ate Beggar's Chicken, which was surrounded
by thick mud on the outside. [Dan Silver, the translator, comments
that a 1990 article from the New York Times provides a useful
introduction to Beggar's Chicken:
<http://query.nytimes.com/gst/fullpage.html?res=9C0CEFD91638F93BA35757C0A966958260>.]

According to analyses, perhaps because the mud on the outside was too
thick the chicken inside was not thoroughly cooked. On the 2nd day
after eating the chicken, [the young man] began feeling feverish. His
body temperature rose quickly and he was taken for emergency treatment
to Jiangsu Provincial People's Hospital. In the end, he could not be
saved.

As to why [he] was 1st to fall ill, a relative revealed that his
girlfriend keeps 2 pet dogs. Because she is from another part of
China, Nanjing limits the number of dogs [she can keep]. To avoid
discovery, she sent one to be looked after by [her boyfriend]. 20 days
before eating chicken, he was bitten by this small dog. To prevent
rabies, he began vaccine shots. 5 injections are needed and at the
time [of his illness] he had already completed 4 shots. His body's
immunity was [therefore] at its lowest point. When [the man] was 1st
sent to the hospital, he was not treated for avian influenza. The
physicians suspected he might have contracted plague.

After their son's sudden death, his father and mother were devastated.
On the 6th day after eating chicken, when the father developed fever,
he did not have the heart to seek treatment. Only after others begged
him did he go to the hospital. A relative said that [his] family loves
to eat chicken and his refrigerator is full of butchered chicken.
Because of this, the relative began to wonder if it might be avian
influenza, so [the man] went to the Nanjing
Municipal Infectious Disease Hospital where the diagnosis of avian
influenza was made.

The odd thing is that although 4 people went to eat chicken [at the
temple], only the 2 men fell ill and the 2 women are well. Reports say
that [the] girlfriend ate a lot of chicken but is perfectly fine.
Sources say that [the 24-year-old's mother] also has no similar
symptoms but has been isolated for observation. Her cell phone is
turned off and there is no contact with the outside world.

--
Communicated by:
ProMED-mail Rapporteur Dan Silver

[This exposure of father and son to the same poultry product (and
possibly the storage of refrigerated chicken in the father's house)
identifies a potential common source of infection and virtually
negates the possibility of human-to-human transmission being
responsible for these 2 cases. - Mod.CP

The possible relevance of the dog-bite incident is that 4 rabies
vaccine shots might have adversely affected the patient's immune
system. The 2 women who also ate the chicken should be checked for
antibody in case of asymptomatic infection. Or perhaps the men ate the
legs and thighs and the women the breast, with different degrees of
undercooking and/or original virus titer? - Mod.JW]

[see also:
Avian influenza, human (156): China (Jiangsu) 20071208.3967
Avian influenza, human (155): China (Jiangsu) 20071207.3945
Avian influenza, human (154): China (Jiangsu) 20071205.3920
Avian influenza, human (153): China (Jiangsu) 20071202.3886
Avian influenza, human (90): China, WHO 20070604.1809
Avian influenza, human (85): China, WHO 20070530.1743
Avian influenza, human (84): China 20070527.1699
Avian influenza, human (62): China, Egypt, WHO 20070331.1103]
........................................cp/jw/mj/jw

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

niman said:
AVIAN INFLUENZA, HUMAN (157): CHINA (JIANGSU)
*********************************************
Communicated by:
ProMED-mail Rapporteur Dan Silver

[This exposure of father and son to the same poultry product (and
possibly the storage of refrigerated chicken in the father's house)
identifies a potential common source of infection and virtually
negates the possibility of human-to-human transmission being
responsible for these 2 cases. - Mod.CP

The possible relevance of the dog-bite incident is that 4 rabies
vaccine shots might have adversely affected the patient's immune
system. The 2 women who also ate the chicken should be checked for
antibody in case of asymptomatic infection. Or perhaps the men ate the
legs and thighs and the women the breast, with different degrees of
undercooking and/or original virus titer? - Mod.JW]

Although the tortured logic used to explain away clear H2H transmission is somewhat entertaining, the commentaries remain quite embarassing to the scientific community.

