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Influenza Other Respi Viruses. 2013 May 27. doi: 10.1111/irv.12128. [Epub ahead of print]
Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment.
Dlugolenski D, Jones L, Tompkins SM, Crameri G, Wang LF, Tripp RA.
Source
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Abstract
Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow-shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that Pteropus alecto kidney cells (PaKi) are susceptible to infection and sustain replication of A/WSN/33 (H1N1) and A/Vietnam/1203/04 (H5N1). Importantly, we show that co-infection of PaKi cells results in novel reassortants.
? 2013 John Wiley & Sons Ltd.
PMID:
23710888
[PubMed - as supplied by publisher]
Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment.
Dlugolenski D, Jones L, Tompkins SM, Crameri G, Wang LF, Tripp RA.
Source
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Abstract
Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow-shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that Pteropus alecto kidney cells (PaKi) are susceptible to infection and sustain replication of A/WSN/33 (H1N1) and A/Vietnam/1203/04 (H5N1). Importantly, we show that co-infection of PaKi cells results in novel reassortants.
? 2013 John Wiley & Sons Ltd.
PMID:
23710888
[PubMed - as supplied by publisher]
