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Adv Healthc Mater. 2013 Aug 27. doi: 10.1002/adhm.201300247. [Epub ahead of print]
Peptide Amphiphile Nanoparticles Enhance the Immune Response Against a CpG-Adjuvanted Influenza Antigen.
Zope H, Quer CB, Bomans PH, Sommerdijk NA, Kros A, Jiskoot W.
Source
Department of Soft Matter Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.
Abstract
Cationic peptide amphiphile nanoparticles are employed for co-delivery of immune modulator CpG and antigen. This results in better targeting to the antigen presenting cells and eliciting strong Th1 response, which is effective against the intracellular pathogens.
? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
KEYWORDS:
adjuvants, nanoparticles, peptide amphiphiles, self-assembly, vaccines
PMID:
23983195
[PubMed - as supplied by publisher]
Peptide Amphiphile Nanoparticles Enhance the Immune Response Against a CpG-Adjuvanted Influenza Antigen.
Zope H, Quer CB, Bomans PH, Sommerdijk NA, Kros A, Jiskoot W.
Source
Department of Soft Matter Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.
Abstract
Cationic peptide amphiphile nanoparticles are employed for co-delivery of immune modulator CpG and antigen. This results in better targeting to the antigen presenting cells and eliciting strong Th1 response, which is effective against the intracellular pathogens.
? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
KEYWORDS:
adjuvants, nanoparticles, peptide amphiphiles, self-assembly, vaccines
PMID:
23983195
[PubMed - as supplied by publisher]
