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Vaccine adjuvants confer an advantage to the kinetics of activation of follicular dendritic cells that are sensitive to peripheral tissue's injury

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  • Vaccine adjuvants confer an advantage to the kinetics of activation of follicular dendritic cells that are sensitive to peripheral tissue's injury

    Scand J Immunol. 2015 May 22. doi: 10.1111/sji.12313. [Epub ahead of print]
    Vaccine adjuvants confer an advantage to the kinetics of activation of follicular dendritic cells that are sensitive to peripheral tissue's injury.

    Cantisani R1, Piccioli D1.
    Author information

    Abstract

    vaccine adjuvants are substances used to enhance the efficacy of vaccines because are able to increase the immune response to co-administered antigens[1, 2]. MF59 is a safe and effective adjuvant licensed for human influenza vaccine in the European countries[1, 3]. Its mechanism of action is not completely understood yet, but it has been demonstrated that MF59 induces inflammation at injection. This article is protected by copyright. All rights reserved.
    This article is protected by copyright. All rights reserved.


    PMID: 25997835 [PubMed - as supplied by publisher]
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