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J Med Virol. 2013 Oct 17. doi: 10.1002/jmv.23786. [Epub ahead of print]
Viruses associated with influenza-like-illnesses in Papua New Guinea, 2010.
Kono J, Jonduo MH, Omena M, Siba PM, Horwood PF.
Source
Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
Abstract
Influenza-like-illness can be caused by a wide range of respiratory viruses. The etiology of influenza-like-illness in developing countries such as Papua New Guinea is poorly understood. The etiological agents associated with influenza-like-illness were investigated retrospectively for 300 nasopharyngeal swabs received by the Papua New Guinea National Influenza Centre in 2010. Real-time PCR/RT-PCR methods were used for the detection of 13 respiratory viruses. Patients with influenza-like-illness were identified according to the World Health Organization case definition: sudden onset of fever (>38?C), with cough and/or sore throat, in the absence of other diagnoses. At least one viral respiratory pathogen was detected in 66.3% of the samples tested. Rhinoviruses (17.0%), influenza A (16.7%), and influenza B (12.7%) were the pathogens detected most frequently. Children <5 years of age presented with a significantly higher rate of at least one viral pathogen and a significantly higher rate of co-infections with multiple viruses, when compared to all other patients >5 years of age. Influenza B, adenovirus, and respiratory syncytial virus were all detected at significantly higher rates in children <5 years of age. This study confirmed that multiple respiratory viruses are circulating and contributing to the presentation of influenza-like-illness in Papua New Guinea. J. Med. Virol. ? 2013 Wiley Periodicals, Inc.
? 2013 Wiley Periodicals, Inc.
KEYWORDS:
Papua New Guinea, influenza, respiratory, virus
PMID:
24136362
[PubMed - as supplied by publisher]
Viruses associated with influenza-like-illnesses in Papua New Guinea, 2010.
Kono J, Jonduo MH, Omena M, Siba PM, Horwood PF.
Source
Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
Abstract
Influenza-like-illness can be caused by a wide range of respiratory viruses. The etiology of influenza-like-illness in developing countries such as Papua New Guinea is poorly understood. The etiological agents associated with influenza-like-illness were investigated retrospectively for 300 nasopharyngeal swabs received by the Papua New Guinea National Influenza Centre in 2010. Real-time PCR/RT-PCR methods were used for the detection of 13 respiratory viruses. Patients with influenza-like-illness were identified according to the World Health Organization case definition: sudden onset of fever (>38?C), with cough and/or sore throat, in the absence of other diagnoses. At least one viral respiratory pathogen was detected in 66.3% of the samples tested. Rhinoviruses (17.0%), influenza A (16.7%), and influenza B (12.7%) were the pathogens detected most frequently. Children <5 years of age presented with a significantly higher rate of at least one viral pathogen and a significantly higher rate of co-infections with multiple viruses, when compared to all other patients >5 years of age. Influenza B, adenovirus, and respiratory syncytial virus were all detected at significantly higher rates in children <5 years of age. This study confirmed that multiple respiratory viruses are circulating and contributing to the presentation of influenza-like-illness in Papua New Guinea. J. Med. Virol. ? 2013 Wiley Periodicals, Inc.
? 2013 Wiley Periodicals, Inc.
KEYWORDS:
Papua New Guinea, influenza, respiratory, virus
PMID:
24136362
[PubMed - as supplied by publisher]
