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Open Forum Infect Dis . Risk of Long COVID in People Infected With Severe Acute Respiratory Syndrome Coronavirus 2 After 2 Doses of a Coronavirus Disease 2019 Vaccine: Community-Based, Matched Cohort Study

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  • Open Forum Infect Dis . Risk of Long COVID in People Infected With Severe Acute Respiratory Syndrome Coronavirus 2 After 2 Doses of a Coronavirus Disease 2019 Vaccine: Community-Based, Matched Cohort Study


    Open Forum Infect Dis


    . 2022 Sep 12;9(9):ofac464.
    doi: 10.1093/ofid/ofac464. eCollection 2022 Sep.
    Risk of Long COVID in People Infected With Severe Acute Respiratory Syndrome Coronavirus 2 After 2 Doses of a Coronavirus Disease 2019 Vaccine: Community-Based, Matched Cohort Study


    Daniel Ayoubkhani 1 2 , Matthew L Bosworth 1 , Sasha King 3 , Koen B Pouwels 4 5 , Myer Glickman 1 , Vahé Nafilyan 1 6 , Francesco Zaccardi 2 , Kamlesh Khunti 2 , Nisreen A Alwan 7 8 9 , A Sarah Walker 4 10



    Affiliations

    Abstract

    We investigated long COVID incidence by vaccination status in a random sample of UK adults from April 2020 to November 2021. Persistent symptoms were reported by 9.5% of 3090 breakthrough severe acute respiratory syndrome coronavirus 2 infections and 14.6% of unvaccinated controls (adjusted odds ratio, 0.59 [95% confidence interval, .50-.69]), emphasizing the need for public health initiatives to increase population-level vaccine uptake.

    Keywords: COVID-19; coronavirus; long COVID; post-COVID condition; vaccination.

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