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The determinants of 2009 pandemic A/H1N1 influenza vaccination: A systematic review

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  • The determinants of 2009 pandemic A/H1N1 influenza vaccination: A systematic review

    Vaccine
    In Press, Uncorrected Proof - Note to users
    doi:10.1016/j.vaccine.2011.12.089 | How to Cite or Link Using DOI
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    Review
    The determinants of 2009 pandemic A/H1N1 influenza vaccination: A systematic review

    Stephanie Briena, b, Jeffrey C. Kwongc, d, e, David L. Buckeridgea, b, f, Corresponding Author Contact Information, E-mail The Corresponding Author

    a Surveillance Lab, McGill Clinical and Health Informatics, McGill University, 1140 Pine Avenue West, Montreal, Canada H3A 1A3
    b Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, Canada H3A 1A2
    c Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Canada M4N 3M5
    d Department of Family and Community Medicine, University of Toronto, 500 University Ave, Toronto, Canada M5G 1V7
    e Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Canada, M5T 3M7
    f Agence de la sant? et des services sociaux de Montr?al, Direction de sant? publique, 1301 Sherbrooke Street East, Montreal, Canada H2L 1M3

    Received 27 September 2011; revised 16 December 2011; Accepted 19 December 2011. Available online 31 December 2011.
    Abstract
    Background

    Pandemic A/H1N1 influenza vaccine coverage varied widely across countries. To understand the factors influencing pandemic influenza vaccination and to guide the development of successful vaccination programs for future influenza pandemics, we identified and summarized studies examining the determinants of vaccination during the 2009 influenza pandemic.
    Methods

    We performed a systematic literature review using the PubMED electronic database from June 2009 to February 2011. We included studies examining an association between a possible predictive variable and actual receipt of the pandemic A/H1N1 influenza vaccine. We excluded studies examining intention or willingness to receive the vaccine.
    Results

    Twenty-seven studies were identified from twelve countries. Pandemic influenza vaccine coverage varied from 4.8% to 92%. Coverage varied by population sub-group, country, and assessment method used. Most studies used questionnaires to estimate vaccine coverage, however seven (26%) used a vaccination registry. Factors that positively influenced pandemic influenza vaccination were: male sex, younger age, higher education, being a doctor, being in a priority group for which vaccination was recommended, receiving a prior seasonal influenza vaccination, believing the vaccine to be safe and/or effective, and obtaining information from official medical sources.
    Conclusions

    Vaccine coverage during the pandemic varied widely across countries and population sub-groups. We identified some consistent determinants of this variation that can be targeted to increase vaccination during future influenza pandemics.
    Highlights

    ► Twenty-seven studies were identified from thirteen countries. ► Pandemic influenza vaccine coverage ranged from 4.8% to 92%. ► Coverage varied by population sub-group, country, and assessment method used. ► We identified socio-economic and demographic factors associated with vaccination.

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