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Vaccine. Alphavirus replicon particle vaccines developed for use in humans induce high levels of antibodies to influenza virus hemagglutinin in swine: Proof of concept.
Vaccine. 2009 Oct 21. [Epub ahead of print]
Alphavirus replicon particle vaccines developed for use in humans induce high levels of antibodies to influenza virus hemagglutinin in swine: Proof of concept.
Erdman MM, Kamrud KI, Harris DL, Smith J. - Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 11 Kildee, Ames, IA 50011, United States.
A propagation-defective, single-cycle, alphavirus replicon particle (RP) system was used to produce two vaccines against human influenza virus A/Wyoming/03/2003 (H3N2). One vaccine was prepared from Venezeulan equine encephalitis virus (VEEV) strain 3014 and the other from VEEV strain TC-83. Both vaccines induced high antibody titers to the influenza hemagglutinin (HA) protein and illustrated the potential of using alphavirus RP influenza vaccines in swine.
PMID: 19853679 [PubMed - as supplied by publisher]
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Alphavirus replicon particle vaccines developed for use in humans induce high levels of antibodies to influenza virus hemagglutinin in swine: Proof of concept.
Erdman MM, Kamrud KI, Harris DL, Smith J. - Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 11 Kildee, Ames, IA 50011, United States.
A propagation-defective, single-cycle, alphavirus replicon particle (RP) system was used to produce two vaccines against human influenza virus A/Wyoming/03/2003 (H3N2). One vaccine was prepared from Venezeulan equine encephalitis virus (VEEV) strain 3014 and the other from VEEV strain TC-83. Both vaccines induced high antibody titers to the influenza hemagglutinin (HA) protein and illustrated the potential of using alphavirus RP influenza vaccines in swine.
PMID: 19853679 [PubMed - as supplied by publisher]
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