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Sci Rep . Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study

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  • Sci Rep . Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study

    Sci Rep


    . 2023 May 24;13(1):8360.
    doi: 10.1038/s41598-023-34340-3. Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study

    Sean D McCabe # 1 2 , E Adrianne Hammershaimb # 1 3 4 , David Cheng 1 , Andy Shi 1 2 , Derek Shyr 1 2 , Shuting Shen 1 2 , Lyndsey D Cole 5 , Jessica R Cataldi 5 6 , William Allen 1 7 , Ryan Probasco 1 , Ben Silbermann 1 , Feng Zhang 1 8 9 10 11 , Regan Marsh 12 13 14 , Mark A Travassos 15 16 17 , Xihong Lin 18 19 20 21



    AffiliationsAbstract

    SARS-CoV-2 vaccines are useful tools to combat the Coronavirus Disease 2019 (COVID-19) pandemic, but vaccine reluctance threatens these vaccines' effectiveness. To address COVID-19 vaccine reluctance and ensure equitable distribution, understanding the extent of and factors associated with vaccine acceptance and uptake is critical. We report the results of a large nationwide study in the US conducted December 2020-May 2021 of 36,711 users from COVID-19-focused smartphone-based app How We Feel on their willingness to receive a COVID-19 vaccine. We identified sociodemographic and behavioral factors that were associated with COVID-19 vaccine acceptance and uptake, and we found several vulnerable groups at increased risk of COVID-19 burden, morbidity, and mortality were more likely to be reluctant to accept a vaccine and had lower rates of vaccination. Our findings highlight specific populations in which targeted efforts to develop education and outreach programs are needed to overcome poor vaccine acceptance and improve equitable access, diversity, and inclusion in the national response to COVID-19.


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