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Genome Announc. 2017 Aug 24;5(34). pii: e00802-17. doi: 10.1128/genomeA.00802-17.
Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck.
Xie L1, Xie Z1, Wu A2, Luo S2, Zhang M2, Huang L2, Xie Z2, Huang J2, Zhang Y2, Zeng T2, Deng X2.
Author information
Abstract
An H4N6 subtype avian influenza virus was isolated from a pockmark duck in southern China in November 2013 and named A/duck/Guangxi/149D24/2013 (H4N6). All eight gene segments of the strain were sequenced. Sequence analysis indicated that this H4N6 virus was a natural reassortant virus. This H4N6 virus has two basic amino acids in the cleavage site of hemagglutinin 1 (HA1) and HA2, and the amino acid motif of cleavage site was PEKASRGLF, which is the typical characteristic of the low-pathogenic avian influenza virus. This study will help understand the epidemiology and molecular characteristics of avian influenza virus in pockmark ducks.
Copyright ? 2017 Xie et al.
PMID: 28839020 DOI: 10.1128/genomeA.00802-17
Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck.
Xie L1, Xie Z1, Wu A2, Luo S2, Zhang M2, Huang L2, Xie Z2, Huang J2, Zhang Y2, Zeng T2, Deng X2.
Author information
Abstract
An H4N6 subtype avian influenza virus was isolated from a pockmark duck in southern China in November 2013 and named A/duck/Guangxi/149D24/2013 (H4N6). All eight gene segments of the strain were sequenced. Sequence analysis indicated that this H4N6 virus was a natural reassortant virus. This H4N6 virus has two basic amino acids in the cleavage site of hemagglutinin 1 (HA1) and HA2, and the amino acid motif of cleavage site was PEKASRGLF, which is the typical characteristic of the low-pathogenic avian influenza virus. This study will help understand the epidemiology and molecular characteristics of avian influenza virus in pockmark ducks.
Copyright ? 2017 Xie et al.
PMID: 28839020 DOI: 10.1128/genomeA.00802-17