Announcement

Collapse
No announcement yet.

Predicting post-vaccination autoimmunity: Who might be at risk?

Collapse
X
  • Filter
  • Time
  • Show
Clear All
new posts

  • Predicting post-vaccination autoimmunity: Who might be at risk?

    Predicting post-vaccination autoimmunity: Who might be at risk?
    Alessandra Soriano,Gideon Nesher,Yehuda Shoenfeld
    Pharmacological Research; Elsevier; Available online 30 September 2014

    Abstract Vaccinations have been used as an essential tool in the fight against infectious diseases, and succeeded in improving public health. However, adverse effects, including autoimmune conditions may occur following vaccinations (autoimmune/inflammatory syndrome induced by adjuvants ASIA syndrome). It has been postulated that autoimmunity could be triggered or enhanced by the vaccine immunogen contents, as well as by adjuvants, which are used to increase the immune reaction to the immunogen. Fortunately, vaccination-related ASIA is uncommon. Yet, by defining individuals at risk we may further limit the number of individuals developing post-vaccination ASIA. In this perspective we defined four groups of individuals who might be susceptible to develop vaccination-induced ASIA: patients with prior post-vaccination autoimmune phenomena, patients with a medical history of autoimmunity, patients with a history of allergic reactions, and individuals who are prone to develop autoimmunity (having a family history of autoimmune diseases; asymptomatic carriers of autoantibodies; carrying certain genetic profiles, etc.).

    “‘i love myself.’ the quietest. simplest. most powerful. revolution ever.” ---- nayyirah waheed

    Avatar: Franz Marc, Liegender Hund im Schnee 1911 (My posts are not intended as advice or professional assessments of any kind.)
Working...
X