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Bull Exp Biol Med. 2011 Apr;150(6):707-10.
Preventive Efficacy of Oxidized Dextran and Pathomorphological Processes in Mouse Lungs in Avian Influenza A/H5N1.
[Article in English, Russian]
Potapova OV, Shkurupiy VA, Sharkova TV, Troitskiy AV, Lusgina NG, Shestopalov AM.
Source
Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. potapova@soramn.ru.
Abstract
Oxidized dextran (60 kDa) exerts a pronounced preventive effect in laboratory mice infected with avian influenza subtype H5N1 A/Goose/Krasnoozerskoye/627/05 virus, which manifested in a significant increase in mouse lifetime (by 24.4%) and mortality rate (3.3-fold). This was probably related to significant alleviation of pathological changes in the lungs and severity of hemodynamic and inflammatory complications and early fibrosis.
PMID:
22235423
[PubMed - in process]
Preventive Efficacy of Oxidized Dextran and Pathomorphological Processes in Mouse Lungs in Avian Influenza A/H5N1.
[Article in English, Russian]
Potapova OV, Shkurupiy VA, Sharkova TV, Troitskiy AV, Lusgina NG, Shestopalov AM.
Source
Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. potapova@soramn.ru.
Abstract
Oxidized dextran (60 kDa) exerts a pronounced preventive effect in laboratory mice infected with avian influenza subtype H5N1 A/Goose/Krasnoozerskoye/627/05 virus, which manifested in a significant increase in mouse lifetime (by 24.4%) and mortality rate (3.3-fold). This was probably related to significant alleviation of pathological changes in the lungs and severity of hemodynamic and inflammatory complications and early fibrosis.
PMID:
22235423
[PubMed - in process]
