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Possible Triggering Effect of Influenza Vaccination on Psoriasis

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  • Possible Triggering Effect of Influenza Vaccination on Psoriasis

    J Immunol Res. 2015;2015:258430. doi: 10.1155/2015/258430. Epub 2015 Aug 25.
    Possible Triggering Effect of Influenza Vaccination on Psoriasis.

    Gunes AT1, Fetil E1, Akarsu S1, Ozbagcivan O1, Babayeva L1.
    Author information

    Abstract

    Psoriasis is a chronic, recurrent, immune-mediated inflammatory disease and it can be provoked or exacerbated by a variety of different environmental factors, particularly infections and drugs. In addition, a possible association between vaccination and the new onset and/or exacerbation of psoriasis has been reported by a number of different authors. The aim of this study is to investigate the effects of influenza vaccination on patients with psoriasis. Here, we report the findings from 43 patients suffering from psoriasis (clinical phenotypes as mixed guttate/plaque lesions, palmoplantar or scalp psoriasis) whose diseases had been triggered after influenza vaccination applied in the 2009-2010 season. The short time intervals between vaccination and psoriasis flares in our patients and the lack of other possible triggers suggest that influenza vaccinations may have provocative effects on psoriasis. However, further large and controlled studies need to be carried out to confirm this relationship.


    PMID: 26380315 [PubMed - in process]
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