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Arch Virol. 2016 Jan 2. [Epub ahead of print]
Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes.
Chen D1, Wen X2, Sun Y3, Mao H4, Zhang Y4, Chen Y4, Wang X4, Sun B1, Wang X1, Zhang X1.
Author information
Abstract
Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions at the amino acid level. Phylogenetic analysis revealed co-circulation of the B/Victoria and B/Yamagata lineages in the Wenzhou area from 2011 to 2014. Multiple viral introductions from both Chinese and international sources played important roles in endemic co-circulation and transmission in coastal southeastern China.
KEYWORDS:
Influenza B virus; Molecular epidemiology; Phylogenetic; Victoria; Yamagata
PMID: 26724821 [PubMed - as supplied by publisher]
Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes.
Chen D1, Wen X2, Sun Y3, Mao H4, Zhang Y4, Chen Y4, Wang X4, Sun B1, Wang X1, Zhang X1.
Author information
Abstract
Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions at the amino acid level. Phylogenetic analysis revealed co-circulation of the B/Victoria and B/Yamagata lineages in the Wenzhou area from 2011 to 2014. Multiple viral introductions from both Chinese and international sources played important roles in endemic co-circulation and transmission in coastal southeastern China.
KEYWORDS:
Influenza B virus; Molecular epidemiology; Phylogenetic; Victoria; Yamagata
PMID: 26724821 [PubMed - as supplied by publisher]