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Clin Microbiol Infect. 2014 Mar 22. doi: 10.1111/1469-0691.12625. [Epub ahead of print]
Factors associated with influenza vaccination among adult cancer patients: A case-control study.
Vinograd I1, Baslo R, Eliakim-Raz N, Farbman L, Taha A, Sakhnini A, Lador A, Stemmer SM, Gafter-Gvili A, Fraser D, Leibovici L, Paul M.
Author information
Abstract
Influenza vaccination is recommended for cancer patients, however adherence is low. We aimed to identify predicting factors for vaccination among cancer patients. We conducted a case-control analysis of a patient cohort in the 2010-2011 influenza season. We included adult cancer patients with solid malignancies undergoing chemotherapy and haematological patients with active disease. Patients who died between October-November 2010 (N=43) were excluded from analysis. Cases received the 2011 seasonal influenza vaccine and controls did not. Data were obtained from patients' records and validated through personal interviews. We collected socio-demographic information, data on the malignancy and co-morbidities and triggers for vaccination and non-vaccination. We performed bivariate and multivariable analyses, in which vaccination status was the dependent variable. Of 806 patients included in analysis, 387 (48%) were vaccinated. Variables associated with vaccination on bivariate analysis were older age, higher socio-economic status, lower crowding-index, marital status (widowed >married >singles), malignancy type (haematological >solid tumours) and time from diagnosis, low-risk malignancy, diabetes, past vaccination, country of birth (non-Russian origin) and physicians' recommendations. Predicting factors found to be independently associated with vaccination on multivariable analysis were past vaccinations, low-risk malignancy and country of birth. In the analysis conducted among interviewees (N=561), recommendations from the oncologist (OR=10.7 95% CI 5.4-21.2) and from the primary care physician (OR=3.35 95% CI 2.05-5.49) were strong predictors for vaccination. We conclude that "habitual vaccinees" continue influenza vaccinations when ill with cancer. Physicians' recommendations, especially the oncologist's, have a major influence on patients' compliance with influenza vaccination. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Chemotherapy, Influenza, Neoplasm, Vaccine, adherence
PMID:
24655107
[PubMed - as supplied by publisher]
Factors associated with influenza vaccination among adult cancer patients: A case-control study.
Vinograd I1, Baslo R, Eliakim-Raz N, Farbman L, Taha A, Sakhnini A, Lador A, Stemmer SM, Gafter-Gvili A, Fraser D, Leibovici L, Paul M.
Author information
Abstract
Influenza vaccination is recommended for cancer patients, however adherence is low. We aimed to identify predicting factors for vaccination among cancer patients. We conducted a case-control analysis of a patient cohort in the 2010-2011 influenza season. We included adult cancer patients with solid malignancies undergoing chemotherapy and haematological patients with active disease. Patients who died between October-November 2010 (N=43) were excluded from analysis. Cases received the 2011 seasonal influenza vaccine and controls did not. Data were obtained from patients' records and validated through personal interviews. We collected socio-demographic information, data on the malignancy and co-morbidities and triggers for vaccination and non-vaccination. We performed bivariate and multivariable analyses, in which vaccination status was the dependent variable. Of 806 patients included in analysis, 387 (48%) were vaccinated. Variables associated with vaccination on bivariate analysis were older age, higher socio-economic status, lower crowding-index, marital status (widowed >married >singles), malignancy type (haematological >solid tumours) and time from diagnosis, low-risk malignancy, diabetes, past vaccination, country of birth (non-Russian origin) and physicians' recommendations. Predicting factors found to be independently associated with vaccination on multivariable analysis were past vaccinations, low-risk malignancy and country of birth. In the analysis conducted among interviewees (N=561), recommendations from the oncologist (OR=10.7 95% CI 5.4-21.2) and from the primary care physician (OR=3.35 95% CI 2.05-5.49) were strong predictors for vaccination. We conclude that "habitual vaccinees" continue influenza vaccinations when ill with cancer. Physicians' recommendations, especially the oncologist's, have a major influence on patients' compliance with influenza vaccination. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Chemotherapy, Influenza, Neoplasm, Vaccine, adherence
PMID:
24655107
[PubMed - as supplied by publisher]
