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Appl Biochem Biotechnol. 2013 Jan 10. [Epub ahead of print]
Antiviral and Antibacterial Polyurethanes of Various Modalities.
Park D, Larson AM, Klibanov AM, Wang Y.
Source
Department of Bioengineering, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA, daewon.park@ucdenver.edu.
Abstract
We have prepared and characterized a new polyurethane-based antimicrobial material, N,N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).
PMID:
23306899
[PubMed - as supplied by publisher]
Antiviral and Antibacterial Polyurethanes of Various Modalities.
Park D, Larson AM, Klibanov AM, Wang Y.
Source
Department of Bioengineering, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA, daewon.park@ucdenver.edu.
Abstract
We have prepared and characterized a new polyurethane-based antimicrobial material, N,N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).
PMID:
23306899
[PubMed - as supplied by publisher]
