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Am J Trop Med Hyg. 2012 Feb;86(2):246-53.
Infectious Etiologies of Acute Febrile Illness among Patients Seeking Health Care in South-Central Cambodia.
Kasper MR, Blair PJ, Touch S, Sokhal B, Yasuda CY, Williams M, Richards AL, Burgess TH, Wierzba TF, Putnam SD.
Source
United States Naval Medical Research Unit 2, Jakarta, Indonesia; Control of Communicable Disease Department, Ministry of Health, Phnom Penh, Cambodia; National Institute of Public Health, Ministry of Health, Phnom Penh, Cambodia; United States Naval Medical Research Unit No. 2, Phnom Penh, Cambodia; Naval Medical Research Center, Silver Spring, Maryland.
Abstract
Abstract. The agents of human febrile illness can vary by region and country suggesting that diagnosis, treatment, and control programs need to be based on a methodical evaluation of area-specific etiologies. From December 2006 to December 2009, 9,997 individuals presenting with acute febrile illness at nine health care clinics in south-central Cambodia were enrolled in a study to elucidate the etiologies. Upon enrollment, respiratory specimens, whole blood, and serum were collected. Testing was performed for viral, bacterial, and parasitic pathogens. Etiologies were identified in 38.0% of patients. Influenza was the most frequent pathogen, followed by dengue, malaria, and bacterial pathogens isolated from blood culture. In addition, 3.5% of enrolled patients were infected with more than one pathogen. Our data provide the first systematic assessment of the etiologies of acute febrile illness in south-central Cambodia. Data from syndromic-based surveillance studies can help guide public health responses in developing nations.
PMID:
22302857
[PubMed - in process]
Infectious Etiologies of Acute Febrile Illness among Patients Seeking Health Care in South-Central Cambodia.
Kasper MR, Blair PJ, Touch S, Sokhal B, Yasuda CY, Williams M, Richards AL, Burgess TH, Wierzba TF, Putnam SD.
Source
United States Naval Medical Research Unit 2, Jakarta, Indonesia; Control of Communicable Disease Department, Ministry of Health, Phnom Penh, Cambodia; National Institute of Public Health, Ministry of Health, Phnom Penh, Cambodia; United States Naval Medical Research Unit No. 2, Phnom Penh, Cambodia; Naval Medical Research Center, Silver Spring, Maryland.
Abstract
Abstract. The agents of human febrile illness can vary by region and country suggesting that diagnosis, treatment, and control programs need to be based on a methodical evaluation of area-specific etiologies. From December 2006 to December 2009, 9,997 individuals presenting with acute febrile illness at nine health care clinics in south-central Cambodia were enrolled in a study to elucidate the etiologies. Upon enrollment, respiratory specimens, whole blood, and serum were collected. Testing was performed for viral, bacterial, and parasitic pathogens. Etiologies were identified in 38.0% of patients. Influenza was the most frequent pathogen, followed by dengue, malaria, and bacterial pathogens isolated from blood culture. In addition, 3.5% of enrolled patients were infected with more than one pathogen. Our data provide the first systematic assessment of the etiologies of acute febrile illness in south-central Cambodia. Data from syndromic-based surveillance studies can help guide public health responses in developing nations.
PMID:
22302857
[PubMed - in process]