There is no data to indicate the chicken was H5N1 positive before or after cooking. Similarly, the "virtually negates" comment on the twsited ad hoc argument for the chicken speaks volumes.

Perhaps the women are aliens and H5N1 immune, and this is part of a plot by Martians to conquer the world, begnning in China.

Perhaps perhaps is not very scientific.

The dog bite / rabies shots / short incubation - 1 day / long incubation - 11 days / white meat / dark meat proof on common source will give the duck blood pudding yarns a run for their money.

sharon sanders · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

niman said:
His is calling all H5N1 clades as being the same strain.

It is misleading. The clades are quite different genetically (even if they are reportedly the same strain). The Indonesian strain(s)/clades (or whatever) are not publicly known, so how can they be compared to the rest of Southeast Asia?

Dark Horse · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Is this goofy story about the man, his father, his girfriend and her dogs going to be the last we hear of this case? What an elaborate story. Well, regardless of the story, I hope they can put out the fire. I don't expect truth from China, rather draconian methods to contain what the media over there keeps calling an epidemic. I assume the word in chinese for "epidemic" is similiar to "outbreak." Or, let's say I hope so.

Sally Furniss · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Ministry 'not optimistic' about bird flu prevention

 [FONT=Arial,Helvetica,sans-serif](Xinhua)
Updated: 2007-12-11 00:01[/FONT]

[FONT=Arial,Helvetica,sans-serif] The possibilities of regional bird flu outbreaks were "very high" in the winter and coming spring, said Vice Minister of Agriculture Yin Chengjie on Monday.
Yin said although the country had made major achievements in preventing the disease, his ministry still considered the situation was "not optimistic" as there had been cases of poultry infection with a "relatively large contaminated area".
Yin said the critical point was to improve the disease control in the country's southern areas.
He said the methods of poultry breeding, slaughter, delivery and processing needed radical changes, adding the prevention measures were not fully carried out in some regions.
He ordered local departments to step up immunization measures ahead of the Chinese Spring Festival in early February next year.
He urged authorities to intensify supervision over bird activities along the border and in water areas by increasing sample test numbers and examination frequencies.
He also required managers of live poultry markets in the southern regions continue to implement sterilization measures on a regular basis and "take compulsory measures" once the bird flu virus was spotted.
Bird flu, or avian influenza, is a contagious disease of animal origin caused by viruses that normally infect only birds and,less commonly, pigs.
China's health authorities said on Monday that no human-to-human transmission had been confirmed in the two human cases of bird flu involving a father and son in the Nanjing area.
The means of transmission in these cases was unknown.
The 52-year-old man, surnamed Lu, was a native of Nanjing, capital of Jiangsu. He developed fever and was hospitalized for lower lobe pneumonia on December 3, according to the Ministry of Health.
Lu's son was said to have no known contact with dead poultry and the Jiangsu Animal Husbandry and Veterinary Bureau said earlier last week that no bird flu epidemic had been discovered in the province.
The father was in stable condition and showing signs of improvement on Monday.
The latest cases bring the number of confirmed human infections of bird flu in China to 27 since 2003, with 17 deaths.
The World Health Organization has warned that the virus could mutate into a form that is highly infectious among humans and easily transmissible from person to person. Such a change could mark the start of a global outbreak.

http://www.chinadaily.com.cn/china/2007-12/11/content_6311044.htm

[/FONT]

AlaskaDenise · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

Even CIDRAP is picking up the amazing circumstance of the 1 infected chicken that just happened to be undercooked and just happened to be earten only by one family.......
CIDRAP - Reports suggest common source in family H5N1 cases

Dec 10, 2007 (CIDRAP News) ? Chinese officials said today that analysis of a virus sample from a 24-year-old man who died of H5N1 avian influenza shows no signs of a dangerous mutation, as some news reports said the man and his father, who is hospitalized with an H5N1 infection, both had eaten undercooked chicken.

