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Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina: are we facing the expansion of potential epicenters of influenza emergence?

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  • Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina: are we facing the expansion of potential epicenters of influenza emergence?

    SHORT COMMUNICATION
    Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina: are we facing the expansion of potential epicenters of influenza emergence?

    1. Ariel Pereda1,
    2. Agustina Rimondi1,
    3. Javier Cappuccio2,
    4. Ramon Sanguinetti3,
    5. Matthew Angel4,
    6. Jianqiang Ye4,
    7. Troy Sutton4,
    8. Marina Dib?rbora1,
    9. Valeria Olivera1,
    10. Maria I. Craig1,
    11. Maria Quiroga2,
    12. Mariana Machuca2,
    13. Andrea Ferrero4,
    14. Carlos Perfumo2,
    15. Daniel R. Perez4

    Article first published online: 7 APR 2011

    DOI: 10.1111/j.1750-2659.2011.00246.x

    ? 2011 Blackwell Publishing Ltd



    Please cite this paper as: Pereda et al. (2011) Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina: are we facing the expansion of potential epicenters of influenza emergence? Influenza and Other Respiratory Viruses Doi: 10.1111/j.1750-2659.2011.00246.x.

    In this report, we describe the occurrence of two novel swine influenza viruses (SIVs) in pigs in Argentina. These viruses are the result of two independent reassortment events between the H1N1 pandemic influenza virus (H1N1pdm) and human-like SIVs, showing the constant evolution of influenza viruses at the human?swine interface and the potential health risk of H1N1pdm as it appears to be maintained in the swine population. It must be noted that because of the lack of information regarding the circulation of SIVs in South America, we cannot discard the possibility that ancestors of the H1N1pdm or other SIVs have been present in this part of the world. More importantly, these findings suggest an ever-expanding geographic range of potential epicenters of influenza emergence with public health risks.

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