Tweet
Influenza Other Respir Viruses. 2016 Jul 4. doi: 10.1111/irv.12402. [Epub ahead of print]
Influenza C infections in Western Australia and Victoria from 2008-14.
Jelley L1, Levy A2,3, Deng YM1, Spirason N1, Lang J2, Buettner I1, Druce J4, Blyth C5,6,7, Effler P3,5,8, Smith D2,8, Barr IG1,9.
Author information
Abstract
BACKGROUND:
Influenza C is usually considered a minor cause of respiratory illness in man with many infections being asymptomatic or clinically mild. Large outbreaks can occur periodically resulting in significant morbidity.
OBJECTIVES:
This study was aimed at analyzing the available influenza C clinical samples from two widely separated states of Australia, collected over a seven year period and to compare them with influenza C viruses detected in other parts of the world in recent years.
PATIENTS/METHODS:
Between 2008 and 2014, 86 respiratory samples that were influenza C positive were collected from subjects with influenza like illness living in the states of Victoria and Western Australia. A battery of other respiratory viruses were also tested for in these influenza C positive samples. Virus isolation was attempted on all of these clinical samples and gene sequencing was performed on all influenza C positive cultures.
RESULTS AND CONCLUSIONS:
Detections of influenza C in respiratory samples were sporadic in most years studied, but higher rates of infection occurred in 2012 and 2014. Many of the patients with influenza C had co-infections with other respiratory pathogens. Phylogenetic analysis of the full length haemagglutinin-esterase fusion (HE) gene found that most of the viruses grouped in the C/Sao Paulo/378/82 clade with the remainder grouping in the C/Kanagawa/1/76 clade. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Australia; children; influenza C; respiratory disease; viruses
PMID: 27373693 DOI: 10.1111/irv.12402
[PubMed - as supplied by publisher]
Influenza C infections in Western Australia and Victoria from 2008-14.
Jelley L1, Levy A2,3, Deng YM1, Spirason N1, Lang J2, Buettner I1, Druce J4, Blyth C5,6,7, Effler P3,5,8, Smith D2,8, Barr IG1,9.
Author information
Abstract
BACKGROUND:
Influenza C is usually considered a minor cause of respiratory illness in man with many infections being asymptomatic or clinically mild. Large outbreaks can occur periodically resulting in significant morbidity.
OBJECTIVES:
This study was aimed at analyzing the available influenza C clinical samples from two widely separated states of Australia, collected over a seven year period and to compare them with influenza C viruses detected in other parts of the world in recent years.
PATIENTS/METHODS:
Between 2008 and 2014, 86 respiratory samples that were influenza C positive were collected from subjects with influenza like illness living in the states of Victoria and Western Australia. A battery of other respiratory viruses were also tested for in these influenza C positive samples. Virus isolation was attempted on all of these clinical samples and gene sequencing was performed on all influenza C positive cultures.
RESULTS AND CONCLUSIONS:
Detections of influenza C in respiratory samples were sporadic in most years studied, but higher rates of infection occurred in 2012 and 2014. Many of the patients with influenza C had co-infections with other respiratory pathogens. Phylogenetic analysis of the full length haemagglutinin-esterase fusion (HE) gene found that most of the viruses grouped in the C/Sao Paulo/378/82 clade with the remainder grouping in the C/Kanagawa/1/76 clade. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Australia; children; influenza C; respiratory disease; viruses
PMID: 27373693 DOI: 10.1111/irv.12402
[PubMed - as supplied by publisher]