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Vaccine
. 2021 Aug 7;S0264-410X(21)00948-8.
doi: 10.1016/j.vaccine.2021.07.057. Online ahead of print.
Influenza vaccine acceptance and hesitancy among adults hospitalized with severe acute respiratory illnesses, United States 2019-2020
Kelsey L Lytle 1 , Sean P Collins 1 , Leora R Feldstein 2 , Adrienne H Baughman 1 , Samuel M Brown 3 , Jonathan D Casey 1 , Heidi L Erickson 4 , Matthew C Exline 5 , D Clark Files 6 , Kevin W Gibbs 6 , Adit A Ginde 7 , Michelle N Gong 8 , Carlos G Grijalva 1 , Akram Khan 9 , Christopher J Lindsell 1 , Ithan D Peltan 3 , Matthew E Prekker 4 , Todd W Rice 1 , Nathan I Shapiro 10 , Jay S Steingrub 11 , William B Stubblefield 1 , Mark W Tenforde 2 , Kelsey N Womack 1 , Manish M Patel 2 , Wesley H Self 12 , Influenza and Other Viruses in the Acutely Ill (IVY) Network
Affiliations
- PMID: 34376307
- DOI: 10.1016/j.vaccine.2021.07.057
Abstract
Introduction: Understanding patient factors associated with not being vaccinated is essential for successful implementation of influenza vaccination programs.
Methods: We enrolled adults hospitalized with severe acute respiratory illness at 10 United States (US) hospitals during the 2019-2020 influenza season. We interviewed patients to collect data about influenza vaccination, sociodemographic characteristics, and vaccine perceptions.
Results: Among 679 participants, 264 (38.9%) reported not receiving influenza vaccination. Among those not vaccinated, 135 (51.1%) reported choosing not to receive a vaccine because of perceived ineffectiveness (36.7%) or risk (14.4%) of influenza vaccination. Sociodemographic factors associated with not being vaccinated included no medical insurance (aOR = 6.42; 95% CI: 2.52-16.38) and being non-White or Hispanic (aOR = 1.54, 95% CI: 1.02-2.32).
Conclusions: Optimizing uptake of influenza vaccination in the US may be improved by educational programs regarding vaccine safety and effectiveness and enhancing vaccine access, particularly among non-White and Hispanic Americans and those without medical insurance.
Keywords: Influenza; Medical insurance; Vaccination; Vaccine acceptance; Vaccine hesitancy.