Mao Qun'an, a spokesman for China's health ministry, told reporters today that though the son's sample showed no evidence of mutation, authorities could not rule out the possibility of human-to-human transmission, Reuters reported.

"The virus is still avian and has not undergone a mutation in its nature," Qun'an said at a press conference. He said the men could have been infected from the same source or separate sources, according to Reuters.

The 24-year-old man, from Nanjing in eastern China's Jiangsu province, died on Nov 27 from an H5N1 infection, according to a previous report from the World Health Organization (WHO). Six days later his father was hospitalized, and on Dec 6 China's national laboratory confirmed the man had an H5N1 infection, according to a WHO statement yesterday. The father is listed as China's 27th H5N1 case-patient.

News of the men's H5N1 infections raised suspicions of human-to-human transmission after media reports and the WHO said the son had no known exposure to sick birds.

However, Ta Kung Pao, a Hong Kong newspaper controlled by the mainland, reported today that both men had eaten undercooked chicken in Nanjing, the capital of Jiangsu, the Reuters report said. The claims came from unnamed sources.

More details on the men's alleged consumption of undercooked chicken were reported today by ProMED-mail, the Internet-based reporting system of the International Society for Infectious Diseases. The ProMED post consists of an English translation of a news article from Singtaonet.com, a newspaper based in Hong Kong.

The ProMED post says the father and his wife took their son and his girlfriend to a restaurant at a temple, where the four ate a dish called "beggar's chicken." According to a 1990 report on beggar's chicken from the New York Times, the chicken is stuffed with herbs, wrapped in lotus leaves, packed with "6 pounds of pond mud," and baked at low heat for several hours.

Two days after eating the chicken, the son became feverish and was hospitalized, the ProMED report said, adding that his father got sick 6 days after eating the meal. Relatives also said the father's refrigerator was full of butchered chicken. The report speculates that the son got sick first because his immune system was weakened because he recently had undergone a series of rabies shots after he was bitten by one of his girlfriend's dogs.

Hans Troedsson, a WHO representative in China, said reports of the men eating undercooked chicken have not been confirmed, Reuters reported today.

The father is recovering after treatment with oseltamivir at the onset of symptoms, Troedsson told the Associated Press (AP) today.

Eighty-two people who had contact with the father and son are being monitored, but none appear to have symptoms, he told the AP.

The two recent cases serve as a reminder that "the virus is circulating in the environment, (and) there is a risk that we will see these isolated cases," Troedsson said.

So far, there is no strong evidence of human-to-human transmission of the H5N1 virus, and the WHO has not received a request to help officials in Nanjing investigate, he told the AP. "We don't see that is an imminent risk that these cases would be the start of a pandemic," he said.

See also:
Dec 9 WHO statement

Dec 4 WHO statement

WHO H5N1 case count
Dec 10 ProMED post on Chinese H5N1 cases
Dec 7 CIDRAP News story "Father of Chinese H5N1 fatality has infection"

.

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

AVIAN INFLUENZA, HUMAN (158): CHINA (JIANGSU)
***********************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

[The following comments have been received in response to the
Moderators' comments to the ProMED-mail post: Avian influenza, human
(157): China (Jiangsu) 20071210.3978]

[1]
Date: Mon 10 Dec 2007
From: William Simpson <simpsowm@musc.edu>

Genetic susceptibility
--------------------------
In addition to the possibility of similar exposures, there is the
apparent genetically related susceptibility reported in other "family
clusters." As far as I'm aware, all persons in family clusters who
have died have been genetically related (mother-son, father-son,
etc.) and never related by marriage (husband-wife, etc).

--
Communicated by:
William M. Simpson, Jr., MD
Professor of Family Medicine
Medical University of SC
Medical Director, SC Agromedicine Program
Charleston, SC, USA
<simpsowm@musc.edu>

[An important omission on our part. - Mod.CP]

******
[2]
Date: Mon 10 Dec 2007
From: Dave Halvorson <halvo002@umn.edu>

Where is any evidence that any human anywhere has contracted
avian influenza by eating chicken? Even pasteurization temperatures
inactivate avian influenza virus, and that temperature is well below
what anyone would ever call "rare" chicken. Please don't perpetuate
myths.

