Cureus . Bradycardia Related to Remdesivir During COVID-19: Persistent or Permanent? - FluTrackers News and Information

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Cureus . Bradycardia Related to Remdesivir During COVID-19: Persistent or Permanent?

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tetano

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Join Date: Dec 2009

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Cureus . Bradycardia Related to Remdesivir During COVID-19: Persistent or Permanent?

December 28, 2021, 05:39 AM

Cureus

. 2021 Nov 26;13(11):e19919.
doi: 10.7759/cureus.19919. eCollection 2021 Nov.
Bradycardia Related to Remdesivir During COVID-19: Persistent or Permanent?

Mani Maheshwari¹, Hemanthkumar Athiraman¹

Affiliations
PMID: 34956798

PMCID: PMC8675592

DOI: 10.7759/cureus.19919

Abstract

Remdesivir is an antiviral that inhibits RNA-dependent RNA polymerases of coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is a cornerstone of therapy for hospitalized patients with coronavirus disease 2019 (COVID-19), especially those worsening from a respiratory standpoint despite being started on antibiotics, dexamethasone, zinc, and vitamin C. This is a case report describing two COVID-19-positive patients with bradycardia after starting remdesivir. Once remdesivir was discontinued, one patient corrected to normal sinus rhythm, and the other continued with persistent bradycardia.

Keywords: adult hospital medicine; arrythymia; covid-19; drug induced bradycardia; remdesivir.

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