SARS-CoV-2 neutralizing serum antibodies in cats: a serological investigation

[Treyfish]

New research by Shi Zhengli and others: Wuhan's cat population is infected with new coronavirus, which may be transmitted by humans
04-04 12:02


Current research generally believes that the new coronavirus may originate from bats. How the new coronavirus spreads from bats to humans also requires direct contact between humans and intermediate host animals. However, it is unclear which animals are intermediate hosts of the new coronavirus. Recently, some scientific research teams are starting from which daily animals are susceptible to the new coronavirus to answer these questions, which is also critical to the prevention and control of the epidemic.

On April 3, local time, the research team of the State Key Laboratory of Agricultural Microbiology at Huazhong Agricultural University and the Wuhan Institute of Virology, Chinese Academy of Sciences jointly published a new study on the preprint platform bioRxiv, "SARS-CoV-2 neutralizing serum antibodies in cats: a serological investigation ".

They found through cat serum survey: Serum ELISA detection of 102 cats collected after the outbreak of the new crown epidemic in Wuhan showed that serum from 15 cats (14.7%) was positive for the receptor binding domain (RBD) of the new crown virus.
Among the positive samples, 11 had New Corona virus neutralizing antibodies. Among them, 3 cats with new crown patients had the highest neutralizing titers, indicating that the high neutralizing titers may be due to the close contact between the cat and the new crown patients. To.



https://m.sohu.com/a/385457135_26061...6379169OEq3XIC

[sharon sanders]

SARS-CoV-2 neutralizing serum antibodies in cats: a serological investigation

Qiang Zhang, Huajun Zhang, Kun Huang, Yong Yang, X ianfeng Hui, Jindong Gao, Xinglin He, Chengfei Li, Wenxiao Gong, Yufei Zhang, Cheng Peng, Xiaoxiao G ao, Huanchun Chen, Zhong Zou, Zhengli Shi, Meilin Jin
doi: https://doi.org/10.1101/2020.04.01.021196
This article is a preprint and has not been certified by peer review [what does this mean?].

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Abstract


Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, and rapidly spread worldwide. Previous studies suggested cat could be a potential susceptible animal of SARS-CoV-2. Here, we investigated the infection of SARS-CoV-2 in cats by detecting specific serum antibodies. A cohort of serum samples were collected from cats in Wuhan, including 102 sampled after COVID-19 outbreak, and 39 prior to the outbreak. 15 of 102 (14.7%) cat sera collected after the outbreak were positive for the receptor binding domain (RBD) of SARS-CoV-2 by indirect enzyme linked immunosorbent assay (ELISA). Among the positive samples, 11 had SARS-CoV-2 neutralizing antibodies with a titer ranging from 1/20 to 1/1080. No serological cross-reactivity was detected between the SARS-CoV-2 and type I or II feline infectious peritonitis virus (FIPV). Our data demonstrates that SARS-CoV-2 has infected cat population in Wuhan during the outbreak.


https://www.biorxiv.org/content/10.1...04.01.021196v1