Autoimmun Rev . Clinical phenotype of AAV, anti-GBM disease and double-positive patients after SARS-CoV-2 vaccination

[tetano]

Autoimmun Rev


. 2024 Mar 13:103521.
doi: 10.1016/j.autrev.2024.103521. Online ahead of print. Clinical phenotype of AAV, anti-GBM disease and double-positive patients after SARS-CoV-2 vaccination

Yisha Li ¹ , Jie Wang ¹ , Shuang Liang ¹ , Yan Zhang ¹ , Zhe Feng ¹ , Guangyan Cai ²



Affiliations

• PMID: 38490282
• DOI: 10.1016/j.autrev.2024.103521

Abstract

The number of anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV), anti-glomerular basement membrane (GBM) disease and double-positive patients (DPPs) following the coronavirus disease 2019 (COVID-19) vaccine reported in the literature is increasing, we reviewed the reported cases of AAV, anti-GBM disease and DPPs subsequent to COVID-19 vaccination, and compared the disparities in DPPs who received the COVID-19 vaccination and those who did not. we did not observe any differences in clinical phenotype of AAV, anti-GBM disease and DPPs before and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination.

Keywords: ANCA-associated vasculitis; Anti-GBM disease; COVID-19 vaccination; Double-positive patients (DPPs).