Announcement

Collapse
No announcement yet.

Cureus . Evaluation of the Effect of COVID-19 Vaccination on Exacerbations of Chronic Obstructive Pulmonary Disease: A Single-Center Study

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Cureus . Evaluation of the Effect of COVID-19 Vaccination on Exacerbations of Chronic Obstructive Pulmonary Disease: A Single-Center Study


    Cureus


    . 2022 Dec 20;14(12):e32751.
    doi: 10.7759/cureus.32751. eCollection 2022 Dec.
    Evaluation of the Effect of COVID-19 Vaccination on Exacerbations of Chronic Obstructive Pulmonary Disease: A Single-Center Study


    Tugce Sahin Ozdemirel 1 , Esma Zenbilli 2 , Kerem Ensarioglu 2 , Derya Hosgun 3 , Busra Balkay Babaev 2 , Melike Ak Ayaroglu 2 , Caglar Ertugrul 2 , Berna Akıncı Özyürek 4



    Affiliations

    Abstract

    Background and aim: Vaccinations have been one of the main approaches to reducing mortality and exacerbations caused by infectious agents in chronic obstructive pulmonary disease (COPD). Among viral pathogens, coronaviruses have been described to play a role. This study aims to investigate the role of coronavirus disease 2019 (COVID-19) vaccination on exacerbation reduction in patients with COPD.
    Methods: Patients diagnosed with COPD prior to the study date were considered the study population. Exacerbations of COPD before and after the COVID-19 vaccination were recorded. Patients with influenza and/or pneumococcal vaccination were excluded from the study due to their known role in reducing exacerbations of COPD.
    Results: The study included 152 patients with a mean age of 67.5 ± 9.7 years. Most patients were classified under Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages 2 and 3. In fully vaccinated patients, COPD exacerbation was observed to be higher than in those without full vaccination (70.5% vs. 55.3%, respectively). Total risk status and vaccination status, however, were seen to be in a positive correlation, with higher risk and complete vaccination status presenting with a higher count of COPD exacerbation.
    Conclusion: Although it is known that the administration of COVID-19 vaccines in patients in risk groups reduces the risk of disease, there is no study showing a positive effect on COPD exacerbations alone. In our study, it was observed that only the COVID-19 vaccine was ineffective in attacks without influenza and pneumococcal vaccines.

    Keywords: chronic obstructive pulmonary disease; copd; coronavirus disease 2019; covid-19; exacerbation; influenza; pneumococcal vaccine; vaccines.

Working...
X