J Med Virol . Remdesivir might induce changes in electrocardiogram beyond bradycardia in patients with Coronavirus disease 2019 (COVID-19) - the pilot study

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J Med Virol


. 2021 Jul 7.
doi: 10.1002/jmv.27177. Online ahead of print.
Remdesivir might induce changes in electrocardiogram beyond bradycardia in patients with Coronavirus disease 2019 (COVID-19) - the pilot study


Petra Bistrovic ^{1 2} , Marko Lucijanic ^{2 3 4}



Affiliations

• PMID: 34232520
• DOI: 10.1002/jmv.27177

Abstract

We comment on the recently published paper by Pallotto et al. (2021;93(5):2631-2634.) who reported transient bradicardia in COVID-19 patients treated with remdesivir. We present the results of our own pilot study of remdesivir induced changes in electrocardiogram of severe COVID-19 patients where T axis deviation was the most pronounced finding after remdesivir infusion. T wave axis deviation is associated with propensity for sudden cardiac death and non-fatal cardiovascular events among elderly in the general population. This article is protected by copyright. All rights reserved.

Keywords: COVID-19; SARS-CoV-2; T wave axis deviation; remdesivir; sudden cardiac death.