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Perfusion. 2018 May 1:267659118778173. doi: 10.1177/0267659118778173. [Epub ahead of print]
Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency.
Hancock S1, Froehlich C2, Armijo-Garcia V3, Meyer AD3.
Author information
Abstract
INTRODUCTION:
Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry.
CASE REPORT:
A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support.
DISCUSSION:
The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO.
CONCLUSION:
ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.
KEYWORDS:
Jeune syndrome; extracorporeal membrane oxygenation; pediatrics; thoracic insufficiency; thoracic surgery
PMID: 29792118 DOI: 10.1177/0267659118778173
Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency.
Hancock S1, Froehlich C2, Armijo-Garcia V3, Meyer AD3.
Author information
Abstract
INTRODUCTION:
Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry.
CASE REPORT:
A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support.
DISCUSSION:
The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO.
CONCLUSION:
ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.
KEYWORDS:
Jeune syndrome; extracorporeal membrane oxygenation; pediatrics; thoracic insufficiency; thoracic surgery
PMID: 29792118 DOI: 10.1177/0267659118778173