Tweet
Epidemiol Infect. 2015 Sep 18:1-10. [Epub ahead of print]
Epidemiological features of influenza in Canadian adult intensive care unit patients.
Taylor G1, Abdesselam K2, Pelude L2, Fernandes R2, Mitchell R2, McGEER A3, Frenette C4, Suh KN5, Wong A6, Katz K7, Wilkinson K2, Mersereau T2, Gravel D2; Canadian Nosocomial Infection Surveillance Program (CNISP).
Author information
Abstract
To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed influenza in adult ICUs in a network of Canadian hospitals between 2006 and 2012. There were 626 influenza-positive patients admitted to ICUs over the six influenza seasons, representing 17?9% of hospitalized influenza patients, 3?1/10 000 hospital admissions. Variability occurred in admission rate and proportion of hospital influenza patients who were admitted to ICUs (proportion range by year: 11?7-29?4%; 21?3% in the 2009-2010 pandemic). In logistic regression models ICU patients were younger during the pandemic and post-pandemic period, and more likely to be obese than hospital non-ICU patients. Influenza B accounted for 14?2% of all ICU cases and had a similar ICU admission rate as influenza A. Influenza-related mortality was 17?8% in ICU patients compared to 2?0% in non-ICU patients.
KEYWORDS:
Critical care; epidemiology; hospital; influenza
PMID: 26384310 [PubMed - as supplied by publisher]
Epidemiological features of influenza in Canadian adult intensive care unit patients.
Taylor G1, Abdesselam K2, Pelude L2, Fernandes R2, Mitchell R2, McGEER A3, Frenette C4, Suh KN5, Wong A6, Katz K7, Wilkinson K2, Mersereau T2, Gravel D2; Canadian Nosocomial Infection Surveillance Program (CNISP).
Author information
Abstract
To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed influenza in adult ICUs in a network of Canadian hospitals between 2006 and 2012. There were 626 influenza-positive patients admitted to ICUs over the six influenza seasons, representing 17?9% of hospitalized influenza patients, 3?1/10 000 hospital admissions. Variability occurred in admission rate and proportion of hospital influenza patients who were admitted to ICUs (proportion range by year: 11?7-29?4%; 21?3% in the 2009-2010 pandemic). In logistic regression models ICU patients were younger during the pandemic and post-pandemic period, and more likely to be obese than hospital non-ICU patients. Influenza B accounted for 14?2% of all ICU cases and had a similar ICU admission rate as influenza A. Influenza-related mortality was 17?8% in ICU patients compared to 2?0% in non-ICU patients.
KEYWORDS:
Critical care; epidemiology; hospital; influenza
PMID: 26384310 [PubMed - as supplied by publisher]