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Am J Perinatol . Sinopharm COVID-19 Vaccination during Pregnancy Triggers Thyroid Stimulating Hormone Levels in Newborns

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  • Am J Perinatol . Sinopharm COVID-19 Vaccination during Pregnancy Triggers Thyroid Stimulating Hormone Levels in Newborns

    Am J Perinatol


    . 2025 Mar 6.
    doi: 10.1055/a-2526-5326. Online ahead of print. Sinopharm COVID-19 Vaccination during Pregnancy Triggers Thyroid Stimulating Hormone Levels in Newborns

    Aylar Vatanparast 1 , Faeze Daghigh 2 , Hossein Akbari 3



    AffiliationsAbstract

    The effects of covid vaccination on the fetus and placenta make pregnant women a special group in the vaccination series. Coronavirus vaccines are associated with endocrine complications such as thyroid disease.The study included pregnant women who received the corona virus disease 2019 (COVID-19) vaccine. Pregnant women were divided into three study groups; group A (who have not received the COVID-19 vaccine), group B (who received the Sinopharm vaccine during pregnancy), and group C (who received the Sinopharm vaccine before pregnancy). Blood samples were taken to measure thyroid stimulating hormone (TSH) levels in infants 3 to 5 days old. Neonatal TSH values below 5 mU/L are considered normal.Sinopharm/BBIBP-CorV during and/or before pregnancy was associated with a slight increase in mean TSH in newborns.Vaccination with Sinopharm/BBIBP-CorV during or before pregnancy may slightly increase neonatal TSH levels, but this is not clinically significant. · COVID-19 vaccines linked to endocrine disruption.. · Sinopharm CorV during pregnancy triggers TSH in infants.. · Sinopharm vaccination in pregnancy increases neonatal TSH levels..


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