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Vaccine. 2019 Jun 8. pii: S0264-410X(19)30709-1. doi: 10.1016/j.vaccine.2019.05.072. [Epub ahead of print]
The relative effects of determinants on Chinese adults' decision for influenza vaccination choice: What is the effect of priming?
Liao Q1, Lam WWT2, Wong CKH3, Lam C4, Chen J5, Fielding R6.
Author information
Abstract
OBJECTIVES:
To assess the relative effects of altering different factors (attributes) related to adults' decision for influenza vaccination choice, and whether priming modifies these relative effects.
METHODS:
Chinese adults were randomly allocated to either a control condition (non-risk related video), or one of the three health risk-priming conditions (disease (influenza) risk video, intervention (vaccine) risk video, or non-specific (air pollution) risk video), each comprising ∼200 participants, prior to a discrete choice experiment survey. Mixed logit modelling estimated the relative effects of pre-determined attributes influencing vaccination choice.
RESULTS:
Across all four conditions, for determining vaccination choice, Vaccine Efficacy had a greater effect than social cues (community vaccination coverage rate (CVCR) and doctors' advice) but social cues can compensate for the effect of "uncertain" vaccine safety; influenza case-fatality ratio (CFR) became dominantly important among all included attributes when it reached 20%; vaccination preference increased when a CVCR changed incrementally from 5% to 60% but declined thereafter when the CVCR reached 80%. Compared with Control participants, a CVCR increased by 80% had a smaller effect for participants primed by intervention risk on vaccination choice, while the effect of influenza risk relative to vaccine risk increased following disease risk priming.
CONCLUSION:
While increasing confidence on vaccine efficacy is more important for influenza with less severe consequences, highlighting disease consequences becomes increasingly important when its CFR increases, for promoting vaccination uptake. For a new vaccine with uncertain safety, involving doctors and early vaccine takers to validate vaccine safety should be important. Brief exposure to influenza/vaccine risk didn't increase the effect of specific risk on vaccination choice but may change the relative weight of disease versus intervention risk when individuals make trade-off for vaccination decision. Free riding on herd immunity may increase when community vaccination coverage is high particularly following intervention risk priming.
Copyright ? 2019 Elsevier Ltd. All rights reserved.
KEYWORDS:
Influenza vaccination; Preference; Priming; Risk judgment
PMID: 31186189 DOI: 10.1016/j.vaccine.2019.05.072
The relative effects of determinants on Chinese adults' decision for influenza vaccination choice: What is the effect of priming?
Liao Q1, Lam WWT2, Wong CKH3, Lam C4, Chen J5, Fielding R6.
Author information
Abstract
OBJECTIVES:
To assess the relative effects of altering different factors (attributes) related to adults' decision for influenza vaccination choice, and whether priming modifies these relative effects.
METHODS:
Chinese adults were randomly allocated to either a control condition (non-risk related video), or one of the three health risk-priming conditions (disease (influenza) risk video, intervention (vaccine) risk video, or non-specific (air pollution) risk video), each comprising ∼200 participants, prior to a discrete choice experiment survey. Mixed logit modelling estimated the relative effects of pre-determined attributes influencing vaccination choice.
RESULTS:
Across all four conditions, for determining vaccination choice, Vaccine Efficacy had a greater effect than social cues (community vaccination coverage rate (CVCR) and doctors' advice) but social cues can compensate for the effect of "uncertain" vaccine safety; influenza case-fatality ratio (CFR) became dominantly important among all included attributes when it reached 20%; vaccination preference increased when a CVCR changed incrementally from 5% to 60% but declined thereafter when the CVCR reached 80%. Compared with Control participants, a CVCR increased by 80% had a smaller effect for participants primed by intervention risk on vaccination choice, while the effect of influenza risk relative to vaccine risk increased following disease risk priming.
CONCLUSION:
While increasing confidence on vaccine efficacy is more important for influenza with less severe consequences, highlighting disease consequences becomes increasingly important when its CFR increases, for promoting vaccination uptake. For a new vaccine with uncertain safety, involving doctors and early vaccine takers to validate vaccine safety should be important. Brief exposure to influenza/vaccine risk didn't increase the effect of specific risk on vaccination choice but may change the relative weight of disease versus intervention risk when individuals make trade-off for vaccination decision. Free riding on herd immunity may increase when community vaccination coverage is high particularly following intervention risk priming.
Copyright ? 2019 Elsevier Ltd. All rights reserved.
KEYWORDS:
Influenza vaccination; Preference; Priming; Risk judgment
PMID: 31186189 DOI: 10.1016/j.vaccine.2019.05.072