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Am J Trop Med Hyg. 2013 Feb 4. [Epub ahead of print]
Acute Febrile Illness Surveillance in a Tertiary Hospital Emergency Department: Comparison of Influenza and Dengue Virus Infections.
Lorenzi OD, Gregory CJ, Santiago LM, Acosta H, Galarza IE; Saint Luke's Acute Febrile Illness Investigation Team, Hunsperger E, Mu?oz J, Bui DM, Oberste MS, Pe?aranda S, Garcia-Gubern C, Tomashek KM.
Source
Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico; Ponce School of Medicine/Saint Luke's Episcopal Hospital, Ponce, Puerto Rico; Saint Luke's Acute Febrile Illness Investigation Team, Saint Luke's Episcopal Hospital Ponce, Puerto Rico; Zoonotic and Select Agent Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia; Polio and Picornavirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Abstract
In 2009, an increased proportion of suspected dengue cases reported to the surveillance system in Puerto Rico were laboratory negative. As a result, enhanced acute febrile illness (AFI) surveillance was initiated in a tertiary care hospital. Patients with fever of unknown origin for 2-7 days duration were tested for Leptospira, enteroviruses, influenza, and dengue virus. Among the 284 enrolled patients, 31 dengue, 136 influenza, and 3 enterovirus cases were confirmed. Nearly half (48%) of the confirmed dengue cases met clinical criteria for influenza. Dengue patients were more likely than influenza patients to have hemorrhage (81% versus 26%), rash (39% versus 9%), and a positive tourniquet test (52% versus 18%). Mean platelet and white blood cell count were lower among dengue patients. Clinical diagnosis can be particularly difficult when outbreaks of other AFI occur during dengue season. A complete blood count and tourniquet test may be useful to differentiate dengue from other AFIs.
PMID:
23382160
[PubMed - as supplied by publisher]
Free full text
Acute Febrile Illness Surveillance in a Tertiary Hospital Emergency Department: Comparison of Influenza and Dengue Virus Infections.
Lorenzi OD, Gregory CJ, Santiago LM, Acosta H, Galarza IE; Saint Luke's Acute Febrile Illness Investigation Team, Hunsperger E, Mu?oz J, Bui DM, Oberste MS, Pe?aranda S, Garcia-Gubern C, Tomashek KM.
Source
Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico; Ponce School of Medicine/Saint Luke's Episcopal Hospital, Ponce, Puerto Rico; Saint Luke's Acute Febrile Illness Investigation Team, Saint Luke's Episcopal Hospital Ponce, Puerto Rico; Zoonotic and Select Agent Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia; Polio and Picornavirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Abstract
In 2009, an increased proportion of suspected dengue cases reported to the surveillance system in Puerto Rico were laboratory negative. As a result, enhanced acute febrile illness (AFI) surveillance was initiated in a tertiary care hospital. Patients with fever of unknown origin for 2-7 days duration were tested for Leptospira, enteroviruses, influenza, and dengue virus. Among the 284 enrolled patients, 31 dengue, 136 influenza, and 3 enterovirus cases were confirmed. Nearly half (48%) of the confirmed dengue cases met clinical criteria for influenza. Dengue patients were more likely than influenza patients to have hemorrhage (81% versus 26%), rash (39% versus 9%), and a positive tourniquet test (52% versus 18%). Mean platelet and white blood cell count were lower among dengue patients. Clinical diagnosis can be particularly difficult when outbreaks of other AFI occur during dengue season. A complete blood count and tourniquet test may be useful to differentiate dengue from other AFIs.
PMID:
23382160
[PubMed - as supplied by publisher]
Free full text