--
Communicated by:
Dave Halvorson <halvo002@umn.edu>

[The thrust of the comment was to highlight the existence of possible
sources of contact with poultry contrary to previous denials. We
agree that there is no evidence for transmission of avian influenza
virus by *eating* cooked, undercooked or uncooked diseased poultry, but
there is not much evidence for the transmission of infectivity by any
specific route. Failure to transmit is the norm. - Mod.CP]

[Also, presumably the rabies treatment included immune globulin of some
sort, which might have contained influenza antibodies.- Mod.LM]

[see also:
Avian influenza, human (157): China (Jiangsu) 20071210.3978
Avian influenza, human (156): China (Jiangsu) 20071208.3967
Avian influenza, human (155): China (Jiangsu) 20071207.3945
Avian influenza, human (154): China (Jiangsu) 20071205.3920
Avian influenza, human (153): China (Jiangsu) 20071202.3886
Avian influenza, human (90): China, WHO 20070604.1809
Avian influenza, human (85): China, WHO 20070530.1743
Avian influenza, human (84): China 20070527.1699
Avian influenza, human (62): China, Egypt, WHO 20070331.1103]
.............................................cp/msp/jw

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

niman said:
AVIAN INFLUENZA, HUMAN (158): CHINA (JIANGSU)
***********************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

[The following comments have been received in response to the
Moderators' comments to the ProMED-mail post: Avian influenza, human
(157): China (Jiangsu) 20071210.3978]

[1]
Date: Mon 10 Dec 2007
From: William Simpson <simpsowm@musc.edu>

Genetic susceptibility
--------------------------
In addition to the possibility of similar exposures, there is the
apparent genetically related susceptibility reported in other "family
clusters." As far as I'm aware, all persons in family clusters who
have died have been genetically related (mother-son, father-son,
etc.) and never related by marriage (husband-wife, etc).

--
Communicated by:
William M. Simpson, Jr., MD
Professor of Family Medicine
Medical University of SC
Medical Director, SC Agromedicine Program
Charleston, SC, USA
<simpsowm@musc.edu>

[An important omission on our part. - Mod.CP]

The soap opera continues. Although the reader / contributor and commentator don't seem to know of the MANY H5N1 cluster members who are not blood relatives, the cases are confirmed, public, and well known to those knowledgeable about this subject.

HenryN · Dec 10, 2007

Re: China: Man Dies; Infected Father "Improving"; More Suspects

niman said:
AVIAN INFLUENZA, HUMAN (158): CHINA (JIANGSU)
***********************************************

[2]
Date: Mon 10 Dec 2007
From: Dave Halvorson <halvo002@umn.edu>

Where is any evidence that any human anywhere has contracted
avian influenza by eating chicken? Even pasteurization temperatures
inactivate avian influenza virus, and that temperature is well below
what anyone would ever call "rare" chicken. Please don't perpetuate
myths.

--
Communicated by:
Dave Halvorson <halvo002@umn.edu>

[The thrust of the comment was to highlight the existence of possible
sources of contact with poultry contrary to previous denials. We
agree that there is no evidence for transmission of avian influenza
virus by *eating* cooked, undercooked or uncooked diseased poultry, but
there is not much evidence for the transmission of infectivity by any
specific route. Failure to transmit is the norm. - Mod.CP]

[Also, presumably the rabies treatment included immune globulin of some
sort, which might have contained influenza antibodies.- Mod.LM]

The thrust of the moderator's comment was to once again display the abilty of the commentators to posted utter nonsense masquerading as rationale thought.

Now we have a "might" on what the immunoglobulin MIGHT have contained, which again MIGHT be part of the Martian plot noted earlier.

China: Man Dies; Infected Father "Improving"; More Suspects

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